Thursday, 21 November 2013

Testosterone Deficiency - The Symptoms

Testosterone is a male hormone, besides promoting libido it has other important functions such as maintaining muscle mass and form bone, regulating heart muscle and cholesterol. It also helps to improve the oxygen levels throughout the body as well as controlling blood glucose and strengthening the immune system. In this article, we will discuss symptoms of low levels of testosterone.

1. Decreased sexual function
As we mentioned in the last article, starting at age 40 levels of testosterone start to diminish, the levels of the by-product prolactin of testosterone of men increases, stimulating the production of the enzyme 5-alpha reductase that causes the conversion of testosterone to gihydro-testosterones DHT thus triggering low levels of testosterone resulting in sexual dysfunction.

2. Loss of bone density
The brain and bone are the important tissues that have the primary effect of testosterone is by way of aromatization to 17β estradiol. In the bones. 17β-estradiol accelerates maturation of cartilage into bone, leading to closure of the epiphyses (a rounded end of a long bone) and conclusion of growth.

3. Loss of muscle mass
As men start aging or damage of pituitary gland or extra estrogen build up in the body causing low levels of testosterone being produced resulting in loss of muscle mass. Testosterone effects can be classified as anabolic effects that include growth of muscle mass and strength, increased bone density and strength, and stimulation of height growth and bone maturation. Testosterone effects can also be classified by the age of usual occurrence.

4. Memory loss
Low levels of testosterone allows beta-amyloid, a toxic peptide to accumulate in certain regions of the brain causing memory loss.

5. Abdominal fat
Fat cells create aromatase enzymes that contribute to fat build up and low levels of testosterone that allows the forming of abdominal fat that produce more aromatase enzyme resulting in more formation of estrogen. It also causes insulin resistance by increasing fat around the stomach/waist area and fat mass.
There are more symptoms of low levels of testosterone such as timidity, feeling of weakness, passive attitude, etc.

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