Sunday, 30 June 2019

Navy Bean, Ameliorates Glycemic Stress of Diabetes in VIvo

By Kyle J. Norton

Diabetes is a chronic condition caused by insufficient insulin entering the bloodstream to regulate the glucose.

In other words, diabetes occurs when cells in pancreas dying off or receptor sites clogged up by fat and cholesterol. In some cases, diabetes is also caused by allergic reactions of cells in the immune system.

Most common forms of Diabetes are
* Type 1 diabetes, also known as juvenile diabetes or insulin-dependent diabetes, the most common form diabetes found in children is a condition in which the pancreas does not produce any insulin. Most common form of type 1 diabetes is caused by genetic mutation and some viruses.

As of today, there is no cure for type 1 diabetes. Treatment is focusing on managing blood sugar levels with insulin injection, diet, and lifestyle change.

* Type 2 diabetes, the most common form of acquired diabetes in adulthood is a chronic condition that affects the body metabolized glucose. In other words, most cases of type 2 diabetes are results of insulin receptors clogged-up by fat and cholesterol, leading to resist the effects of the hormone insulin that regulates the movement of sugar into your cells.

* Gestational diabetes is a form of diabetes that can occur during pregnancy, affecting between 3% and 20% of pregnant women.

Women with gestational diabetes are at an increased risk of type 2 diabetes in later life.

Most common symptoms of diabetes are excessive thirst and hunger, frequent urination, unintended weight loss or gain, frequent fatigue, irritability and gastrointestinal symptoms such as nausea.

In severe case, patients may also experience symptoms of blurred vision and slow wound healing or ulcer.

The small, white navy bean, also called pea bean or haricot, popular in both dry and green forms, is very popular in Britain and the US, native to Peru. The bean is now grown and consumed across the world, due to their numerous health benefits.

With an aim to find a potential compound for the management of diabetes, researchers investigated that the effect on glucose response of navy bean flour prepared as unleavened bread.

According to the tested assays
* Removal of phytic acid and addition of Ca to navy bean flour increased the starch digestion in vitro and raised the glycemic response

* However, readdition of phytic acid to dephytinized flour produced the opposite effect, in vivo.

In other words,  phytic acid found in navy bean increased the slow digestion of navy bean that benefits the management of diabetes and hyperlipidemia.

Also, according to the carbohydrate malabsorption assessed by breath H2 measurement, phytic acid has a strong influence related negatively to glycemic response.

Based on the findings, researchers said, " role of both added and endogenous phytic acid in slowing the in vitro rate of starch digestibility and in vivo glycemic response to legumes and the ability of Ca modify this effect".

Additionally, Dr. Hutchins AM, the lead scientists in the examined the effect of beans consumption such as pinto, black, navy or kidney in the prevention and treatment of chronic diseases suggested that
* Dietary beans reduced the glycemic stress such as hyperglycemia and hyperinsulinemia in patients with diabetes, CVD and cancer.
* Patients who eat more of these beans improved the glycaemic response and reduced the risk of developing diabetes, CVD and cancer.

Taken altogether, navy bean used alone or combined with conventional medicine may be considered a remedy for the management of diabetes,  pending to the confirmation of the larger sample size and multicenter human study.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

(1) Phytic acid and calcium affect the in vitro rate of navy bean starch digestion and blood glucose response in humans by Thompson LU, Button CL, Jenkins DJ. (PubMed)
(1) Phaseolus beans: impact on glycaemic response and chronic disease risk in human subjects by Hutchins AM1, Winham DM, Thompson SV. (PubMed)
(3) Diabetes – The Symptoms by Kyle J. Norton

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