Most Common Disease of50plus: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs)- Gout - The Top immune enhancers - Omega 3 fatty acids

Kyle J. Norton (Scholar and Master of Nutrients, all right reserved)Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
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Musculoskeletal disorders (MSDs) are medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. According to a community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home, musculoskeletal pain was reported by 57% of those interviewed(*).

Types of Musculo-Skeletal disorders in elder

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia

                                          Gout

Gout mostly effected one joint is an acute and recurrent condition of arthritis as a result of uric acid building up in blood, inducing joint inflammation.

The Top immune enhancers

Enhancing immunity has shown to reduced risk of inflammatory diseases(218). The University of Calgary study insisted "Uric acid crystals [monosodium urate (MSU)] have emerged as an important factor for both gouty arthritis and immune regulation. This simple crystalline structure appears to activate innate host defense mechanisms in multiple ways and triggers robust inflammation and immune activation"(219)


1. Omega 3 fatty acids
Omega-3 fatty acids, phytochemincals in the class of Lipids, found abundantly in dark-green leafy vegetables, grains, legumes, nuts, etc. play an impotant role in reduced risk of weaken immunity inducing inflammatory diseases, including gout(220). Dr. Simopoulos AP said, "omega-3 polyunsaturated fatty acids (PUFA) which possess the most potent immunomodulatory activities," and "Animal experiments and clinical intervention studies indicate that omega-3 fatty acids have anti-inflammatory properties and, therefore, might be useful in the management of inflammatory and autoimmune diseases."(221).

Omega 3 fatty acid for prevention of hyperlipidemia(223) may also be effective in reduced metabolic syndrome including hypertension, hyperuricemia, hyperinsulinemia......., according to the St. Thomas' Hospital, (222).

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References

(218) Immunity, inflammation, and cancer by Grivennikov SI1, Greten FR, Karin M.(PubMed)
(219) Monosodium urate crystals in inflammation and immunity by Shi Y1, Mucsi AD, Ng G.(PubMed)

(220) Omega 3 polyunsaturated fatty acids, inflammation and immunity by Calder PC1.(PubMed)

(221) Omega-3 fatty acids in inflammation and autoimmune diseases by Simopoulos AP1.(PubMed)

(222) Drug treatment of combined hyperlipidemia by Wierzbicki AS1, Mikhailidis DP, Wray R.(PubMed)