Sunday 30 June 2019

Herbal Turmeric, the Potent Anti Facial Skin-Aging Functional Remedy

By Kyle J. Norton

Facial aging is a biological process caused by the structural rearrangements on the face, uneven fat distribution in the face, leading to wrinkles and pockets plumped up the forehead, temples, cheeks, and areas around the eyes and mouth.

Aging caused by the gravity, fats that support the firming of the face loses volume, clumps up, and shifts downward accompanied by the natural degeneration of the skin can also contribute to facial aging.

Also, the facial muscles continually tug on, leading to the formation of facial wrinkle.

Besides aging, wrinkles may be caused by long-term exposure to the sun by smoking.

However, in North America, the wrong perception of sun exposure is one of the extrinsic factors that add burden to natural facial aging.

Dr. Frederic Flament, wrote, "During a lifetime, skin will change in appearance and structure not only because of chronological and intrinsic processes but also due to several external factors such as gravity, sun and ultraviolet exposure, and high levels of pollution; or lifestyle factors that have important and obvious effects on skin aging, such as diet, tobacco, illness, or stress".

And, "Clinical signs of aging are essentially influenced by extrinsic factors, especially sun exposure. Indeed UV exposure seems to be responsible for 80% of visible facial aging signs".



Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia.

The herb has been used in traditional medicine as anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and for the treatment of flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.

On finding a better compound for the treatment of facial photoaging, researchers examined curcumin, the main ingredient from turmeric and turmeric extract in the promotion of healthy skin and inhibition of wrinkle formation caused by exposure to UV radiation.

According to the tested assays, curcumin exerted the strong effect on the deposition of basement membrane component at dermal-epidermal junction in the skin equivalent model.

Topical application of a cream containing turmeric extract in UV radiation-induced facial photoaging significantly improved facial skin elasticity and decreased the number of gelatinase-positive stratum corneum clusters in human facial skins.

Based on the results, researchers wrote in the final report, "These results indicated that turmeric is an effective ingredient to improve skin condition and to prevent skin from photoaging by suppressing activation of gelatinase chronically caused by UV".

In chronic ultraviolet B (UVB)-irradiated skin damage in melanin-possessing hairless mice, turmeric extract improved the skin thickness and elasticity caused by long-term, low-dose ultraviolet B irradiation at 300 or 1000 mg/kg, applied twice daily.

Furthermore, at 1000 mg/kg, applied twice daily, the extract also prevented the formation of wrinkles and melanin and diameter and length of skin blood vessels and the expression of the enzyme (matrix metalloproteinase-2 (MMP-2)) in the inhibition of elastin, a highly elastic protein in the production of connective tissue.

Dr. Sumiyoshi M. the lead scientist after taking other factors into account wrote, "(Turmeric extract) Prevention of UVB-induced skin aging by turmeric may be due to the inhibition of increases in MMP-2 expression caused by chronic irradiation"

Taken altogether, turmeric in form of extract may be considered supplements for the prevention and treatment of facial photoaging, pending to the confirmation of the larger sample size and multicenter human study.

Intake of turmeric in the form of supplement should be taken with extreme care to prevent overdose acute liver toxicity.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Inhibitory effect of the extract of rhizome of Curcuma longa L in gelatinase activity and its effect on human skin by Muta K1, Inomata S2, Fukuhara T2, Nomura J2, Nishiyama T3, Tagawa YI4, Amano S2. (PubMed)
(2) Effects of a turmeric extract (Curcuma longa) on chronic ultraviolet B irradiation-induced skin damage in melanin-possessing hairless mice by Sumiyoshi M1, Kimura Y. (PubMed)
(3) Effect of the sun on visible clinical signs of aging in Caucasian skin by Frederic Flament,1 Roland Bazin,2 Sabine Laquieze,3 Virginie Rubert,1 Elisa Simonpietri,4and Bertrand Piot. (PMC)

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