Wednesday, 29 January 2020

Broccli Processes Anti Nasopharyngeal Cancer Activity

By Kyle J. Norton

Cancers are a class of chronic and medical conditions characterized by cells growth irregularly and disorderly in the tissue of a specific organ.

Most cases of cancer start in the cell on the surface of the inner lining of organ tissue caused by the alternation of the cell DNA.

According to the National Cancer Institute, approximately 38.4% of men and women will be diagnosed with cancer at some point during their lifetimes, based on the 2013–2015 data.

In 2017, about15,270 children and adolescents ages 0 to 19 were diagnosed with cancer. Cancer in the same year also causes the death 1,790 of children and adolescents Americans.
The nasopharynx is the upper part of the pharynx, connecting with the nasal cavity above the soft palate that allows a person to breathe through the nose.

Nasopharyngeal cancer is a medical condition characterized by cells growth irregularly and disorderly in the tissues of the nasopharynx.

Most cases of nasopharyngeal cancer start in the cells on the surface of the inner lining of the nasopharynx.

According to the statistics provided by the American cancer society, nasopharyngeal cancer (NPC) is quite rare in the United States). The risk of cancer is less than one case for every 100,000 people.

Epidemiologically, some patients at this stage may also experience symptoms of frequent ear infections, hearing loss and headaches.

The exact causes of nasopharyngeal cancer are unknown. Gender, family history, ethnicity, where you live, poor diet, infected by the Epstein-Barr virus are some of the prevalent factors of nasopharyngeal cancer.
On finding a potential plant that processes anti-cancer activity researchers compared the effects investigate the role of miRNAs from broccoli in human nasopharyngeal cancer (NPC).

Where microRNAs (miRNAs), a small non-coding RNA molecule found in plants, animals and some viruses have been documented as having an important role in the development of cancer.

According to the analysis of a total of 84 conserved miRNAs and 184 putative novel miRNAs in broccoli by sequencing technology, the most abundant miR156a mimic inhibited the EMT of NPC cells in vitro.

The molecular genetics 3' UTR of Junctional adhesion molecule A (JAMA) associated with cancer cell migration and tight junctions was inhibited by the miR156a mimic on the tested EMT of NPC.

Collectively, researchers said, "These miRNA profiles of broccoli provide a fundamental basis for further research. Moreover, the discovery of miR156a may have clinical implications for the treatment of patients with NPC".

Taken altogether, broccoli which consists of microRNAs may be considered a functional food for the prevention and treatment of atherothrombotic diseases, pending to the confirmation of the larger sample size and multicenter human study.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

(1) miR156a Mimic Represses the Epithelial-Mesenchymal Transition of Human Nasopharyngeal Cancer Cells by Targeting Junctional Adhesion Molecule A by Tian Y1, Cai L1, Tian Y2, Tu Y1, Qiu H1, Xie G1, Huang D1, Zheng R1, Zhang W. (PubMed)

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