Duodenal ulcers, a type of peptic ulcer is defined as a
condition of a localized tissue erosion in the lining the duodenum as a
result of bacteria Helicobacter pylori (H pylori) in most cases.
According to the study by Department of Research, University Hospital,
Basel, fasting gastrin and pepsinogen-I and -II concentrations were
significantly higher in H pylori positive compared with H pylori
negative subjects. Neither age nor sex affected basal gastrin and
pepsinogen concentrations in H pylori negative subjects. Fasting
gastrin, pepsinogen-I and -II concentrations in serum samples were
similar in H pylori positive persons with no symptoms and those with
duodenal ulcers suggesting that similar mechanisms are involved in
increasing plasma concentrations of these variables in both populations.
Hypergastrinaemia and hyperpepsinogenaemia are therefore probably
secondary to active H pylori.
The Diet
1. Honey
In the study to assess the antibacterial potential of various brands of
honey sold in Muscat area on some isolates of H. pylori and to determine
if there is any synergy between honey and amoxycillin or clarithromycin
used in the treatment of H. pylori gastritis and duodenal ulcer, found
that all honey samples produced growth inhibition zones with H. pylori
no at dilution of honey but had different zone sizes at 1:2-1:8
dilutions. Black Forest honey had the highest antibacterial activity
followed by Langnese honey. None of the honeys had a synergistic effect
with either clarithromycin or amoxycillin(
D.3. Phytochemicals to prevent Duodenal ulcers(18).
2. Probiotics
Helicobacter pylori infection, a highly prevalent pathogen, is a major
cause of chronic gastritis and peptic ulcer and a risk factor for
gastric malignancies. Animal studies demonstrated that probiotic
treatment is effective in reducing H. pylori-associated gastric
inflammation. Seven of 9 human studies showed an improvement of H.
pylori gastritis and decrease in H. pylori density after administration
of probiotics. The addition of probiotics to standard antibiotic
treatment improved H. pylori eradication rates (81% vs. 71%, with
combination treatment vs. H. pylori-eradication treatment alone;
chi(2)test: P=0.03). Probiotic treatment reduced H. pylori
therapy-associated side effects (incidence of side effects: 23% vs. 46%,
with combination therapy vs. H. pylori-eradication treatment alone;
chi(2)test: P=0.04)(19).
3. Oat
Oat has been chosen as a substrate for fermentation because it contains
100 times more of membrane lipids (surfactants) than any other food, has
a favorable amino acid pattern (rich in glutamine), and is rich in
water-soluble, fermentable-fiber beta-glucans. More than 1000 isolates
of human-specific lactobacilli have been studied. Some strains,
especially those of plantarum type, have proven effective in colonizing
the colonic mucosa, suppressing the potentially pathogenetic flora, and
may have other probiotic effects as well(20).
4. Onion
According to the study by The National Onion Association, Onions
functions as an antioxidant, deactivating molecules that are injurious
to cells in the body. Research studies have shown quercetin to promote
healing of stomach ulcers(21).
5. Etc.
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Sources
(18) http://heartburn.about.com/od/pepticulcers/a/ulcer_diet.htm
(19) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3074916/
(20) http://www.ncbi.nlm.nih.gov/pubmed/17311980
(21) http://www.ncbi.nlm.nih.gov/pubmed/8577022
Health Researcher and Article Writer. Expert in Health Benefits of Foods, Herbs, and Phytochemicals. Master in Mathematics & Nutrition and BA in World Literature and Literary criticism. All articles written by Kyle J. Norton are for information & education only.
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