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Premenstrual syndrome effects over 70% to 90% of women before menopause in the US and less for women in Southeast Asia because of their difference in living style and social structure. It is defined as faulty function of the ovaries related to the women's menstrual cycle, it effects a women's physical and emotional state, and sometimes interferes with daily activities as a result of hormone fluctuation. The syndrome occurs one to two weeks before menstruation and then declines when the period starts. In this article, we will discuss How Traditional Chinese Medicine Helps to Treat PMS.
Traditional Chinese medicine used over 4000 thousand years in treating women reproductive system disorder believed Pre menstrual syndrome is caused by
Liver blood stagnation, is a milder form of impaired blood flow(2) in the abdominal region(1) including uterus causes of menstrual pain and cramps(1)(2) before the period. By releasing the blood stagnation, in the abdomen, certain herbs have shown to relieve symptoms of PMS, including migraine(2).
1. Angelica root
Angelica root is a queen for women reproductive system, used in traditional Chinese medicine in tonifying blood, promoting blood circulation(2), regulating menstruation(1), alleviating pain(2), and lubricating the bowels to relieve constipation(3), probably through its phytochemicalsè estrogenic(12)(13) and antiestrogenic(14) activities.
Angelica root also showed a protective effect against kidney injure(5)(6), radiation(7), cancers(8)(9)(15), osteoarthritis (OA)(10) and to improve immunity(4), dementia(16), female sexual dysfunction (FSD), menopausal symptoms(17), menopausal symptoms(18), etc. in modern studies.
2. Peony (Shao Yao)
Peony has been used in Chinese medicine in treating liver(20)(22)(27) blood stagnation(19) and induced blood flow by increasing the liver in blood formation(19) and promoting circulatory system for providing nutrients to our body need to nourish menstruation(20), relaxing spasm(22), relieving pain(22) and liver dysfunction(20) causes of tension of nervous system, such as anxiety(30).
Peony also showed a protective effect against influenza(20)(21), inflammatory diseases(24)(25), diabetes(26)(28)and triglycerides accumlation(26), cancers(21)(23), and to promote would healing(29), etc.. in modern studies.
3. Spatholobus spp (Ji Xue Teng)
Spathholobus spp is a blood tonic medicine, used in TCM to treat reproductive system disorders caused by blood stagnation(37) or blood deficiency(38), through increasing the production of blood(34) and moving the blood(37) for alleviating menstrual pain and cramps(39).
Spatholobus spp (Ji Xue Teng) also showed a protective effect against osteoarthritis (OA)(31), cancers(32)(33), fungal infection(34). inflammatory diseases(35), neurodegenerative disorders(36), etc.. in modern studies.
4. Ligusticum wallichi (Chuan Xiong)
Ligustium wallichi is also a herb for tonified blood circulation, including the abdominal region, used in Chinese medicine as reproductive system(42) enhancing herb through unblock blood vessels(43), regulate menstruation(42).
Ligusticum wallichi (Chuan Xiong) also showed a protective effect in vasorelaxant activity(43); improved the Left Ventricular Ejection Fractionof central nervous system(44), against dementia(45)(49), atherosclerosis(46, renal tubule damage(47), inflammation(48), myocardial ischemic reperfusion(50), lens opacification(51), etc.. in modern studies.
5. Red sage roots (Dan Shen)
Red sage root is a main Chinese medicine used for treatment of blood stagnation(52) in the abdominal region by improving the blood circulation in the body including abdominal region and breaking up stagnation(52).
Red sage roots (Dan Shen) also showed a protective effect of CNS(56) and against injuries involving the cranium and intracranial structures (craniocerebral injury), degeneration of spinal disks in the neck (cervical spondylosis) and brain dysfunctions related to disease of the blood vessels (cerebrovascular diseases)(53), atherosclerosis(54), convulsant activit(55), hepatitis B(57), chronic fatigue syndrome (CFS)(58), benign prostatic hyperplasia (BPH)(59), etc. in modern studies.
