Tuesday 25 June 2019

Healthy Food Turmeric Protects the Skin Damage Against Aging

By Kyle J. Norton

Skin aging is a natural process that can not be stopped. However, there are some people have a younger looking skin compared to their biological age.

The evidence of skin aging can be visible by increasing wrinkles and sagging skin.

Skin is the largest organ in the human body. The skin not only shields us against the invasion of foreigner pathogens but also serves as the third detoxed organ besides the liver and kidney.

Additionally, the skin also protects the skeletons and internal organs against the mechanical impacts and pressure, variations in temperature, micro-organisms, radiation, and chemicals.

However, when skin ages, it also reduces the function of the aforementioned protection as seen in the elderly.

Besides biological causes of skin aging, long-term exposure to sunlight, particularly UVB is one of the major culprit associated with damages of elastin, leading to wrinkles, sagging skin that loses stability to rebound from the stretch.

According to the free radical theory of aging, free radical bombardment overtime can cause oxidative damage to the enzymes, other protein, unsaturated fatty acid, phospholipids, DNA and RNA, leading widespread cell damage including the skin cells after attacking the lipid bilayers of the cell walls.

In other words, according to the theory, free radical cause internal and external cell damage, that lead to aging cells.

Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia.

The herb has been used in traditional medicine as anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and to treat flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.

On finding a natural and effective compound for the protection against skin aging, researchers examined the effects of curcumin in acute and chronic injury: burns and photo-damaged skin.

In photo-damaged skin, injection of curcumin inhibited the phosphorylase kinase (PhK) which plays an important role in promoting photocarcinogenesis and skin damage through activation of NF-kB-dependent signaling pathways.

In other words, curcumin inhibited phosphorylase kinase (PhK) in the induction of the apoptosis of photo-damaged cells, thus promoting the survival of precancerous cells and allowing for subsequent tumor transformation.

In the treatment of skin injury, application of a curcumin gel showed rapid healing of burns, with little or no residual scarring.

Furthermore, the curcumin gel was also beneficial in the repair of photo-damaged skin, including pigmentary changes, solar elastosis, thinning of the skin with telangiectasia (actinic poikiloderma), and premalignant lesions such as actinic keratoses, dysplastic nevi, and advanced solar lentigines, but the repair process takes many months.

In order to know more information about turmeric anti-photoaging activity, researchers looked into anti-skin aging due to intrinsic (chronologic) and extrinsic aging (photo-aging) of plants from 35 families.

Curcumin found in turmeric not only showed potency in the inhibition of tyrosinase, hyaluronidase, elastase, and collagenase associated with skin aging induced by UV radiation but also scavenges free radicals from skin cells, prevents trans-epidermal water loss and contributes to protecting skin from wrinkles.

In summary, curcumin protects the skin against aging intrinsically (chronologic) and extrinsically. 

Taken altogether, turmeric processed a high amount of bioactive compound curcumin may be considered supplements for the prevention and treatment of skin aging, pending to the confirmation of the larger sample size and multicenter human study.

Intake of turmeric in the form of supplement should be taken with extreme care to prevent overdose acute liver toxicity.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Signaling pathways targeted by curcumin in acute and chronic injury: burns and photo-damaged skin by Heng MC. (PubMed)
(2) Potential role of natural compounds against skin aging by Tundis R, Loizzo MR, Bonesi M, Menichini F. (PubMed)

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