Holistic Health Articles and Research Related to Herbal Medicines, Foods and Phytochemicals : Chinese Herbs – He Huan Pi (Cortex Albizziae Julibrissin)

Saturday, 9 November 2013

Chinese Herbs – He Huan Pi (Cortex Albizziae Julibrissin)

He Huan Pi is also known as Albizzia bark. The sweet and neutral herb has been used in TCM as diuretic, tonic agent and to treat mood swing, insomnia, poor memory, relieve pain, etc., as it calms the Mind, resolves depression and stagnation, moves Blood, etc., by enhancing the functions of heart, liver and lung channels.

Ingredients

1. Acetic acid
2. Isovaleraldehyde
3. N-methylene-ethylenediamine
4. 4-penten-2-one
5. Isoamyl alcohol
6. Cis-3-hexen-1-ol
7. N-hexanol
8. Isoamyl acetate
9. 2-methylbutyl acetate
10. Isovaleroxyamine

11. Etc.

Health Benefits
1. Anti cancer
The indentfied of a a new triterpenoidal saponin (1: Julibroside J(21)) with a xylopyranosyl moiety located at its C-21 side chain of Albizia julibrissin hjave showed of inhibitory action against Bel-7402 cancer cell line at 10 microg/ml, according to “A cytotoxic saponin from Albizia julibrissin” by Zou K, Zhao YY, Zhang RY.(1) 2. Anti antitumors
The indentfied of a a new triterpenoidal saponin, julibroside J(28) (1), was isolated from the stem bark of Albizia julibrissin Durazz (Leguminosae) of Albizia julibrissin displayed significant antitumor activity in vitro against PC-3M-1E8, Bel-7402, and HeLa cancer cell lines at 10 microM assayed by SRB method, according to ‘An antitumor compound julibroside J28 from Albizia julibrissin” by Liang H, Tong WY, Zhao YY, Cui JR, Tu GZ.(2)
3. Acute leukemia
In the investigation of antitumor activity of Albizzia julibrissin Durazz (Leguminosae), used as a traditional oriental medicine, the mechanism underlying cytotoxic effect of its extract on human acute leukemia Jurkat T cells found that the cytotoxicity of HaBC18 toward Jurkat T cells is attributable to apoptosis mediated by mitochondria-dependent death-signaling pathway regulated by Bcl-xL, according to “Induction of apoptosis in human acute leukemia Jurkat T cells by Albizzia julibrissin extract is mediated via mitochondria-dependent caspase-3 activation” by Won HJ, Han CH, Kim YH, Kwon HJ, Kim BW, Choi JS, Kim KH.(3)

4. Sedative activity
The isolation of two flavonol glycosides, quercitrin (1) and isoquercitrin (2) of the flowers of Albizzia julibrissin, used as a sedative in oriental traditional medicine, both compounds 1 and 2 increased pentobarbital-induced sleeping time in dose-dependent manner in mice. These results support the use of the flowers of this plant as a sedative agent, according to “Sedative activity of two flavonol glycosides isolated from the flowers of Albizzia julibrissin Durazz” by Kang TH, Jeong SJ, Kim NY, Higuchi R, Kim YC.(4)
5. Arrhythmia
In the isolation of three pyridoxine derivatives from the fresh stem bark of Albizzia julibrissin DURAZZ., found that one of them, named julibrin II, was found to exhibit arrhythmic-inducing action. However, neither the others having the same aglycone nor some glycosides having the same sugar unit showed the action, according to “An arrhythmic-inducing glycoside from Albizzia julibrissin Durazz, IV” by Higuchi H, Kinjo J, Nohara T.(5)
6. Etc.

Side Effects

No side Effect is known