Saturday, 2 November 2013

Chinese Herbs – Suan Zao Ren (Semen Zizyphi Spinosae)

Suan Zao Ren is also known as sour jujube seed. The sweet, sour, neutral and non toxic herb has been used in TCM to prevent abnormal sweating, treat anxiety, insomnia, excessive dream, weak memory, dizziness, etc., as it stops sweating, nourishes the Hear, calms the Mind, etc. by enhancing the functions of gallbladder, heart, liver and spleen channels.

Ingredients
1. Betulinic acid
2. Betulin
3. Ceanothic acid
4. Alphitolic acid
5. Iujuboside A,B
6. Ceanothic acid
7. Flavonoids
8. Alkaloids
9. Etc.

Health Benefits
1. Vascular actions of nitric oxide (NO) 
in the study to investigate the effect on eNOS gene expression of 15 Chinese herbs with potential effects on the vasculature, and identified Prunella vulgaris L. (PVL) (flowering spike) as a potent eNOS-upregulating agent, showed that an aqueous extract of PVL increased eNOS promoter activity, eNOS mRNA and protein expressions, as well as NO production in concentration- and time-dependent manners(1).
2. Hypnotic effect 
in the study to investigate the hypnotic effect of jujubosides, one of the major components (saponin) of Semen Ziziphi Spinosae, in both day and night period, found that the hypnotic effect of jujubosides on normal rats may be influenced by circadian rhythm and the serotonergic system may involve in the hypnotic effect of jujubosides. Jujubosides may be good source of lead compounds for novel hypnotics(2).
3. Sedative and hypnotic effects 
In the comparison the sedative and hypnotic effects of three kinds of compounds, flavonoids, saponins, and polysaccharides, showed that comparative analysis, saponins had a more effective sedative and hypnotic function than that of flavonoids, polysaccharides did not show a sedative and hypnotic effect(3).
4. Etc.

Side Effects
1. Do not use in case of diarrhea and anxiety as a result of chronic bronchitis
2. Do not use in case yeast or bacterial infection
3. Etc.
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Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/20503475
(2) http://www.ncbi.nlm.nih.gov/pubmed/20347951
(3) http://www.ncbi.nlm.nih.gov/pubmed/17479419

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