Wednesday, 25 May 2016

Most Common Disease of 50plus: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs) - Fibromyalgia - The Risk factors

Kyle J. Norton (Scholar)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
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Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are  medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed(1).

      Types of Musculo-Skeletal disorders in elder

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia


Fibromyalgia, according to the American College of Rheumatology 1990 Criteria for the Classification of Fibromyalgia in the newly proposed criteria for the classification of fibromyalgia are 1) widespread pain in combination with 2) tenderness at 11 or more of the 18 specific tender point sites(a) as a result in responding to pressure.

                            The Risk factors

B. Risk factors
1. Gender
If you are women, you are at higher risk than men to develop Fibromyalgia. According to the Katedra Propedeutyki Pediatrii i Klinika Immunologii Wieku Rozwojowego Akademii Medycznej we Wrocławiu, fibromyalgia may occur at any age, even in childhood, is much more common in women than in men(23).
Dr. Reiffenberger DH and Amundson LH said, "Fibromyalgia syndrome includes symptoms of widespread, chronic musculoskeletal aching and stiffness and soft tissue tender points. It is frequently accompanied by fatigue and sleep disturbance. Fibromyalgia is more common in women than in men, and it occurs at a mean age of 49 years"(24).
2. Family history
 It appears that there are factors in this personality trait that are hereditary and that may contribute to the development of FM(25), including psychological distress(26), familial history of depression(27),.... According to Dr. Hudson JI and colleagues, said,  "the familial prevalence of major affective disorder were significantly higher in the fibromyalgia patients than the rheumatoid arthritis patients":(28).

3. Environment factors
Environmental susceptibility may be the possible causes of Fibromyalgia(29) such as chronic stress(30)

4. Chronic illness
There is a believe that certain illness are associated to the increased risk of Fibromyalgia(35) such as diseases of infection(33)(34),  and Chronic fatigue syndrome (CFS)(32), affecting the quality of work and social life, according to Dr. Asbring P.(31).

5. Etc.

(23) [Fibromyalgia syndrome--pathogenesis, diagnosis, and treatment problems].[Article in Polish]
 by Polańska B1.(PubMed)
(24) Fibromyalgia syndrome: a review by Reiffenberger DH1, Amundson LH.(PubMed)
(25) Differences in the personality profile of fibromyalgia patients and their relatives with and without fibromyalgia by Glazer Y1, Buskila D, Cohen H, Ebstein RP, Neumann L.(PubMed)
(26) Are psychological distress symptoms different in fibromyalgia patients compared to relatives with and withoutfibromyalgia? by Glazer Y1, Cohen H, Buskila D, Ebstein RP, Glotser L, Neumann(PubMed) 
(27) Self-reported depression, familial history of depression and fibromyalgia (FM), and psychological distress in patients with FM by Offenbaecher M1, Glatzeder K, Ackenheil M.(PubMed)
(28) Fibromyalgia and major affective disorder: a controlled phenomenology and family history study by Hudson JI, Hudson MS, Pliner LF, Goldenberg DL, Pope HG Jr.(PubMed)
(29)  Sleep disorders and fibromyalgia. by Roizenblatt S1, Neto NS, Tufik S.(PubMed)
(30) Vulnerability to traumatic stress in fibromyalgia patients: 19 month follow-up after the great East Japan disaster by Usui C, Hatta K, Aratani S, Yagishita N, Nishioka K, Okamura S, Itoh K, Yamano Y, Nakamura H, Asukai N, Nakajima T, Nishioka K.(PubMed)
(31) Chronic illness -- a disruption in life: identity-transformation among women with chronic fatigue syndrome andfibromyalgia by Asbring P1.(PubMed)

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