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Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Musculoskeletal disorders (MSDs) are medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. According to a community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home, musculoskeletal pain was reported by 57% of those interviewed(*).
Types of Musculo-Skeletal disorders in elder
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
7. Low back pain
Gout mostly effected one joint is an acute and recurrent condition of arthritis as a result of uric acid building up in blood, inducing joint inflammation.
A. In conventional medicine perspective
Corticosteroids, also known as terpod hormone, are an anti-inflammatory medicine prescribed for a wide range of conditions in reduced inflammation and suppressed the immune system.a. According to study, systemic corticosteroids could be used in severe poly articular flares(246). Anti-IL1 should provide a therapeutic alternative for severe cortico dependent gout with tophus(246). To prevent acute flares and reduce tophus volume, uric acid serum level should be reduced and maintained below 60mg/L (360μmol/L). The medicine is also considered as one of most frequent prescription for treatment of gout patients(247).
b. Side effects are not limit to
b.1. Stomach irritation
b.2. Rapid heartbeat
b.5. A metallic taste in the mouth
According to the University of Alberta, application of glucocorticoids has shown to induce pressure in the cardiovascular system include dyslipidemia and hypertension(249) as well as exhibiting certain psychiatric symptoms, including depression(250) and psychiatric complications such as psychosis, mania, hypomania, depression, apathy, anxiety, panic, depersonalization, delirium, confusion, hallucinations, delusions, paranoia, cognitive impairment and dementia(251).
Dr. Mitra R said, "Glucocorticoid (GC) exposure is the most common etiology of drug-induced (secondary) osteoporosis." and "GC stimulates osteoclast-mediated bone resorption and reduces osteoblast-mediated bone formation, which results in increased overall net bone resorption'(248).
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