Neuroprotection is an action induced the preservation of neuronal structure and/or function, including the use of medicines and herbs.
And, "Dose-response analysis indicated a 4 g/day increment of saturated fat intake was related to 15% higher risk of AD (RR: 1.15; 95% CI: 1.01, 1.31)".
In the urgency to discover a natural and potential compound for the treatment of neurodegenerative disease, scientists examined the alliin neuroprotective activity.
In vitro, alliin exerted a significant effect to protect neuronal cells integrity and viability against beta-amyloid (A) toxicity and apoptosis.
Furthermore, also in vitro, alliin inhibited oxidative stress caused by overexpression of reactive oxygen species (ROS) in cells in facilitating several neurodegenerative diseases including Alzheimer's disease (AD).
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Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
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Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
(1) Neuroprotective Effects of Garlic A Review by BC Mathew and RS Biju. (PubMed)
(2) Alliin, a garlic (Allium sativum) compound, prevents LPS-induced inflammation in 3T3-L1 adipocytes by Quintero-Fabián S1, Ortuño-Sahagún D2, Vázquez-Carrera M3, López-Roa RI. (PubMed)
(3) Dietary Fat Intake and Risk of Alzheimer's Disease and Dementia: A Meta-Analysis of Cohort Studies by bRuan Y1, Tang J1, Guo X1, Li K2, Li D. (PubMed)