Sunday, 12 May 2019

Whole Food Ginger, the best for the Treatment of Diarrhea

By Kyle J. Norton


 Diarrhea, a very common condition found in the infants and children of the third world countries is a gastrointestinal disorder characterized by frequent(3 or 4 times) loose, watery stools a day.

Acute diarrhea, healed by its own is a common problem caused by viruses that may last in a few days. Most common causes of acute diarrhea are rotavirus in children and norovirus in adults.

Persistent diarrhea lasts more than 4 weeks is considered chronic diarrhea.

Chronic diarrhea is a medical condition caused by impaired digestion of fats due to low production of the pancreatic enzymes and impaired absorption of fats due to small intestinal disease, including lactose, sorbitol, and fructose intolerance and irritable bowel syndrome (IBS).

Certain medications such as antibiotics, dietary changes, infected by bacteria or virus are some of the most common factors associated with an increased risk of diarrhea.

The cause of diarrhea normally can be found after a stool sample test.

The American College of Gastroenterology suggested unless the cause is found, patients with diarrhea should avoid dehydration and milk and dairy products should be avoided for 24 to 48 hours.

Patients with bloody diarrhea or severe abdominal pain or diarrhea lasting more than 48 hours.should check with their doctors immediately.


Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.

The root has been used in traditional and Chinese medicine for the treatment of dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.

In the urgency to find a natural ingredient with low cost for the treatment of diarrhea in the third world countries, where diarrhea is common and anti-diarrhea medicines are scarce, and to prevent the disease induced-infant death, researchers examined the ginger effect on Enterotoxigenic Escherichia coli heat-labile enterotoxin (LT)-induced diarrhea.

In a mice study, ginger significantly blocked the binding of LT to cell-surface receptor G M1, resulting in the inhibition of fluid accumulation in the closed ileal loops of mice and production of diarrhea.

Further analysis of the chemical constituents in the ginger, researchers found that zingerone (vanillylacetone) was the active constituent responsible for the antidiarrheal efficacy of ginger.

Dr. Chen JC, the lead scientist said, "our findings provide evidence that ginger and its derivatives may be effective herbal supplements for the clinical treatment of enterotoxigenic Escherichia coli diarrhea".

In order to clarify the ginger anti-diarrhea activity, researchers at the Kyoto Pharmaceutical University evaluated the acetone extract of ginger at 75 mg/kg p.o against the onset of the condition.

Oral administration of acetone extract of ginger at 75 mg/kg p.o., significantly inhibited 5-HT induced diarrhea in mice model.

The antibacterial effects of ginger against diarrhea were attributed to the presence of [6]-shogoal, [6]-dehydrogingerdione, [8]- and [10]-gingerol.

Take all together, ginger may be considered a functional alternative for the treatment of diarrhea, pending to the confirmation of large sample size and multicenter human study.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma ISSN 0975-6299.

Sources
(1) Ginger and its bioactive component inhibit enterotoxigenic Escherichia coli heat-labile enterotoxin-induced diarrhea in mice by Chen JC1, Huang LJ, Wu SL, Kuo SC, Ho TY, Hsiang CY. (PubMed)
(2) [The effect of ginger on serotonin induced hypothermia and diarrhea].[Article in Japanese] by Huang Q1, Matsuda H, Sakai K, Yamahara J, Tamai Y. (PubMed)



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