Friday, 10 January 2020

Green Bean, the Anti-inflammatory Veggie

By Kyle J. Norton

Inflammation is a natural defense of the immune system that protects the body against the insult from the foreign invasion.

Acute inflammation occurs quickly or within the hours and lasts a few days or weeks and the damaged tissues are healed themselves after all pathogens are killed off.

However, if the immune system can not completely eradicate all invaders in the acute phase of infection, it will compromise, leading to chronic low-grade inflammation, a major cause of cardiovascular disease, arthritis, and diabetes.

Chronic inflammation is a low-grade inflammation caused by the inability of the immune system to eliminate the invasive pathogens that occurred in the acute phase of infection.

Any inflammation that lasts more than 8 weeks is considered chronic inflammation.

Believe it or not, worldwide, 3 of 5 death are results from chronic inflammatory diseases like stroke, chronic respiratory diseases, heart disorders, cancer, obesity, and diabetes.

In the US, chronic inflammatory diseases affect more than 50 million Americans each year.

Anti-inflammation is a process that inhibits the pro-inflammatory cytokines without affecting the immune system activity against pathogens.

Diseases associated with low-grade inflammation include diabetes and cardiovascular.

Conventionally, Nonsteroidal anti-inflammatory drugs (NSAIDs) are the most common medical drugs such as aspirin. ibuprofen in reducing inflammation associated with pain-relieving.

Dr. Roma Pahwa in the classification of chronic inflammation wrote, "Chronic inflammation is also referred to as slow, long-term inflammation lasting for prolonged periods of several months to years. Generally, the extent and effects of chronic inflammation vary with the cause of the injury and the ability of the body to repair and overcome the damage".

And, "(The causes of chronic inflammation are) Failure of eliminating the agent causing acute inflammation, ..., Exposure to a low level of a particular irritant or foreign materials,...An autoimmune disorder,... Recurrent episodes of acute inflammation,... Inflammatory and biochemical inducers"

Green bean is a genus of Phaseolus Sensu Stricto, containing 55 difference species, belong to the family Fabaceae and native to the New World tropics and grown in Europe for its attractive flowers and fleshy immature pods. It can be classified into two major groups, bush beans, and pole beans.

On finding a potent veggie for the treatment of diseases associated with inflammation, researchers examined the effects of common beans hulls phenolic compounds (phenolic acids, flavonoids, and anthocyanins) and non-digestible fermentable components (short-chain fatty acid precursors) anti-inflammatory activities.

According to the tested analysis of extracted with two solvents, aqueous (70%) acetone and water from the common beans, including green beans, researchers found that
* Aqueous acetone (70%) extracted compared to other extracts showed over twice the amount of total phenolics from hulls in the exhibition of significantly higher antioxidant.

* Enzyme cyclooxygenases, COX-1 and COX-2 expression induced by proinflammatory cytokines at the site of inflammation were significantly inhibited by aqueous acetone compared to water extract.

* Bean hull water extracts expressed of oxidative enzyme lipoxygenase associated with inflammation also reduced.

Moreover, the anti-inflammatory activity of bean hulls was totally dependent on their phenolic content affected by the cultivar and extracting solvent antioxidant activity.

Taken altogether, green beans hulls may be used as an adjunct therapy for the prevention of inflammation, pending to the confirmation of larger sample size and multicenter human study.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

(1) Antioxidant and anti-inflammatory activities of bean ( Phaseolus vulgaris L.) hulls by Oomah BD1, Corbé A, Balasubramanian P. (PubMed)
(2) Chronic Inflammation by Roma Pahwa; Ishwarlal Jialal. (NCBI)

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