Duodenal ulcers, a type of peptic ulcer is defined as a
condition of a localized tissue erosion in the lining the duodenum as a
result of bacteria Helicobacter pylori (H pylori) in most cases.
According to the study by Department of Research, University Hospital,
Basel, fasting gastrin and pepsinogen-I and -II concentrations were
significantly higher in H pylori positive compared with H pylori
negative subjects. Neither age nor sex affected basal gastrin and
pepsinogen concentrations in H pylori negative subjects. Fasting
gastrin, pepsinogen-I and -II concentrations in serum samples were
similar in H pylori positive persons with no symptoms and those with
duodenal ulcers suggesting that similar mechanisms are involved in
increasing plasma concentrations of these variables in both populations.
Hypergastrinaemia and hyperpepsinogenaemia are therefore probably
secondary to active H pylori.
F. Treatments
In Herbal medicine perspective
Herbal drugs have been proved to be very effective in treatment of hyperacidity, gastric and duodenal ulcer, include mucus: Lini
semen, Psylli semen, Foenugraeci semen, Althaeae radix/folium, Sinapis
albae semen; antiphlogistic volatile-oils: Chamomillae anthodium,
Millefolii herba, moreover Glycyrrhizae radix, Aloe gel, according
to the study of [Herbs and herbal preparations applied in the treatment
of gastric hyperacidity, gastric and duodenal ulcer in cigarette
smokers(34)].
2. Peloidin (Reloidinum).
Oral administration and electrophoresis of peloidin, extract from the
silt mud are beneficial in the lesions of the gastric and duodenal
mucosa. Plants infusions per os combined with the exposure to sinusoidal
modulated currents can be recommended in the disease aggravations,
scarry ulcerative deformities(35).
3. Spices, herbal xenobiotics
Despite a number of reports on the toxicity of herbs and spices, they
are generally accepted as safer alternatives to conventional therapy
against gastric ulcers. But excessive consumption of spices may favor
the pathogenesis of gastric and duodenal ulcer and some studies have
substantiated this common perception, according to the study of “Spices,
herbal xenobiotics and the stomach: friends or foes”(36).
4. Etc.
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Sources
(34) http://www.ncbi.nlm.nih.gov/pubmed/16521987
(35) http://www.ncbi.nlm.nih.gov/pubmed/1792722
(36) http://www.ncbi.nlm.nih.gov/pubmed/20533590
(37) http://www.ncbi.nlm.nih.gov/pubmed/23153037
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