Thursday, 21 November 2013

Phytochemicals and Hashimoto's thyroiditis

Hashimoto's thyroiditis or chronic lymphocytic thyroiditis is defined as a condition of inflammation of the thyroid gland as a result of an autoimmune disease of that can lead to hypothyriodism due to weakened thyroid function.


Foods to prevent and treat Hashimoto's thyroiditis 
1.  Brazil Nuts and Sunflower Seeds

In the study to investigate [Selenium and thyroidal function; the role of immunoassays], showed that that dietary intake of about 300 micro g of selenium daily may have a toxic effect on growth hormone and insulin like growth factor-1 metabolism, as well as in the synthesis of thyroid hormones. Main adverse effects may be anorexia, diarrhea, depression, hemorrhage, liver and kidney necrosis, blindness, ataxia and respiratory disturbances. Dermatitis and CNS deficiency have also been described. It is concluded that selenium plays an important role in regulating thyroid function, as well as in the homeostasis of thyroid hormones through the action of selenoproteins, in which it incorporates as selenocystein(1). Others suggested that a different pattern of response to Se supplementation in HT relative to baseline TPOab titers, and this, if confirmed, could be used to identify which patients would benefit most from treatment. An improvement in thyroid function and morphology should be demonstrated before Se routine supplementation can be recommended in the treatment of HT(2).

2.  Sea buckthorn 
Sea buckthorn (Hippophae rhamnoides L.) constitutes thorny nitrogen fixing deciduous shrub. Sea buckthorn(SBT) is primarily valued for its very rich vitamins A, B(1), B(12), C, E, K, and P; flavonoids, lycopene, carotenoids, and phytosterols. and therapeutically important since it is rich with potent antioxidants. Scientifically evaluated pharmacological actions of SBT are like inflammation inhibited by reduced permeability, loss of follicular aggregation of lymphocytes from the inflamed synovium and suppress lymphocyte proliferation(3).

3.  Etc.

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Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/17160166
(2) http://www.ncbi.nlm.nih.gov/pubmed/20883174
(3) http://www.ncbi.nlm.nih.gov/pubmed/22530142

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