Monday, 4 September 2017

Food Therapy: Asparagus, the Natural Whole Food with Antidiarrhoeal effects

By Kyle J. Norton

Whole food(herbal medicine) used as medical treatment,  linking health benefits in prevention, management and treatment of diseases has induced much interests in today renowned scientists.
But many researchers have raised question of herbal quality, because geographic differences, time of grown and harvest, etc. may effect their's potency. I do believe, these questions can only be answered by experience herbalists.

Recent study by the renowned institute suggested that Asparagus racemosus processed an antidiarrheal effect through ameliorating the discharge from the bowel.

Asparagus is a flowering plant belong to species the genus Asparagus, native to the western coasts of northern Spain, north to Ireland, Great Britain, and northwest Germany, northern Africa and western Asia, used from early times as a vegetable and medicine, because of its delicate flavour and diuretic properties.

Diarrhoea is condition of frequent discharge of feces in liquid form.

According to the K.P. College of Pharmacy, Asparagus racemosus wild root extract used traditional herbal medicine exerted the antidiarrhoeal potency against several experimental models of diarrhoea in model animals, similar to those of conventional medicine such as loperamide.

This efficacy is attributed to the root extracts in mediation of Prostaglandin E2 (PGE2), a principal hormone in expression of inflammatory diseases.
Dr. Venkatesan N. the lead researcher said, "The plant extracts showed significant (P < 0.05) inhibitor activity against castor oil induced diarrhoea and PGE2 induced enteropooling in rats when tested at 200 mg/kg. Both extracts also showed significant (P < 0.001) reduction in gastrointestinal motility ".

In support of the above study, the test of animal model on Alpha-2 blocker (see alpha(2)-adrenoceptor) experimentally-induced diarrhoea and ulceration, showed a positive effect of methanolic extract of Asparagus pubescens root in reduced significantly intestinal propulsive movement, and intestinal fluid accumulation in (500-1500 mg/kg) in dose-dependent manner.

In fact, the antidiarrhoeal effect of asparagus may be a result of modulated the expression of alpha(2)-adrenoceptor in regulated vascular smooth muscle  contraction and vasoconstriction though Prostaglandin E2 (PGE2) modification. But further studies may be necessary to validate this potency.

(1) Anti-diarrhoeal potential of Asparagus racemosus wild root extracts in laboratory animals by Venkatesan N1, Thiyagarajan V, Narayanan S, Arul A, Raja S, Vijaya Kumar SG, Rajarajan T, Perianayagam JB.(PubMed)
(2) Antidiarrhoeal and antiulcerogenic effects of methanolic extract of Asparagus pubescens root in rats by Nwafor PA1, Okwuasaba FK, Binda LG.(PubMed)

Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

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