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Thursday, 26 May 2016

Most Common Disease of 50plus: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs) - Fibromyalgia - The Complications

Kyle J. Norton (Scholar)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are  medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed(1).

      Types of Musculo-Skeletal disorders in elder

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia

                                                      Fibromyalgia

Fibromyalgia, according to the American College of Rheumatology 1990 Criteria for the Classification of Fibromyalgia in the newly proposed criteria for the classification of fibromyalgia are 1) widespread pain in combination with 2) tenderness at 11 or more of the 18 specific tender point sites(a) as a result in responding to pressure.

                              The  Complications

1. Negative impact in relationships
Fibromyalgia can result in a substantial negative impact on important relationships with family and close friends(36), according to the survey of 6,126 adults, lts diagnosed with fibromyalgia, including mildly to moderately damaged relationship(s) with their spouse(s)/partner(s) or contributed to a break-up with a spouse or partner.(35).
Dr. Yener M and colleagues at the joint study led by the Suleyman Demirel University, said, "FM can cause deterioration of emotional status and lead to sexual dysfunction. Also, psychological status could be affected in spouses of women with FM at reproductive age, and the severity of depression of their spouses was significantly correlated to that of women with FM"(36). further more, fibromyalgia also found to induce sexual dysfunction and quality of life of the spouse as well, according to the Harran University Medical School study(37)

2. Psychological problem
According to the study by Monash University and Monash Medical Centre in comparison between FM patients and healthy individuals found significant difeferences in control (Perceived Control of Internal States Scale and Mastery S.cale), patients with fibromyalgia also are associated to both high and low levels of stress, mood, pain, and fatigue(38).
Dr. Malin K Dr. Littlejohn GO said, "Stress in females with fibromyalgia associates with both key symptoms and a range of relevant psychological variables. Stress appears to have a major role in modulating several key 'up-stream' processes in fibromyalgia"(39). Spouse of reproductive age women are also experience to enormous amount of psychological problem, including anxiety and depression(40).
3. Pain disability
Fibromyalgia syndrome (FMS) has found to exhibited pain disability but  differences in genders
(41). Women with fibromyalgia reported higher intensity of pain, tender point count, and depression than men(41). According to the, manual therapy protocol was effective to improve pain intensity, reduce pressure pain sensitivity, with significant impact of FMS symptoms, sleep quality, and depressive symptoms, particular in women(42).
In fact, the joint study led by the McGill University Health Centre suggested, the risk of disability of patients with fibromyalgia is substantial high in Western World(one out of three)(43).

4. Impaired functionality, and impact on the quality of life
Women with Fibromyalgia also showed a positive correlation of  impaired functionality(46), and impact on the quality of life in comparison to women without(44). According to the Pamukkale University Medical School, in the survey of 51 patients with FMS and 41 control subjects, patients with fibromyalgia reported higher in impaired functional status(46) and diminished quality of life than control(45).

5. Fall risk and Postural control deficits
There were significant relationships between fall risk  in patients with Fibromyalgia. Worse postural performance and fall risk found in the fibromyalgia patients may be resulted of the sleep quality in the last 24 h and level of fatigue(47). According to the Oregon Health & Science University, objective sensory deficits on dynamic posturography(48) and impaired balance(49)
 is also found consistently to associate to middle-aged FM patients inducing fall rates.
The reduced fall risk and postural control deficits probably can be achieved through  combine balance training with exercise and cognitive training(50).

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References
(35) Chronic widespread pain and fibromyalgia: could there be some relationships with infections and vaccinations? by Cassisi G1, Sarzi-Puttini P, Cazzola M.(PubMed)
(36) The evaluation of anxiety and depression status in spouses of sexually active reproductive women withfibromyalgia by Yener M1, Askin A1, Soyupek F1, Akpinar A2, Demirdas A2, Sonmez S3, Soyupek S3.(PubMed)
(37) Quality of life, depression, and sexual dysfunction in spouses of female patients with fibromyalgia by Tutoglu A1, Boyaci A, Koca I, Celen E, Korkmaz N.(PubMed)
(38)  Psychological control is a key modulator of fibromyalgia symptoms and comorbidities. by Malin K1, Littlejohn GO.(PubMed)
(39) Stress perception and depressive symptoms: functionality and impact on the quality of life of women withfibromyalgia.[Article in English, Portuguese] by Homann D1, Stefanello JM, Góes SM, Breda CA, Paiva Edos S, Leite N.(PubMed)
(40) The evaluation of anxiety and depression status in spouses of sexually active reproductive women withfibromyalgia by Yener M1, Askin A1, Soyupek F1, Akpinar A2, Demirdas A2, Sonmez S3, Soyupek S3.(PubMed)
(41) Gender differences in pain severity, disability, depression, and widespread pressure pain sensitivity in patients with fibromyalgia syndrome without comorbid conditions by Castro-Sánchez AM1, Matarán-Peñarrocha GA, López-Rodríguez MM, Lara-Palomo IC, Arendt-Nielsen L, Fernández-de-las-Peñas C.(PubMed)
(42) Short-term effects of a manual therapy protocol on pain, physical function, quality of sleep, depressive symptoms, and pressure sensitivity in women and men with fibromyalgia syndrome: a randomized controlled trial by Castro-Sánchez AM1, Aguilar-Ferrándiz ME, Matarán-Peñarr, the ocha GA, Sánchez-Joya Mdel M, Arroyo-Morales M, Fernández-de-las-Peñas C.(PubMed). 
(43) Disability in Fibromyalgia Associates with Symptom Severity and Occupation Characteristics by Fitzcharles MA1, Ste-Marie PA1, Rampakakis E1, Sampalis JS1, Shir Y1.(PubMed)
(44) Stress perception and depressive symptoms: functionality and impact on the quality of life of women withfibromyalgia.[Article in English, Portuguese] by Homann D1, Stefanello JM, Góes SM, Breda CA, Paiva Edos S, Leite N.(PubMed)
(45) Relationship between the body image and level of pain, functional status, severity of depression, and quality of life in patients with fibromyalgia syndrome by Akkaya N1, Akkaya S, Atalay NS, Balci CS, Sahin F.(PubMed)
(46) Measuring health status in Israeli patients with fibromyalgia syndrome and widespread pain and healthy individuals: utility of the short form 36-item health survey (SF-36) by Neumann L1, Berzak A, Buskila D.(PubMed)
(47) Assessment of the relationship between postural stability and sleep quality in patients with fibromyalgia by Akkaya N1, Akkaya S, Atalay NS, Acar M, Catalbas N, Sahin F.(PubMed)
(48) Postural control deficits in people with fibromyalgia: a pilot study by Jones KD1, King LA, Mist SD, Bennett RM, Horak FB.(PubMed)
(49) Fibromyalgia is associated with impaired balance and falls by Jones KD1, Horak FB, Winters-Stone K, Irvine JM, Bennett RM.(PubMed)
(50) Postural control deficits in people with fibromyalgia: a pilot study by Jones KD1, King LA, Mist SD, Bennett RM, Horak FB.(PubMed)