Gui Ban, Giu Jia or Gui Ban Jiao Is also known as Fresh Water Turtle Shell. The salty, sweet and neutral herb has been used in TCM to treat hot flashes with night sweating, chronic ache in loin and knees, spermatorrhea, chronic cough, palpitation, insomnia and forgetfulness, excesive bleeding during menses, etc., as it nourishes Yin, subdues Yang, tonifies the Kidneys and Heart, strengthens the Bones, Nourishes Blood, etc., by enhancing the functions of liver, kidney and heart channels.
Ingredients
1. Collagen
2. Aspartate
3. Threonine
4. Methionine
5. Phenylalanine
6. Leucine
7. Etc.
Health Benefits
1. Proliferation-promoting effects
In order to identify active components of PT involved in promoting proliferation of MSCs, PT was extracted with ethyl acetate and separated by silica gel column chromatography with gradient elution. Sixteen (Ts-1∼16) components were obtained, found that Ts-12 could induce the proliferation compared with control group (p<0.05), while Ts-4 exhibited inhibitive effect. The chemical components of PT which regulated the proliferation of rMSCs were investigated by GC-MS, HPLC and nine standard compounds. according to “Chemical components in extracts from Plastrum Testudinis with proliferation-promoting effects on rat mesenchymal stem cells” by Wang TT, Chen W, Zeng HP, