Monday, 8 December 2014

Premenstrual Syndrome(PMS) caused by Liver blood stagnation in Chinese Herbs Perspective

 By Kyle J. Norton 
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Premenstrual syndrome effects over 70% to 90% of women before menopause in the US and less for women in Southeast Asia because of their difference in living style and social structure. It is defined as faulty function of the ovaries related to the women's menstrual cycle, it effects a women's physical and emotional state, and sometimes interferes with daily activities as a result of hormone fluctuation. The syndrome occurs one to two weeks before menstruation and then declines when the period starts. In this article, we will discuss How Traditional Chinese Medicine Helps to Treat PMS.
Traditional Chinese medicine used over 4000 thousand years in treating women reproductive system disorder believed Pre menstrual syndrome is caused by

Liver blood stagnation, is a milder form of impaired blood flow(2) in the abdominal region(1) including uterus causes of  menstrual pain and cramps(1)(2) before the period. By releasing the blood stagnation,  in the abdomen, certain herbs have shown to relieve symptoms of PMS, including migraine(2).
1. Angelica root
 Angelica root is a queen for women reproductive system, used in traditional Chinese medicine in tonifying blood, promoting blood circulation(2), regulating menstruation(1), alleviating pain(2), and lubricating the bowels to relieve constipation(3), probably through its phytochemicalsè estrogenic(12)(13) and antiestrogenic(14) activities.
Angelica root also showed a protective effect against kidney injure(5)(6), radiation(7), cancers(8)(9)(15), osteoarthritis (OA)(10) and  to improve immunity(4), dementia(16), female sexual dysfunction (FSD), menopausal symptoms(17), menopausal symptoms(18), etc. in modern studies.
2. Peony (Shao Yao)
 Peony has been used in Chinese medicine in treating liver(20)(22)(27) blood stagnation(19) and induced blood flow by increasing the liver in blood formation(19) and promoting circulatory system for providing nutrients to our body need to
nourish menstruation(20), relaxing spasm(22), relieving pain(22) and  liver dysfunction(20) causes of tension of nervous system, such as anxiety(30).

Peony also showed a protective effect against influenza(20)(21), inflammatory diseases(24)(25), diabetes(26)(28)and triglycerides accumlation(26), cancers(21)(23), and to promote would healing(29), etc.. in modern studies.

3. Spatholobus spp (Ji Xue Teng)
Spathholobus spp is a blood tonic medicine, used in TCM to treat reproductive system disorders caused by blood stagnation(37) or blood deficiency(38), through increasing the production of blood(34) and moving the blood(37) for alleviating menstrual pain and cramps(39).

Spatholobus spp (Ji Xue Teng) also showed a protective effect against osteoarthritis (OA)(31), cancers(32)(33), fungal infection(34). inflammatory diseases(35), neurodegenerative disorders(36), etc.. in modern studies.

4. Ligusticum wallichi (Chuan Xiong)
Ligustium wallichi is also a herb for tonified blood circulation, including the abdominal region, used in Chinese medicine as reproductive system(42) enhancing herb through
unblock blood vessels(43), regulate menstruation(42).

Ligusticum wallichi (Chuan Xiong) also showed a protective effect in vasorelaxant activity(43); improved the Left Ventricular Ejection Fractionof central nervous system(44), against dementia(45)(49), atherosclerosis(46, renal tubule damage(47), inflammation(48), myocardial ischemic reperfusion(50), lens opacification(51), etc.. in modern studies.

5. Red sage roots (Dan Shen)

Red sage root is a main Chinese medicine used for treatment of blood stagnation(52) in the abdominal region by improving the blood circulation in the body including abdominal region and breaking up stagnation(52).

Red sage roots (Dan Shen) also showed a protective effect of CNS(56) and against injuries involving the cranium and intracranial structures (craniocerebral injury), degeneration of spinal disks in the neck (cervical spondylosis) and brain dysfunctions related to disease of the blood vessels (cerebrovascular diseases)(53), atherosclerosis(54), convulsant activit(55), hepatitis B(57), chronic fatigue syndrome (CFS)(58), benign prostatic hyperplasia (BPH)(59), etc. in modern studies.

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(1) Ultrafine Angelica gigas powder normalizes ovarian hormone levels and has antiosteoporosis properties in ovariectomized rats: particle size effect by Choi KO1, Lee I, Paik SY, Kim DE, Lim JD, Kang WS, Ko S.(PubMed)
(2) Analgesic effect and mechanism of the three TCM-herbal drug-combination Tou Feng Yu pill on treatment of migraine by Li JC1, Shen XF, Meng XL, Zhang Y, Lai XR.(PubMed)
(3) Chinese Angelica Root(Eastern medicine export company)
(4) Immunomodulatory activity of polysaccharide isolated from Angelica sinensis by Yang T1, Jia M, Meng J, Wu H, Mei Q.(PubMed)
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(6) [Adjustment effect of Radix Astragalus and Radix Angelicae sinensis on TNF-alpha and bFGF on renal injury induced by ischemia reperfusion in rabbit].
[Article in Chinese] by Xu XY1, Li LH, Wu LS, Zhao CL, Lin HY.(PubMed)
(7) Water-soluble polysaccharides from Angelica sinensis (Oliv.) Diels: Preparation, characterization and bioactivity by Sun Y1, Tang J, Gu X, Li D.(PubMed
(8) [Structural analysis and anti-tumor activity in vivo of polysaccharide APS-2a from Angelica sinensis].
[Article in Chinese] by Cao W1, Li XQ, Hou Y, Fan HT, Zhang XN, Mei QB.(PubMed)
(9) Experimental study of anti-tumor effects of polysaccharides from Angelica sinensis by Shang P1, Qian AR, Yang TH, Jia M, Mei QB, Cho CH, Zhao WM, Chen ZN.(PubMed
(10) Effect of Angelica sinensis Polysaccharides on Osteoarthritis In Vivo and In Vitro: A Possible Mechanism to Promote Proteoglycans Synthesis by Qin J1, Liu YS, Liu J, Li J, Tan Y, Li XJ, Magdalou J, Mei QB, Wang H, Chen LB.(PubMed
(11) Angelica Sinensis polysaccharides stimulated UDP-sugar synthase genes through promoting gene expression of IGF-1 and IGF1R in chondrocytes: promoting anti-osteoarthritic activity by Wen Y1, Li J2, Tan Y1, Qin J1, Xie X2, Wang L1, Mei Q3, Wang H4, Magdalou J5, Chen L6.(PubMed
(12)Synergistic Action of Flavonoids, Baicalein, and Daidzein in Estrogenic and Neuroprotective Effects: A Development of Potential Health Products and Therapeutic Drugs against Alzheimer's Disease by Choi RC1, Zhu JT, Yung AW, Lee PS, Xu SL, Guo AJ, Zhu KY, Dong TT, Tsim KW.(PubMed)
(13) Flavonoids possess neuroprotective effects on cultured pheochromocytoma PC12 cells: a comparison of different flavonoids in activating estrogenic effect and in preventing beta-amyloid-induced cell death by Zhu JT1, Choi RC, Chu GK, Cheung AW, Gao QT, Li J, Jiang ZY, Dong TT, Tsim KW.(PubMed)
(14) Isoflavones: chemistry, analysis, functions and effects on health and cancer by Ko KP.(PubMed)
(15) Modulation of HER2 expression by ferulic acid on human breast cancer MCF7 cells by Chang CJ1, Chiu JH, Tseng LM, Chang CH, Chien TM, Wu CW, Lui WY.(PubMed)
(16) Traditional chinese medicine for senile dementia by Lin Z1, Gu J, Xiu J, Mi T, Dong J, Tiwari JK.(PubMed)
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(20) Characterization of the anti-influenza activity of the Chinese herbal plant Paeonia lactiflora by Ho JY1, Chang HW2, Lin CF3, Liu CJ4, Hsieh CF5, Horng JT6(PubMed)
(21) Anti-viral activity of water extract of Paeonia lactiflora pallas against human respiratory syncytial virus in human respiratory tract cell lines by Lin TJ1, Wang KC, Lin CC, Chiang LC, Chang JS.(PubMed)
(23) Paeoniflorin inhibited the tumor invasion and metastasis in human hepatocellular carcinoma cells by Lu JT, He W, Song SS, Wei W.(PubMed)
(24) Paeoniflorin abrogates DSS-induced colitis via a TLR4-dependent pathway by Zhang J1, Dou W, Zhang E, Sun A, Ding L, Wei X, Chou G, Mani S, Wang Z.(PubMed)
(25) The anti-inflammatory effect of paeoniflorin on cerebral infarction induced by ischemia-reperfusion injury in Sprague-Dawley rats by Tang NY1, Liu CH, Hsieh CT, Hsieh CL.(PubMed)
(26) Triglyceride accumulation: inhibitory effects of tangzhiqing formula by An Y1, Liu X, Qian Q, Zhang D, Li Y, Gao X, Zhang Y, Wang T.(PubMed)
(27) Paeoniflorin regulates macrophage activation in dimethylnitrosamine-induced liver fibrosis in rats by Chen X1, Liu C, Lu Y, Yang Z, Lv Z, Xu Q, Pan Q, Lu L.(PubMed)
