Cancer is the class of diseases associated with the growth of the cells disorderly and uncontrollably due to the alternation of DNA.
Most cases of cancer begin in the cells on the surface of the inner lining tissues of the organ or gland. At the early stage, most cancers are asymptomatic.
However, at the advanced stage, most cancers not can induce common symptoms such as gastrointestinal discomforts, unintended weight loss, loss of appetite and fatigue but also localized symptoms depending on the affected tissues and organs.
Cancers at this stage also can travel a distance away from the original site to induce secondary metastasis.
According to the statistics provided by the American cancer society, in 2018,1,735,350 new cases were diagnosed, representing more than 4,700 new cancer diagnoses each day.
The lifetime probability of being diagnosed with cancer is 39.7% for men and 37.6% for women.
Compared to all cancers, lung, breast, prostate, and colorectal cancers are the most common cancer in the US.
Some cases of cancer are treated by radiotherapy which uses high doses of radiation to kill cancer cells and shrink tumors.
Radiotherapy has been found to induce certain adverse effects in cancer treatment.
For example, osteoradionecrosis is a condition associated with bone death due to exposure to radiation or radiation treatment.
The death of bone cells is a result of radiation induce-damage of the blood vessel that supplies the nutrients to the bone.
Osteoradionecrosis is a rare side effect occurred sometime after radiation therapy has ended. The complication usually occurs in the lower jaw or mandible.
The death of bone cells is a result of radiation induce-damage of the blood vessel that supplies the nutrients to the bone.
Osteoradionecrosis is a rare side effect occurred sometime after radiation therapy has ended. The complication usually occurs in the lower jaw or mandible.
On finding a natural ingredient for the protection against radiation-induced adverse effects, scientists examined the radio-modulatory efficacy of aqueous root extract of I. racemosa.
Elecampane, also known as Horse-heal (Inula helenium) is a perennial composite plant, genus nulla, belonging to Asteraceae, native to Southern Europe, and Asia.
Elecampane, also known as Horse-heal (Inula helenium) is a perennial composite plant, genus nulla, belonging to Asteraceae, native to Southern Europe, and Asia.
The plant has been used in traditional and herbal medicine in treating bronchitis or emphysema, night sweats, pulmonary tuberculosis, irritating cough, catarrhal discharges, etc.
According to the tested analysis of normal kidney epithelium cells that were treated with the extract (50-200 μg/ml) and exposed to 3 Gy of γ-radiation, while C57BL/6 mice were administered with extract (300-600 mg/kg BW) intraperitoneally prior to exposure to 7.5 Gy of γ-radiation,
* The administration of the extract (30 min and 1 h) prior to radiation exposure improved the NKE cell survival.
* The proteins associated with the production of antioxidant enzymes were significantly induced by the administration of the extract observed by the increase of Nrf2 protein levels at 7 h and HO-1 and NOQ1 protein at 24 h.
Based on the results, researchers suggest, "The aqueous extract of roots of I. racemosa enhanced the survival of irradiated NKE cells and rescued C57BL/6 mice against WBI-induced mortality.".
Taken altogether, Dandelion may be considered a remedy for the protection of radio-side effects, pending to the confirmation of the larger sample size and multicenter human study.
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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Role of Nrf2-antioxidant in radioprotection by root extract of Inula racemosa by Mohan S1, Gupta D. (PubMed)
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