Monday, 25 November 2013

Pleural disease – Phytochemicals and Pleural plaques

The pleura is a thin tissue covered by a layer of cells (mesothelial cells) that surrounds the lungs and lines the inside of the chest wall.
C. Pleural plaques
Pleural plaques is a medical condition as a result of exposure to asbestos that lead to accumulated plagues within the pleural cavity(a). Many diseases such as pneumonia, breast cancer, and heart failure can affect the pleural space.,therefore, it is often a secondary effect of another disease process.
E. Preventions
4. Phytochemicals to prevent pleural plague
a. Epigallo-catechin-galleate (EGCG)
According to the study by the Harvard Medical School, Boston, EGCG abundantly in green tea, has great potential in ameliorating the development of obliterative airway disease(29).
b. Catechin polyphenols (GTPs)
Other study indicated that oral green tea catechin polyphenols (GTPs) attenuates IH-induced spatial learning deficits and mitigates IH-induced oxidative stress through multiple beneficial effects on oxidant pathways(30).
c. Curcumin (diferuloylmethane)
Curcumin (diferuloylmethane) is an orange-yellow component of turmeric (Curcuma longa), a spice often found in curry powder. According to the study by, curcumin has been shown in the last two decades to be a potent immunomodulatory agent that can modulate the activation of T cells, B cells, macrophages, neutrophils, natural killer cells, and dendritic cells. Curcumin can also downregulate the expression of various proinflammatory cytokines including TNF, IL-1, IL-2, IL-6, IL-8, IL-12, and chemokines, most likely through inactivation of the transcription factor NF-kappaB. Interestingly, however, curcumin at low doses can also enhance antibody responses(31).
d. Ursolic acid, betulin
In the study to investigate whether ursolic acid, betulin and 2 kinds of sulfur-containing compounds–NAC and MESNA–affect mucin release from airway goblet cells and compared the possible activities of these agents with the inhibitory action on mucin release by PLL and the stimulatory action by ATP, showed that ursolic acid and betulin can stimulate mucin release by directly acting on airway mucin-secreting cells and suggest that these agents be further investigated for the possible use as mucoregulators in the treatment of chronic airway diseases(32).

Chinese Secrets To Fatty Liver And Obesity Reversal
Use The Revolutionary Findings To Achieve 
Optimal Health And Loose Weight

Back to General health

Back to Kyle J. Norton Home page

No comments:

Post a Comment