Saturday, 30 September 2017

Food Therapy: Kidney bean, the Whole Food in Reduced Risk and Treatment of Leukemia

Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international jourenal Pharma and Bio science, ISSN 0975-6299.

If you expect that food and herbal medicine will ease the symptoms of your illness immediately after few day of treatment, you will be disappointed. Symptoms of the diseases can only be eased gradually, depending to stages of the treatment which directly address to the cause of the disease.

Intake of cooked Dried red kidney beans regularly may reduce risk and delay progression risk of Leukemia, a renowned institute study proposed.

Kidney bean is popular food, with  kidney shape, strong flavor and color in reddish brown in nature, used often as an excellent dietary selection because of enormous health benefits with a good source of protein and minerals.

Leukemia is condition of abnormal increase of white blood cells produced by the bone marrow and/or the lymphatic system. Depending to the malignant granulocytes or lymphocytes, leukemia is classified into myelogenous or lymphoblastic leukemia.

Chemical compound purified from dried kidney beans, namely, 7.3-kDa antifungal peptide, used mainly for treatment of fungal overgrowth, showed to suppress the spread of leukemia L1210 cells with an half concentration of 5.2±0.4 µM and 7.6±0.6 µM, according to the China Agricultural University.

Dr. Ma DZ, the lead researcher said, "(the antifungal peptide isolated from dried Nepalese large red beans) exerted an antiproliferative action on L1210 leukemia cells with an an half concentration of high doses at 15 and 60 microM, respectively".

Other chemical compound, L-asparaginaseenzyme, isolated from Phaseolus vulgaris seeds also enhanced anti-proliferative effect on ALL cells according to the WST-8 cell viability assay kit.

Furthermore, treatment of L-asparaginaseenzyme also involved significant in induced early apoptosis in acute Lymphoblastic leukemia in test subjects jn vivo.

According to the joint study lead by the King Abdulaziz University, the efficacy of novel L-asparaginaseenzyme, isolated from Phaseolus vulgaris seeds (P-Asp) in mice study showed that  mice treated with P-Asp had less distinct allergenic responses by immune system in expression of higher risk of carcinogens and reduced treatment effects.

There is no doubt that kidney beans may be a potential health benefit in targeting the risk of  Leukemia in early stage and prevent the progression of the cancer through anti-proliferative and induced tumors cell death.

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(1) An antifungal peptide with antiproliferative activity toward tumor cells from red kidney beans by Li M1, Wang H, Ng TB.(PubMed)
(2) A peptide with potent antifungal and antiproliferative activities from Nepalese large red beans by Ma DZ1, Wang HX, Ng TB.(PubMed)
(3) Trypsin isoinhibitors with antiproliferative activity toward leukemia cells from Phaseolus vulgaris cv "White Cloud Bean" by Sun J1, Wang H, Ng TB.(PubMed)
(4) Isolation and Characterization of a Phaseolus vulgaris Trypsin Inhibitor with Antiproliferative Activity on Leukemia and Lymphoma Cells by Li M1,2, Liu Q3, Cui Y4, Li D5, Wang H6, Ng TB7.(PubMed)

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