Sunday, 15 May 2016

Most Common Disease of50plus: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs)- Gout - Treatment In Herbal medicine - Alfalfa

Kyle J. Norton (Scholar and Master of Nutrients, all right reserved)Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
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Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. According to a community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home, musculoskeletal pain was reported by 57% of those interviewed(*).

Types of Musculo-Skeletal disorders in elder

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia


Gout mostly effected one joint is an acute and recurrent condition of arthritis as a result of uric acid building up in blood, inducing joint inflammation.



In herbal medicine perspective
3. Alfalfa
Alfalfa is a flowering plant in the genus Medicago, belongings to the family Fabaceae, cultivated all over the world as hay for cattle feeding. The leaves, sprouts, and seeds has been used in traditional medicine over thousands of year to treat high cholesterol, asthma, osteoarthritis, rheumatoid arthritis, diabetes, enhance digestive system, bleeding disorder, kidney and urinary tract infection, etc.

In the article by By jeffwend, the author wrote that Alfalfa can help to increase uric acid levels in the urine which can help reduce the amount of uric acid available to crystallize(270), probably due to the effectiveness of ethyl acetate extracts isolated from the herb in ameliorated production of pro-inflammatory cytokines and alleviate acute inflammatory hazards(271).
Dr. Ferrari FC and colleagues at the Universidade Federal de Ouro Preto, in the investigation of Leaves infusion of Pimenta pseudocaryophyllus (Gomes) Landrum, expressed the inhibition of ethyl acetate extracts in anti-hyperuricemic effects through uricosuric effects and inhibition of xanthine oxidase throughits anti-inflammatory property(272).
The Universidade other study also insisted, "The ethyl acetate, methanolic and aqueous extracts of Sparattosperma leucanthum showed significant results on evaluated models and therefore may be important agents for the treatment of gouty arthritis and hyperuricemia"(273).

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(270) Alfalfa For Gout, Updated on August 24, 2012(Treat and prevent gout with Alfalfa Tablets)
(271) Ethyl acetate extracts of alfalfa (Medicago sativa L.) sprouts inhibit lipopolysaccharide-induced inflammation in vitro and in vivo by Hong YH1, Chao WW, Chen ML, Lin BF.(PubMed)
(272) Effects of Pimenta pseudocaryophyllus extracts on gout: Anti-inflammatory activity and anti-hyperuricemic effect through xantine oxidase and uricosuric action by Ferrari FC1, Lemos Lima Rde C1, Schimith Ferraz Filha Z1, Barros CH1, de Paula Michel Araújo MC1, Antunes Saúde-Guimarães D2.(PubMed)
(273) Effects of extracts of leaves from Sparattosperma leucanthum on hyperuricemia and gouty arthritis by Lemos Lima Rde C1, Ferrari FC1, de Souza MR1, de Sá Pereira BM1, de Paula CA1, Saúde-Guimarães DA2.(PubMed)