Food Therapy: Cruciferous Vegetables - The Whole Food Medicine in Expression of Immunodulatory Effects

Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Whole food(herbal medicine) used as medical treatment,  linking health benefits in prevention, management and treatment of diseases has induced much interests in today renowned scientists.
But many researchers have raised question of herbal quality, as geographic differences, time of grown and harvest, etc. may affect their's potency. I do believe, these questions can only be answered by experience herbalists.

Intake of cruciferous vegetables regularly may improve immune function in lowering the toxic effects of environmental pollutants such as dioxin.
Aryl hydrocarbon receptor (AhR), a protein best known for its role in mediating toxicity, showed to reduce toxin effect through exhibited intestinal immune function, according to the The University of Texas Southwestern Medical Center at Dallas.

Cruciferous vegetables are the group of vegetables belonging to the family Brassicaceae, including cauliflower, cabbage, cress, bok choy, broccoli etc.

Phenethyl isothiocyanate, a chemical found in Cruciferous Vegetables, in normal BALB/c mice study, promoted immune responses in inhibition of murine leukemia WEHI-3 cells, through stimulating the immunomodulations.

Other phytochemicals, indole-3-carbinol and sulforaphane (SFN), found in the vegetables also addressed the immunodulatory effects against suppression of growth of murine WEHI-3 leukemia cells through immune promotion of increased the level of T cells and decreased the level of macrophages, a mobile white blood cell in responsible for detecting, engulfing and destroying pathogens and apoptotic cells.

In enzyme-linked immunosorbent assay, sulforaphane (SFN), inhibited T cell proliferation and the production of inflammatory cytokins in rheumatoid arthritis (RA) by enhancing the antiarthritic and immune regulatory effects.

Truly, Cruciferous Vegetable has no doubt processed  immunodulatory effects through the presence of  its phytochemicals in promotion of immune function.

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Sources
(1) You AhR what you eat: linking diet and immunity by Hooper LV1.(PubMed)
(2) Phenethyl isothiocyanate promotes immune responses in normal BALB/c mice, inhibits murine leukemia WEHI-3 cells, and stimulates immunomodulations in vivo by Tsou MF1, Tien N, Lu CC, Chiang JH, Yang JS, Lin JP, Fan MJ, Lu JJ, Yeh SP, Chung JG.(PubMed)
(3) In vitro suppression of growth of murine WEHI-3 leukemia cells and in vivo promotion of phagocytosis in a leukemia mice model by indole-3-carbinol by Lu HF1, Tung WL, Yang JS, Huang FM, Lee CS, Huang YP, Liao WY, Chen YL, Chung JG.(PubMed)
(4) Inhibition of synovial hyperplasia, rheumatoid T cell activation, and experimental arthritis in mice by sulforaphane, a naturally occurring isothiocyanate by Kong JS1, Yoo SA, Kim HS, Kim HA, Yea K, Ryu SH, Chung YJ, Cho CS, Kim WU.(PubMed)