Friday, 22 November 2013

Phytochemicals and Hay fever

Hay fever is also known as allergic rhinitis, is a collections of many signs and symptoms similar to a cold with sneezing, watery, as a result of allergic effect, including dust, dander, insect venom, pollen, etc.

Types of food to prevent and treat Hay fever
1. Rosemary
In the study to to determine whether oral supplementation with rosmarinic acid (RA) is an effective intervention for patients with SAR. In addition, the anti-inflammatory mechanism of RA also estimated in the ear edema models, found that Reactive oxygen radical production detected as thiobarbituric acid reactive substance (TBARS), lipid peroxide (LPO) and 8-hydroxy-2'deoxyguanosine (8OH-dG), by double treatment of TPA was reduced by pretreatment with PE or RA. RA is an effective intervention for SAR that is mediated by inhibition of PMNL infiltration. This effect of RA is due to two independent mechanisms: inhibition of the inflammatory response and scavenging of ROS(1).

2. Fish oil (eicosapentaenoic acid)
 In the study of the investigation was to explore in a prospective study the associations between dietary intake of fatty acids, antioxidants and hay fever manifestation in adulthood, found that high intake of oleic acid was positively associated with hay fever [odds ratio (OR): 2.86, 95% confidence intervals (95% CI): 1.22-6.70], whereas high intake of eicosapentaenoic acid was inversely related to hay fever (OR: 0.45, 95% CI: 0.22-0.93). Furthermore, high beta-carotene intake increased the risk of hay fever (OR: 1.69, 95% CI: 1.09-2.63) while increasing intake of vitamin E was a protective factor (OR: 0.38, 95% CI: 0.17-0.85). In grouped analyses, the effects of beta-carotene and vitamin E were mainly observed among women and ex-/current-smokers; in these subgroups, linoleic acid increased the risk of hay fever(2).

3. Artichokes and milk thistle
Silymarin is a phytochemical in the class of Lignans (phytoestrogens), found abundantly in artichokes, milk thistle.  In the study to investigate Effect of silymarin in the treatment of allergic rhinitis, showed that Sixty patients completed the trial. Based on the Sino-Nasal Outcome Test 20 (SNOT-20), a significant improvement in clinical symptom severity was observed in both groups (9.23 ± 5.14 vs 2.20 ± 2.69; P < .001), which was statistically significantly higher in the study group (P < .001). Posttreatment percentage of nasal eosinophils and cytokine levels showed no significant difference (P > .05). Rise in serum IgE level was seen after treatment with silymarin (P = .003)(3).

4. Orange juice
In the study ofEffect of vitamin C on histamine bronchial responsiveness of patients with allergic rhinitis, showed that the effect of acute oral administration of 2 g vitamin C on bronchial responsiveness to inhaled histamine in 16 patients with allergic rhinitis was compared with placebo on two consecutive days in a double-blind, crossover design. The PC15FEV1 was significantly increased one hour after treatment with vitamin C but not after placebo(4).

5. Etc.

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Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/15630183
(2) http://www.ncbi.nlm.nih.gov/pubmed/14616103
(3) http://www.ncbi.nlm.nih.gov/pubmed/21952357
(4) http://www.ncbi.nlm.nih.gov/pubmed/2221490

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