Thursday, 6 June 2019

Healthy Legume Navy Bean Promotes the Healthy Gut Bacterial Metabolism

By Kyle J. Norton

Gut microbiota is a community of microbes living in the gastrointestinal tract, including at least 1000 different species of known bacteria with more than 3 million genes.

Normally, the ratio of good and bad microbes in the gut are balanced. However, people who have a psychological condition such as anxiety, and depression, and are under constant stress and long-term use of antibiotics, particularly your diet may have a negative impact on the ratio.

In other words, the risk factors that alter the ratio of the microbes in the gut may lead to inflammation, oxidative stress, and blood sugar imbalances.

The impact of gut microbes can also have a strong influence on what the human host is able to extract from its diet, both nutritionally and energetically.

Epidemiological studies suggested overweight and obese people show a dysbiosis characterized by a lower diversity. In other words, imbalanced gut microbiota dysbiosis promotes diet-induced obesity and metabolic complications.

Some researchers suggested that we can optimize our health by manipulating the gut microbiota through diet by increasing the intake of prebiotic and probiotic foods.

However, the benefits may totally depend on their effect on the resident community which is different individually.

Dr. Hall A, the lead scientist in the study of microbial metabolism in the mammalian gut, wrote, "Microbial dysbiosis, however, has been implicated in a number of human disorders, including obesity and inflammation. This dichotomy highlights the need to understand the factors that determine the composition and metabolic output of our resident and transient microbes".

And, " Throughout the human lifespan, we know that diet plays a major role in shaping gut microbial communities, as well as directing the types and amounts of metabolites produced. Understanding the factors that affect microbial metabolic output within the host may help identify the roles of microbes in health, as well as new targets for treatment in disease".

The small, white navy bean, also called pea bean or haricot, popular in both dry and green forms, is very popular in Britain and the US, native to Peru. It is now grown and consumed across the world, due to their numerous health benefits.

On finding a natural compound for the improvement of gut microbiota, researchers examined the effects of heat-stabilized rice bran (SRB) and cooked navy bean powder (NBP) phytochemicals on colonic microbiota and intestinal health.

The experiment included a total of 29 overweight/obese volunteers with a prior history of colorectal cancer consumed a study-provided meal and snack daily including eating SRB (30 g/day) or cooked navy bean powder (35 g/day) on gut microbiota and metabolites for 28 days.

Based on the tested assays,
* SRB or NBP showed increased gut bacterial diversity and altered gut microbial composition at 28 days compared to baseline in favor of the "good" bacterias.

* Supplementation with SRB or NBP increased total dietary fiber intake similarly, compared to the decrease of rice bran intake.

* More precisely, the Firmicutes: Bacteroidetes ratio is increased and SCFA (propionate and acetate) associated with chronic inflammatory disease in the stool is decreased after 14 days but not at 28 days.

The results strongly suggested that the efficacy of cooked navy bean in the re-balanced the gut microbiomes in favor of the good bacterias may be attributed to fiber contents in the interaction with
phytochemicals in the bean.

Dr. Sheflin AM, the lead scientist said, " modulation of gut microbiota and fermentation byproducts by SRB and suggest that foods with similar ability to increase dietary fiber intake may not have equal effects on gut microbiota and microbial metabolism".

Taken altogether, the cooked-navy bean may be considered a remedy for the improvement of gut microbiota, pending to the confirmation of the larger sample size and multicenter human study.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

(1) Dietary supplementation with rice bran or navy bean alters gut bacterial metabolism in colorectal cancer survivors by Sheflin AM1, Borresen EC2, Kirkwood JS3, Boot CM4, Whitney AK1, Lu S1, Brown RJ5, Broeckling CD3, Ryan EP2, Weir TL. (PubMed)
(2) Microbial Metabolism in the Mammalian Gut: Molecular Mechanisms and Clinical Implications.
Hall A, and Versalovic J. (PubMed)

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