Saturday 23 May 2020

Herbal Angelica, a Promising Herbal Remedy for the Treatment of Chronic Kidney Diseases

By Kyle J. Norton

Kidneys are 2 bean-shaped organs found in the left and right side in the retroperitoneal space in the body.

The function of kidneys is to filter blood and control fluids. They are the second detoxed organs besides the liver and skin.

Other functions of kidneys are regulating and filtering minerals from the blood and producing hormones associated with the production of red blood cells, promote bone health, and regulate blood pressure.

Due to millions of tiny filters called nephrons in each kidney, people may not experience any kidney dysfunction symptoms at an early stage.

Kidney diseases are a class of medical conditions associated with reduced function of the kidney, in some cases, it is a complete loss of kidney function such as kidney failure.

Believe it or not, in the US, the leading causes of kidney failure and the end stage of chronic kidney diseases are diabetes and high blood pressure.

According to the statistics, in the US, over 660,000 Americans have kidney failure, affecting 14% of the general population.

Acute kidney diseases in most cases are associated with overdose of toxin or chronic. Acute kidney diseases can be cured if the underlying cause is found.

Chronic kidney disease (CKD) is a slow and progressive disease that can lead to kidney failure over time.

At the advanced of CKD can cause the dangerous levels of fluid, electrolytes and wastes build up in the body.

According to statistics, approximately 14 percent of the US general population suffer from CKD. Believe it or not, more than 661,000 Americans have kidney failure. Of these, 468,000 individuals are on dialysis, and roughly 193,000 live with a functioning kidney transplant.

On finding a natural ingredient for the prevention and treatment of kidney diseases, scientists compared the therapeutic effect of Astragalus and Angelica Mixture (AAM) on treating CKD patients.

Angelica or Dang Qui is a herb of Genus Angelica from the family Apiaceae, indigenous to China.

The herb has been used as a Queen herb in traditional Chinese medicine antispasmodic and vasodilatory agent, and to balance the hormones in women for a normal menstrual cycle and menstruation and strengthen heart, spleen, kidneys, and liver for both men and women, etc. In other words, it is used to treat gynecological ailments, fatigue, mild anemia, and high blood pressure. It has analgesic, anti-inflammatory, etc.

The multicentre, open-label, and self-control clinical design with thirty-two patients who maintain their previous basic CKD treatment, were given additionally took AAM (Astragalus and Angelica each 30 g), once a day, three months consisted of one therapeutic course.

According to the results of the experiment,
* AAM could improve 78.12% (25/32) patients' renal function.

* At the end of the 3-month treatment, Compared with before treatment, AAM decreased the Serum creatinine (SCr), increased the glomerular filtration rate (eG- FR), and plasma albumin (ALB) (2.76% +/- 1.97%) compared with before treatment.

In TCM syndrome differentiation, compared with before treatment,
* The integral qi deficiency syndrome, blood deficiency syndrome and yin deficiency syndrome were decreased, while the integrals for dampness heat syndrome and the turbid-toxin syndrome were increased by the treatment of AAM.

* AAM treatment exerted no obvious difference in all indices except the integral for hypertensive renal damage patients of yin deficiency syndrome.

* The SCr decreasing percent was 19.82% +/- 8.30% for patients of non-qi-blood deficiency syndrome compared to 5.24% +/- 10.75% for patients of QBDS.

* More precisely, the integral differences of qi deficiency and blood deficiency were obviously higher in patients of QBDS, when compared with patients of non-QBDS (P < 0.05).

Based on the results, researchers suggest, "AAM could improve the renal function of CKD patients, elevate their ALB levels, and ameliorate associated qi deficiency syndrome, blood deficiency syndrome, and yin deficiency syndrome, especially for CKD patients of QBDS".

Taken altogether, Dandelion may be considered a remedy for the treatment of CKD in both conventional and TCM medicines, pending to the confirmation of the larger sample size and multicenter human study.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) [Therapeutic effect of Astragalus and Angelica mixture on the renal function and TCM syndrome factors in treating stage 3 and 4 chronic kidney disease patients].[Article in Chinese] by Li S, Yin XX, Su T, Cao C, Li X, Rao XR, Li X. (PubMed)

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