Monday, 6 May 2019

Topical Turmeric, the Best for the Prevention and Treatment Vitiligo

By Kyle J. Norton

Vitiligo is a condition of skin discolor disease caused by the destruction of pigment cells and melanocytes of the skin.

The condition in most cases is localized. However, in some patients, the disease also can affect several different areas on the body.

Symptoms of vitiligo are associated with the loss of skin color, or white, and patches of skin.

The exact cause of vitiligo is unknown, however, some researchers suggested that the disease may be caused by the immune overreaction that mistakenly attacks and destroys certain cells within the body.

Epidemiologically, people in the younger age group before the age of 40 are at most risk of vitiligo.
According to the statistics, over 50% of vitiligo are found in patients who are 20 and younger.

The condition has been found to induce emotional and psychological issues to patients, even the condition does not cause pain or health problems.

As of today, researchers do not know how to prevent disease onset. Most medications for the treatment of vitiligo including creams that control inflammation, combining psoralen and light therapy are focusing on reducing the severity of the condition and improve the quality of life.

If all noninvasive treatments fail, surgery may be necessary.

Turmeric is a perennial plant in the genus Curcuma, belongings to the family Zingiberaceae, native to tropical South Asia.

The herb has been used in traditional medicine as anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and to treat flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.

On finding a natural compound for the treatment of vitiligo, researchers examined the curcumin effect on the pigment cells of the skin, melanocytes.

Injection of Cucumis melo extract showed to exhibit the production of antioxidant by the host in blocking the effect of free radical in the induction of skin oxidative stress.

Topical preparation, containing Cucumis melo superoxide dismutase (SOD) and catalase, demonstrated a potential effect in the treatment of vitiligo.

Natural UV or artificial narrowband UVB treatment or phototherapy displayed significant protection against pigment damage, similar to those of turmeric topical preparation.

Additionally, the topical gel according to the repigmentation rate recorded exerted a similar effect compared to the patients treated only with the phototherapy with adverse effects.

Moreover, the topical formulation, containing phenylalanine, Cucumis melo extract, and acetylcysteine showed a more promising result combined with nb - UVB target phototherapy.

Based on the findings, turmeric used along with or combined with other conventional medicine may be considered remedies for the prevention and treatment of vitiligo pending to the confirmation of the larger sample size and multicenter human study.

Intake of turmeric in the form of supplement should be taken with extreme care to prevent overdose acute liver toxicity.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

(1) Herbal Compounds for the Treatment of Vitiligo: A Review by Serena Gianfaldoni,1,* Uwe Wollina,2 Michael Tirant,3 Georgi Tchernev,4 Jacopo Lotti,5Francesca Satolli,6 Miriam Rovesti,6 Katlein Fran├ža,7 and Torello Lotti. (PMC)

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