Saturday 16 September 2017

Herbal Therapy: Chaste tree berry, the Anti Prostate Cancer Whole Herb

Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


The use of plants for healing purposes has been predated long before the existence of  modern medicine. Herbal plants have formed a fundamental source for conventional medicine in discovery of single ingredient medication, including aspirin (from willow bark), quinine (from cinchona bark), and morphine (from the opium poppy)......

Believe or not, Chaste tree berry is shown to process a significant anti prostate cancer activity, a study of a renowned University proposed.

Chaste tree berry is a species of Vitex agnus-castus, genus Vitex, belonging to the family Lamiaceae, native to the Mediterranean region, used in herbal medicine for thousands of year as anaphrodisiac herb and considered as Queen herb in treating menstrual problems and discomforts.

Prostate cancer is a condition in which the cells of prostate has become cancerous. Most prostate cancers are slow growing and enlarged prostate and prostate cancer may be detected during the Physical (rectum) exams.

According to the University of Basel, extracts of Vitex agnus-castus fruits (VACF) inhibited human prostate epithelial cell lines (BPH-1, LNCaP, PC-3) in different stages of androgen responsiveness, through its antiproliferative activity in induced apoptosis and potential cytotoxicity.

Dr. Weisskopf M, the lead author said, "The extract inhibited proliferation of all three cell lines in a concentration-dependent manner with IC (50) values below 10 microg/mL after treatment for 48 h. Cell cycle analysis and DNA fragmentation assays suggest that part of the cells were undergoing apoptosis" and " 

Furthermore, the extract may be useful for the prevention and/or treatment of benign prostatic hyperplasia.

Other study in proposal of five herbal supplements, designated FB, FM, PP, HF and FBL101, containing different combinations of various natural herbs such as licorice, black cohosh, Dong Quai, false unicorn and vitex berry root extracts, found that the five herbal supplements inhibited PC3 tumor growth by 53%, 75%, 80%, 81% and 87%, respectively without altering plasma testosterone levels relative to the untreated control.

Supplement of vitex berry root extracts significantly reduced VEGF levels, a product produced by cancer cells in large quantities, in mediation of angiogenesis through blocking the forming of new blood vessels in PC3 and CWR22R tumors,

There is no doubt that Chaste tree berry and its supplement may be used as preventive and therapeutic agents in reduced risk and treatment of prostate cancer. But intake of large amount should only be given by herbalist to prevent toxicity.




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Sources
(1) A Vitex agnus-castus extract inhibits cell growth and induces apoptosis in prostate epithelial cell lines by Weisskopf M1, Schaffner W, Jundt G, Sulser T, Wyler S, Tullberg-Reinert H.(PubMed)
(2) Antitumor activity of herbal supplements in human prostate cancer xenografts implanted in immunodeficient mice by Ng SS1, Figg WD.(PubMed)

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