Chronic obstructive pulmonary disease (COPD) is a progressive lung disease that makes it hard to breathe due to production of large amounts of mucus as a result of long term smoking, in general.
Types of food to prevent and treat Chronic obstructive pulmonary disease (COPD)
1. Neotropical blueberry and barley leaves
In the study of four flavone C-glycosides, isoorientin
(1), orientin (2), vitexin (3), and isovitexin (4), isolated from
the neotropical blueberry, using antioxidant activity-guided
fractionation, found that he four flavone C-glycosides exhibited
inhibitory activity against IL-8
production and MMP-1 expression, with compounds 1, 3, and 4 having the
most potent inhibitory activities in both assays at 100 μg/ml(1).
2. Turmeric
Cadmium is a toxic metal present in the environment and its inhalation can lead to pulmonary disease such as lung cancer and chronic obstructive pulmonary disease. These lung diseases are characterized by chronic
inflammation. In the study of Curcumin regulates airway epithelial cell
cytokine responses to the pollutant cadmium, researchers found that the
natural antioxidant curcumin could prevent both cadmium-induced IL-6
and IL-8 secretion by human airway epithelial cells. In conclusion,
curcumin could be used to prevent airway inflammation due to cadmium
inhalation(2).
3. Oats, sweet corn and rice
Oats, sweet corn and rice contain measurable amounts of melatonin. In
recent studies show that, α, β-unsaturated aldehyde acrolein in CS
induces the production of interleukin (IL)-8, which is known to be
related to bronchitis, rhinitis, pulmonary fibrosis, and asthma. In addition, lung and pulmonary
fibroblasts secrete IL-8, which has a chemotactic effect on leukocytes,
and which in turn, play a critical role in lung inflammation.
Acrolein-induced IL-8 production was accompanied by increased levels of
phosphorylation of Akt and extracellular signal-regulated kinases
(ERK1/2) in HPFs, and that melatonin suppressed IL-8 production in HPFs.
These results suggest that melatonin suppresses acrolein-induced IL-8
production via ERK1/2 and phosphatidylinositol 3-kinase (PI3K)/Akt
signal inhibition in HPFs(3).
4. Grape skin
In the study of the effects of grape skin in the pathogenesis and progression of chronic obstructive pulmonary disease (COPD), showed that alteration of the oxidant-antioxidant balance is important in the
pathogenesis of CS-induced ALI and suggests lung protective effects of
GSE treatment in the mouse(4).
5. Grape skin, seed and red wine
In the study to investigate the effect of dexamethasone versus
resveratrol on the
release of COPD-related inflammatory mediators (IL-6, IL-8, GM-CSF and
MCP-1) and matrix-metalloprotease-9 (MMP-9) from alveolar macrophages
exposed to gram-negative bacterial endotoxin (lipopolysaccharide, LPS),
found that resveratrol almost completely reduced the release of all
cytokines and
MMP-9 without significant differences between the cohorts. Our data
provide evidence for a corticosteroid resistance of alveolar
macrophage-dependent inflammatory responses induced by gram-negative
bacteria in COPD and thus question the utility of corticosteroids in
COPD therapy. Instead, resveratrol may prove an alternative(5).
6. Etc.
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Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed?term=isoorientin%20and%20COPD
(2) http://www.ncbi.nlm.nih.gov/pubmed/22142850
(3) http://www.ncbi.nlm.nih.gov/pubmed/21951103
(4) http://www.ncbi.nlm.nih.gov/pubmed/21804454
(5) http://www.ncbi.nlm.nih.gov/pubmed/21447053
Health Researcher and Article Writer. Expert in Health Benefits of Foods, Herbs, and Phytochemicals. Master in Mathematics & Nutrition and BA in World Literature and Literary criticism. All articles written by Kyle J. Norton are for information & education only.
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