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Friday, 20 May 2016

Most Common Disease of50plus: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs)- Gout - Treatment In TCM formula Modified Simiaowan (MSW)

Kyle J. Norton (Scholar and Master of Nutrients, all right reserved)Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
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Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. According to a community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home, musculoskeletal pain was reported by 57% of those interviewed(*).

Types of Musculo-Skeletal disorders in elder

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia

                                          Gout

Gout mostly effected one joint is an acute and recurrent condition of arthritis as a result of uric acid building up in blood, inducing joint inflammation.


              


                                              Treatments

B. Other research and studied formulas
1. Modified Simiaowan (MSW)
Modified Simiaowan (MSW), a TCM formula is widely used as a clinically medication formula for its efficiency in treating gouty diseases. According to the joint study led by the Nanjing University of Chinese Medicine, the formula targeted related pathways involving gouty diseases through inhibited pro inflammatory cytokines and uric acid synthetase or transporters, via heat-clearing and dampness-eliminating herbs in MSW physicochemical properties(284).
Dr. Shi L and colleagues said, "MSW could significantly prevent the paw swelling and neutrophil infiltration induced by intra-articular MSU injection in rats. MSW also showed potent analgesic effects at (5.0, 10, and 20 g/kg body weight) in acetic acid-induced mice depending on the dosage" in 
gouty arthritis mice(285).

(284) Shu Feng Huo Xue Tang by (Root down US)
(284) A network pharmacology approach to determine active ingredients and rationality of herb combinations of Modified-Simiaowan for treatment of gout.by Zhao F1, Guochun L2, Yang Y3, Shi L1, Xu L1, Yin L4.(PubMed)
(285) Suppressive effect of modified Simiaowan on experimental gouty arthritis: an in vivo and in vitro study by Shi L1, Xu L, Yang Y, Song H, Pan H, Yin L(PubMed)