Monday, 18 November 2013

Phytochemicals and Allergy

Allergy is the over reaction of immune system to harmless substances after entering our body affecting 1 in every 3 people and is defined as the type I reactions or Immediate Hypersensitivity as a result of
over production of Immunoglobulin E (IgE), a class of allergic antibody by the immune system against harmless substance that lead to mediated release of histamine and other mediators from mast cells and basophils, resulting in allergic reaction, including mucus secretion, sneezing, itching, etc.

Types of foods tp prevent and treat Allergy
1. Yogurt
In the study to investigate the clinical effects of L-55-contained yogurt on symptoms and IgE production in the patients with Japanese cedar pollinosis, showed that the mean value of symptom score and symptom medication score were lower in L-55 yogurt group compared with placebo yogurt group during 5th week to 9th week from the first week of Japanese cedar pollination. Especially, in medicated subjects, total symptom score and throat symptom score were significantly lower in L-55 yogurt group compared with placebo yogurt group at 5th and 4th week from the first week of Japanese cedar pollination, respectively. Moreover, in medicated subjects, change ratio of serum total IgE was significantly lower in L-55 yogurt group compared with placebo yogurt group at 1st week from the first week of Japanese cedar pollination. Conclusion: Intake of L-55 during Japanese cedar pollinating season may be effective in alleviating the allergic symptoms related to Japanese cedar pollinosis. From these finding, it was suggested that L-55 is a possible candidate as a complementary medicine for Japanese cedar pollinosis(1). Other suggested that  intestinal bacteria such as the Bacteroides fragilis group significantly fluctuated during the pollen season in JCPsis individuals and intake of BB536 yogurt tended to suppress these fluctuations(1a).

2.  Tomato
In the study to identify the protein profile of the extract, to analyze the allergenic profile of individuals, and to determine cross-reactivity with other members of the Solanaceae family (tomato) after allergic effect with consumption of Goji, indicated that a positive skin prick test and specific immunoglobulin (Ig) E to Goji berry was detected in both cases. Serum samples recognized a 9-kDa band, probably related to lipid transfer proteins (LTPs). Cross-reactivity with tomato was analyzed by inhibition studies, which showed that the 9-kDa band was totally inhibited by the tomato extract(2).

3. Honey
According to the article of Seasonal Allergies? A Spoonful of Honey, posted in New York time on April 11-2010, Thomas Leo Ogren makes several good points about reducing the misery of people with seasonal allergies. Besides a variety of trees, there is a simpler way for allergy sufferers to find relief: local honey. This remedy (predating Claritin and its ilk) has long been recognized around the world(3)

4. Traditional Mediterranean diet
In the study to investigate a cross-sectional survey was performed in 690 children aged 7-18 years in rural Crete. Parents completed a questionnaire on their child's respiratory and allergic symptoms and a 58-item food frequency questionnaire. Adherence to a Mediterranean diet was measured using a scale with 12 dietary items. Children underwent skin prick tests with 10 common aeroallergens, showed that a beneficial effect of commonly consumed fruits, vegetables and nuts, and of a high adherence to a traditional Mediterranean diet during childhood on symptoms of asthma and rhinitis. Diet may explain the relative lack of allergic symptoms in this population(4).

5. Etc.

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Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/22705785
(1a) http://www.ncbi.nlm.nih.gov/pubmed/17893165 
(2) http://www.ncbi.nlm.nih.gov/pubmed/22312943
(3) http://www.nytimes.com/2010/04/12/opinion/l12allergy.html?_r=1
(4) http://www.ncbi.nlm.nih.gov/pubmed/17412780

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