Endometriosis is a medical condition characterized by the growth of endometrial cells somewhere else instead of the inside of the uterus.
*55% of women who have developed the new onset of severe menstrual cramps.
* 25% of women with sub-fertility (less fertile than a normal couple)
Commonly they are found on the top surface, of the inside wall of uterus, ligaments, and ovary with a few in numbers.
* Mild stage:
Deeper implants, greater numbers are presented. Commonly found in the same area as a minimal stage.
* Moderate stage:
Many implants, endometrial cysts present, affecting ovary function, causing scar tissues and adhesion are also present.
* Severe stage:
Intensive peritoneal implants, large endometromas present and dense adhesion.
Each woman experiences differently to endometriosis. Some women may have extensive endometrial tissues in their body but feel little or no pain at all, compared to other women in the early stage of endometriosis with excessive pain.
On finding a potential compound for the treatment of endometriosis, researchers evaluated the efficacy of an association of N-acetyl cysteine, alpha-lipoic acid, and bromelain (NAC/LA/Br) in vivo murine model and in vitro human endometriotic endothelial cells (EECs) and on endothelial cells isolated from the normal uterus (UtMECs.
More precisely, compared to the baseline of 92.7% of the patients had pain intensity > 4 on the visual analog scale (VAS); treatment of NAC/LA/Br at 3 months decreased the percentage of patients to 87.2% (p = 0.074) and at 6 months to 82.7%, respectively.
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Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
(1) Effectiveness of an antioxidant preparation with N-acetyl cysteine, alpha lipoic acid and bromelain in the treatment of endometriosis-associated pelvic pain: LEAP study by Lete I1, Mendoza N2, de la Viuda E3, Carmona F. (PubMed)
(2) The combination of N-acetyl cysteine, alpha-lipoic acid, and bromelain shows high anti-inflammatory properties in novel in vivo and in vitro models of endometriosis by Agostinis C1, Zorzet S2, De Leo R1, Zauli G1, De Seta F3, Bulla R. (PubMed)
(3) Endometriosis part I - Definition, Stages, Symptoms, Causes, and Effects Of Endometriosis by Kyle J. Norton