Fennel may have a potential and positive effect in induction of cytoprotection and antitumor activity against cancer expression, some scientists suggested.
The results of fennel efficacy were reported by several respectable institutes including National Cancer Institute and National Institute of Health.
Fennel (Foeniculum vulgare) is a plant species of genus, belongings to Apiaceae (Umbelliferae), native to the Mediterranean, used in traditional and herbal medicine as warming, carminative, antispasmodic, antidepressant agent and to stimulate the appetite, ease indigestion, soothe coughing, reduce intestinal spasms, to regulate the menstrual cycle and relieve PMS,...
4. Thiamine (Vitamin B1)
5. Riboflavin (Vitamin B2)
6. Niacin (Vitamin B3)
7. Pantothenic acid (B5)
8. Vitamin B6
9. Folate (Vitamin B9)
10. Vitamin C
In the study to evaluate the efficacy of fennel seed methanolic extract (FSME) for its antioxidant, cytotoxic, and antitumor activities and for its capacity to serve as a nontoxic radioprotector in Swiss albino mice through injection of FSME, 100 mg/kg intraperitoneally into mice bearing EAC before exposed to three 2-Gy doses of gamma irradiation, researchers found at after 30 days, the application extered a strong effect at the C50 (mean standard deviation 50% inhibitory concentrations) at dose of 50 μg/mL for the MCF7 breast cancer cell line and 48 μg/mL for the Hepg-2 liver cancer cell line.
* Improved natural antioxidants and the oxidative stability of fatty foods during storage.
Further illustration of the effect of herbal medicine in treatment of cancers and examine the cytoprotective effects, researchers at the National Institute of Health conducted a comparison of five herbal supplements, designated FB, FM, PP, HF and FBL101, which contain different combinations of various natural herbs such as licorice, black cohosh, Dong Quai, false unicorn and vitex berry root against mice bearing CWR22R and PC3 prostate cancer xenografts.
According to the results of experiment,
* In CWR22R tumors, application of all supplements exerted a similar effect in suppression the of the cancer cells.
According to the results of report, application of Ethanol extract of Foeniculum vulgare exhibited significant inhibition of cancer cells proliferation and induction of cancer cell apoptosis and reduction of growth of Klebsiella pneumonia, Serratia marcescens and Methicillin-resistant S. aureus. Pseudomonas aeruginosa
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Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
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Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
(1) Antioxidant and anticarcinogenic effects of methanolic extract and volatile oil of fennel seeds (Foeniculum vulgare) by Mohamad RH1, El-Bastawesy AM, Abdel-Monem MG, Noor AM, Al-Mehdar HA, Sharawy SM, El-Merzabani MM.(PubMed)
(2) Antitumor activity of herbal supplements in human prostate cancer xenografts implanted in immunodeficient mice by Ng SS1, Figg WD.(PubMed)
(3) Study of anticancer and antibacterial activities of Foeniculum vulgare, Justicia adhatoda and Urtica dioica as natural curatives by Batool R1, Salahuddin H1, Mahmood T1, Ismail M2.(PubMed)