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(1) Ultrafine Angelica gigas powder normalizes ovarian hormone levels and has antiosteoporosis properties in ovariectomized rats: particle size effect by Choi KO1, Lee I, Paik SY, Kim DE, Lim JD, Kang WS, Ko S.(PubMed)
(2) Analgesic effect and mechanism of the three TCM-herbal drug-combination Tou Feng Yu pill on treatment of migraine by Li JC1, Shen XF, Meng XL, Zhang Y, Lai XR.(PubMed)
(3) Chinese Angelica Root(Eastern medicine export company)
(4) Immunomodulatory activity of polysaccharide isolated from Angelica sinensis by Yang T1, Jia M, Meng J, Wu H, Mei Q.(PubMed)
(5) [Therapeutic effect of Astragalus and Angelica on renal injury induced by ischemia/reperfusion in rats].[Article in Chinese] by Sheng MX1, Li JZ, Wang HY.(PubMed)
(6) [Adjustment effect of Radix Astragalus and Radix Angelicae sinensis on TNF-alpha and bFGF on renal injury induced by ischemia reperfusion in rabbit].
(13) Flavonoids possess neuroprotective effects on cultured pheochromocytoma PC12 cells: a comparison of different flavonoids in activating estrogenic effect and in preventing beta-amyloid-induced cell death by Zhu JT1, Choi RC, Chu GK, Cheung AW, Gao QT, Li J, Jiang ZY, Dong TT, Tsim KW.(PubMed)
(14) Isoflavones: chemistry, analysis, functions and effects on health and cancer by Ko KP.(PubMed)
(20) Characterization of the anti-influenza activity of the Chinese herbal plant Paeonia lactiflora by Ho JY1, Chang HW2, Lin CF3, Liu CJ4, Hsieh CF5, Horng JT6(PubMed)
(21) Anti-viral activity of water extract of Paeonia lactiflora pallas against human respiratory syncytial virus in human respiratory tract cell lines by Lin TJ1, Wang KC, Lin CC, Chiang LC, Chang JS.(PubMed)
(23) Paeoniflorin inhibited the tumor invasion and metastasis in human hepatocellular carcinoma cells by Lu JT, He W, Song SS, Wei W.(PubMed)
(24) Paeoniflorin abrogates DSS-induced colitis via a TLR4-dependent pathway by Zhang J1, Dou W, Zhang E, Sun A, Ding L, Wei X, Chou G, Mani S, Wang Z.(PubMed)
(25) The anti-inflammatory effect of paeoniflorin on cerebral infarction induced by ischemia-reperfusion injury in Sprague-Dawley rats by Tang NY1, Liu CH, Hsieh CT, Hsieh CL.(PubMed)
(26) Triglyceride accumulation: inhibitory effects of tangzhiqing formula by An Y1, Liu X, Qian Q, Zhang D, Li Y, Gao X, Zhang Y, Wang T.(PubMed)
(27) Paeoniflorin regulates macrophage activation in dimethylnitrosamine-induced liver fibrosis in rats by Chen X1, Liu C, Lu Y, Yang Z, Lv Z, Xu Q, Pan Q, Lu L.(PubMed)
(28) [Effects of total glucosides of paeony on enhancing insulin sensitivity and antagonizing nonalcoholic fatty liver in rats].[Article in Chinese] by Zheng LY1, Pan JQ, Lv JH.(PubMed)
(29) Wound-healing plants from TCM: in vitro investigations on selected TCM plants and their influence on human dermal fibroblasts and keratinocytes by Wang R1, Lechtenberg M, Sendker J, Petereit F, Deters A, Hensel A.(PubMed)
(30) Anxiolytic-like effect of paeonol in mice by Mi XJ1, Chen SW, Wang WJ, Wang R, Zhang YJ, Li WJ, Li YL.(PubMed)
(31) Water extract of Spatholobus suberectus inhibits osteoclast differentiation and bone resorption by