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(29) Wound-healing plants from TCM: in vitro investigations on selected TCM plants and their influence on human dermal fibroblasts and keratinocytes by Wang R1, Lechtenberg M, Sendker J, Petereit F, Deters A, Hensel A.(PubMed)
(30) Anxiolytic-like effect of paeonol in mice by Mi XJ1, Chen SW, Wang WJ, Wang R, Zhang YJ, Li WJ, Li YL.(PubMed)
(31) Water extract of Spatholobus suberectus inhibits osteoclast differentiation and bone resorption by
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(36) Neuroprotective effects of formononetin against NMDA-induced apoptosis in cortical neurons by Tian Z1, Liu SB, Wang YC, Li XQ, Zheng LH, Zhao MG.(PubMed
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(39) Backache and Chinese herbs(traditional Chinese medicine)
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(41) [Clinical and experimental study of Ligusticum wallichii and aspirin in the treatment of transient ischemic attack].[Article in Chinese] by Chen DR.(PubMed)
(42) Ligusticum wallichi (Chuan Xiong)(TCMWiki)
(43)Endothelium-independent vasorelaxation by Ligusticum wallichii in isolated rat aorta: comparison of a butanolic fraction and tetramethylpyrazine, the main active component of Ligusticum wallichii by Kim EY1, Kim JH, Rhyu MR.(PubMed)
(44) Ligusticum wallichii Extract Inhibited the Expression of IL-1β after AMI in Rat by Zhuo Yuan, 1 Junping Zhang, 1 ,* and Cui Yang(PubMed)
(45) Neuroprotective effects of tetramethylpyrazine against dopaminergic neuron injury in a rat model of Parkinson's disease induced by MPTP by Lu C1, Zhang J2, Shi X3, Miao S1, Bi L1, Zhang S4, Yang Q1, Zhou X1, Zhang M1, Xie Y1, Miao Q1, Wang S1.(PubMed)
(46) Study on anti-atherosclerotic effect of Suxiao Jiuxin Pill and its mechanism by Guo QX, Zhang J, Li YQ, Zhang GF.(PubMed)
(47) Ligustrazine attenuates elevated levels of indoxyl sulfate, kidney injury molecule-1 and clusterin in rats exposed to cadmium by Lan Z1, Bi KS1, Chen XH2.(PubMed)
(48) Prevention of inflammation-mediated neurotoxicity by butylidenephthalide and its role in microglial activation by Nam KN1, Kim KP, Cho KH, Jung WS, Park JM, Cho SY, Park SK, Park TH, Kim YS, Lee EH.(PubMed)
(49) Polyphenols and neuroprotection against ischemia and neurodegeneration by Lin B.(PubMed)
(50) Effect of Ligusticum wallichii aqueous extract on oxidative injury and immunity activity in myocardial ischemic reperfusion rats by Zengyong Q1, Jiangwei M, Huajin L.(PubMed)
(51) Protective effects and mechanism of tetramethylpyrazine against lens opacification induced by sodium selenite in rats by Li N1, Zhu Y, Deng X, Gao Y, Zhu Y, He M.(PubMed)
(52) Selection of component drug in activating blood flow and removing blood stasis of Chinese herbal medicinal formula for dairy cow mastitis by hemorheological method by Lu Y1, Hu YL, Kong XF, Wang DY.(PubMed)
(53)The development of nao li shen and its clinical application by Lu SL1, Liu X, Wang JL, Ying Q, Hu SG, Hu PP, Zhu GP, Zhen HW, Bai YT, Wang Q.(PubMed)
craniocerebral injury), degeneration of spinal disks in the neck (cervical spondylosis) and brain dysfunctions related to disease of the blood vessels (cerebrovascular diseases)
(54) Effects of huoxue injection on the adherence of human monocytes to endothelial cells and expression of vascular cell adhesion molecules].[Article in Chinese]by Zhu LQ1, Wang SR, Qin Y.(PubMed)
(55) Tanshinone IIA exhibits anticonvulsant activity in zebrafish and mouse seizure models by Buenafe OE1, Orellana-Paucar A, Maes J, Huang H, Ying X, De Borggraeve W, Crawford AD, Luyten W, Esguerra CV, de Witte P.(PubMed)
(56) Neuroprotective effects of tanshinones in transient focal cerebral ischemia in mice by Lam BY1, Lo AC, Sun X, Luo HW, Chung SK, Sucher NJ.(PubMed)
(57) [Study of xiaozhang recipe combined with lamivudine in treatment of 84 chronic viral hepatitis B patients with compensated liver cirrhosis][Article in Chinese]  by Zhou ZH1, Li M, Huang LY.(PubMed)
(58) [Effect of lixu jieyu recipe in treating 75 patients with chronic fatigue syndrome].[Article in Chinese]
(59) [Clinical observation on ziyin tongbi decoction in treating benign prostatic hyperplasia][Article in Chinese] by Guo J1, Song CS, Han Q.(PubMed)


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