Chronic Kidney disease is defined as a condition of the
progression loss of kidney function over period of many years. Stage of
chronic kidney disease according to the National Kidney Foundation's
Kidney Disease Outcomes Quality Initiative (KDOQ).
Stages Description GFR*
1. Signs of mild kidney disease but with normal or better GFR greater than 90%
2. Mild kidney disease with reduced GFR 60-89%
3. Moderate chronic renal insufficiency 30-59%
4. Severe chronic renal insufficiency 15-29%
5. End-stage renal failure less than 15%
*GFR is given in ml/min/1.73 m2
Types of foods to prevent and treat chronic kidney diseases
1. Honey
Individuals with chronic diseases are more susceptible to oxidative stress and damage because they have elevated levels of oxidants and/or reduced antioxidants.
In the study of Honey: a novel antioxidant, researchers found that
honey, administered alone or in combination with conventional therapy,
might be a novel antioxidant in the management of chronic diseases
commonly associated with oxidative stress. In view of the fact that the
majority of these data emanate from animal studies, there is an urgent
need to investigate this antioxidant effect of honey in human subjects
with chronic or degenerative diseases(1).
2. Kombu
Kombu is a popular seafood and medicinal plant
in China. In the study to exhibita new mechanism of fucoidan derivatives
on CKD rats, found that the mechanism of fucoidan derivatives on the
CKD rats had relationship
with their antioxidant activities, the samples which could enhance the
activity of antioxidant enzymes and reduce the LPO level could alleviate
the symptom of CKD(2).
3. Peanuts and bean
In the study to investigate whether oxidative stress or a relative deficit of l-arginine
plays a role in reducing cutaneous vasodilation in response to local
heating in chronic kidney disease (CKD) in Eight patients with stage 3-4 CKD and eight age- and sex-matched healthy
control (HC) subjects were instrumented with four microdialysis (MD)
fibers for the local delivery of 1) Ringers solution (R), 2) 20 mM
ascorbic acid (AA), 3) 10 mM l-arginine (l-Arg), and 4) 10 mM
N(G)-nitro-l-arginine methyl ester (l-NAME). Red blood cell (RBC) flux
was measured via laser Doppler flowmetry, showed that cutaneous microvascular function is impaired in stage 3-4 CKD and that
oxidative stress and a deficit of l-arginine play a role in this
impairment(3).
4. Flax seed or fish oil
In the study to elucidate whether PUFAs derived from plant or marine
oils could have beneficial effects on the progression of experimental chronic renal failure (CRF), indicated that fter 30 days, we observed lower levels of sCr in the groups supplemented
with PUFA when compared with the control group (FO: 0.92 ± 0.13; FXO:
1.06 ± 0.28; SO: 1.32 ± 0.47 mg/dL) and significantly slower variations
of sCr (ΔsCr) in the groups treated with PUFAs (FO = 0.35 ± 0.16;
FXO = 0.47 ± 0.31; OS = 0.72 ± 0.43; mg/dL, P = 0.041). Similarly, the
CLcr of both of the groups that received PUFAs was significantly slower
than the rats in the control group (FO: 0.45 ± 0.15; FXO: 0.60 ± 0.09;
SO: 0.28 ± 0.06 mL/min/day; P = 0.01). The rats that received PUFA
supplements also presented significantly less histological lesions
compared with the control group(4).
5. Etc.
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Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/22499188
(2) http://www.ncbi.nlm.nih.gov/pubmed/22210052
(3) http://www.ncbi.nlm.nih.gov/pubmed/21885796
(4) http://www.ncbi.nlm.nih.gov/pubmed/22752498
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