Monday, 28 August 2017

Herbal Therapy: Green Tea, in Reduced Risk of Early Onset and Progression of Dementia

Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
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Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

People who turn to herbal Medicine for treatment of disease in avoidance of adverse effect induced by conventional medicine must be patient as the alternative treatment can only ease symptoms gradually, depending to stage of the treatment which directly address to the cause.

Dementia is the loss of mental ability that is severe enough to interfere with people's every life and Alzheimer's disease is the most common type of dementia in aging people. About 5-8% of all people over the age of 65 have some form of dementia, and this number doubles every five years above that age.

Green tea may be used as functional food for prevention of early onset and treatment of dementia due to aging progression, a renowned institute study suggested

Green tea, a precious drink processes numbers of health benefit known to almost everyone in Asia and Western world. However, as yin in nature herbal medicine ,or food, long term injection of large amounts may obstruct the balance of yin-yang, induced "yin excessive syndrome" or "yang vacuity syndrome", according to traditional Chinese medicine's Yin-Yang theory. Adding a slice of ginger will do the neutralization trick.

In the 5.7-year prospective cohort study, using a questionnaire, information on daily green tea consumption and other lifestyle factors collected from elderly Japanese individuals aged 65 years or more, green tea consumption is associated to reduced risk of dementia with a incidence of occurrent rate of 8.7%.

Furthermore, in the intracerebroventricular (ICV) infusion of streptozotocin (STZ) animal model explicted chronic brain dysfunction involved long-term and progressive deficits in learning, memory, and cognitive behavior, along with a permanent and ongoing cerebral energy deficit, mice treated with green tea EGCG at a dose of 10mg/kg/day for 4 weeks, showed a sigificant improvement in reduced oxidative stress parameter against production of inflammatory and free radical expression.

These inhibitions can be seen in the diminished AChE activity, glutathione peroxidase activity as well as NO metabolites, and reactive oxygen species contents

More importantly, the enhanced antioxidants status induced neuroprotective effect is result of EGCG injection in ameliorated  inflammatory and free radical causes of cell death in brain of treated mice.

Dr. Tomata Y, the lead author of the study said, "The lower risk of incident dementia was consistent even after selecting participants who did not have subjective memory complaints at the baseline."

More explicitly, in the finding of a natural food for reverse or delay of risk factors of dementia and AD, vascular, metabolic, and lifestyle-related factors involved development of dementia and late-life cognitive disorders, green tea with high amount of caffeine stimulate the psychoactive effects in attenuated cognitive impairment/decline and dementia through heightened alertness and arousal and improvement of cognitive performance.

Promisingly, such results have been proposed by several cross-sectional and longitudinal population-based studies, particular in patients with mild cognitive impairment and progression to dementia.

There is no doubt that green tea may be considered as a function foods for reduced risk of early onset and delay progression of dementia, but longer follow-up periods are necessary before the use of green tea can open new ways for diet-related prevention and treatment of dementia.

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Sources
(1) Green Tea Consumption and the Risk of Incident Dementia in Elderly Japanese: The Ohsaki Cohort 2006 Study by Tomata Y1, Sugiyama K2, Kaiho Y2, Honkura K2, Watanabe T2, Zhang S2, Sugawara Y2, Tsuji I2(PubMed)
(2) Green tea (-)epigallocatechin-3-gallate reverses oxidative stress and reduces acetylcholinesterase activity in a streptozotocin-induced model of dementia by Biasibetti R1, Tramontina AC, Costa AP, Dutra MF, Quincozes-Santos A, Nardin P, Bernardi CL, Wartchow KM, Lunardi PS, Gonçalves CA.(PubMed)
(3) Coffee, tea, and caffeine consumption and prevention of late-life cognitive decline and dementia: a systematic review by Panza F1, Solfrizzi V, Barulli MR, Bonfiglio C, Guerra V, Osella A, Seripa D, SabbĂ  C, Pilotto A, Logroscino G.(PubMed)

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