Sunday 24 November 2013

Polymalagia Arthritis - The do’s and do not’s list

Polymalagia Arthritis Polymalagia Arthritis is defined as a condition a common inflammatory rheumatic disease which cause pain, stiffness and tenderness in large muscles, including muscles shoulders and pelvic girdleas a result of the presence of a synovitis in proximal joints and periarticular structures, causing musculoskeletal symptoms in PMR.
In conventional medicine, there is no known way to prevent Polymalagia Arthritis, although progression of the disease usually can be stopped or slowed by early, aggressive treatment. Since Polymalagia Arthritis is caused by inflammation pain, stiffness and tenderness in large muscles, including muscles shoulders and pelvic girdleas a result of the presence of a synovitis in proximal joints and periarticular structures. Diet with high in anti inflammatory and immunity enhancing foods, antioxidants and phytochemicals may provide protection and reduced risk of the disease.
E.1. The do’s and  do not’s list
1. Reduce intake of saturated and trans fat and increase intake of omega 3 fatty acids
 Although Limited studies have shown that certain dietary fatty acids (ie, oleic acid and alpha-linolenic acid) reduce biomarkers of inflammation. Most of the studies with fish oil supplementation have shown null effects, and conflicting results have been reported with saturated and trans fatty acids(26). Intake of high amount of saturated fat and trans fay can increase the production of inflammatory cytokines. Also There is reasonably strong evidence that omega-3 fatty acids may help people with rheumatoid arthritis. The results of over 13 double-blind, placebo-controlled studies involving a total of more than 500 people suggest that omega-3 fatty acids may improve symptoms of rheumatoid arthritis. One of the ways it appears to work is by decreasing the production of inflammatory chemicals(27).
2. Increase intake of increasing the ratio of (n-3) : (n-6) PUFA
Coinciding with this increase in the ratio of (n-6) : (n-3) PUFA are increases in chronic inflammatory diseases such as nonalcoholic fatty liver disease (NAFLD), cardiovascular disease, obesity, inflammatory bowel disease (IBD), rheumatoid arthritis, and Alzheimer’s disease (AD). By increasing the ratio of (n-3) : (n-6) PUFA in the Western diet, reductions may be achieved in the incidence of these chronic inflammatory diseases(28).
2. Increase intake of fruit and vegetable 
In a cross-sectional study of ≈1200 Puerto Rican adults aged 45-75 y, we assessed FV intake with a food-frequency questionnaire, Dr. Bhupathiraju SN, and Dr.Tucker KL. at the Tufts University, showed that FV variety, but not quantity, appears to be important in reducing inflammation. Although the results are suggestive, larger studies are needed to confirm a possible association with CHD risk score(29).
3. Avoid high glycemic index diets
Other studies suggested that the consumption of high glycemic index diets, which have low fiber content and are rich in trans fat cause the activation of the immune system, leading to excessive production of pro-inflammatory mediators and the reduction of the anti-inflammatory ones. Although the results are controversial, healthy dietary intakes with the reduction in fat intake (especially trans and saturated fat) and the increase in fruits, vegetables, and whole grain consumption seem to be associated with the improvement in subclinical inflammatory condition(30).
4. Reduced intake of pro inflammatory foods, such as sugar, dairy products, red meat and processed, meat, alcohol, artificial ingredients, refined products, etc.
5. Increase in take of anti inflammatory foods, such as fresh vegetables and fruits, seeds and sprouts whole grain, fish, turkey, chicken, legumes, etc.
6. Stop smoking
As smoking are associated with increased of Polymalagia Arthritis.
7. Moderate exercise
Moderate exercise enhances immune function in fighting against inflammation and increase the blood circulation to provide nutrients to the body’s organs need
8. Etc.
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Sources
(28) http://www.ncbi.nlm.nih.gov/pubmed/22570770
(29) http://www.ncbi.nlm.nih.gov/pubmed/22696854
(30) http://www.ncbi.nlm.nih.gov/pubmed/18820806

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