Herbal Therapy:, Andrographis aniculata, The Best Whole Herb Medicine for Relieving Symptoms and Treatment of Upper Respiratory Tract Infection

Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
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Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Whole food(herbal medicine) used as medical treatment, linking health benefits in prevention, management and treatment of diseases has induced much interests in today renowned scientists.
But many researchers have raised question of herbal quality, because geographic differences, time of grown and harvest, etc. may effect their's potency. I do believe, these questions can only be answered by experience herbalists.
Andrographis paniculata may be one of the best herb for prevention and treatment of  Andrographis aniculata upper respiratory tract infection caused by spreading from person to person in respiratory droplets through sneezing or coughing of individual infected with the virus, a renowned institute study suggested.

Upper respiratory tract infections are the infection of the airway above the glottis or vocal cords, including the nose, sinuses, pharynx, and larynx,  tonsillitis, pharyngitis, laryngitis, sinusitis, otitis media, etc,.

Andrographis paniculata is also known as Andrographis is a herbaceous plant, genus Andrographis, belonging to the family Acanthaceae, native to India and Sri Lanka, used in traditional Siddha and Ayurvedic in treating the common cold, flu, upper respiratory infections, infectious diseases, diarrhea, dysentery, cholera, pneumonia,....

According to the joint study lead by the ilpakorn University in the review of the existence data of the literature and meta-analysis of randomized controlled trials, Andrographis paniculata exerted a strong implication n the symptomatic treatment of uncomplicated upper respiratory tract infection by measuring the reduction in symptom severity scores.

In a total of 433 patients reported in three trials included in the statistical analysis, patient treated with combination of Andrographis aniculata, Acanthopanax senticosus and Andrographis aniculata alone exhibited a significant improvement of 2.13 points and 10.85 points on the symptom severity score in compared placebo.

Dr. Poolsup N, the lead author said, "A. paniculata extract alone or in combination with A. senticosus extract may be more effective than placebo and may be an appropriate alternative treatment of uncomplicated acute upper respiratory tract infection".

Furthermore, in the review to prevent the over-prescription of antibiotics and absence from work due to acute upper respiratory tract infection, A. paniculata is found to be more superior to placebo in alleviating the subjective symptoms of uncomplicated upper respiratory tract infection.
 The study also indicated that all review trials scored at least three, out of a maximum of five, for methodological quality on the Jadad scale.

More importantly, the efficacy of A. paniculata  in relieving symptoms of uncomplicated upper respiratory tract infection only induced generally mild and infrequent adverse effects.

Further in supporting the Andrographis aniculata's anti upper respiratory tract infection property, a total of 223 patients of both sexes randomized in two groups which received either KalmCold (200 mg/day) or placebo in a double blind manner showed a promising result of A. paniculata in ameliorating symptoms of cough, expectoration, nasal discharge, headache, fever, sore throat, earache, malaise/fatigue and sleep disturbance from day 1 to day 3 of treatment in comparison to placebo group.

Additionally, The overall efficacy of extract of Andrographis paniculata was found to be 2.1 times (52.7%) higher than placebo.

Taking together, there is no doubt that Andrographis aniculata has a potency used as therapeutic agent for relieving symptoms and treatment of  upper respiratory tract infection but intake of large doses and long term intake should be taken with care.

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Sources
(1) Andrographis paniculata in the symptomatic treatment of uncomplicated upperrespiratory tract infection: systematic review of randomized controlled trials by Poolsup N1, Suthisisang C, Prathanturarug S, Asawamekin A, Chanchareon U.(PubMed)
(2) Andrographis paniculata in the treatment of upper respiratory tract infections: a systematic review of safety and efficacy by Coon JT1, Ernst E.(PubMed)
(3) A randomized double blind placebo controlled clinical evaluation of extract of Andrographis paniculata (KalmCold) in patients with uncomplicated upperrespiratory tract infection by Saxena RC1, Singh R, Kumar P, Yadav SC, Negi MP, Saxena VS, Joshua AJ, Vijayabalaji V, Goudar KS, Venkateshwarlu K, Amit A.(PubMed)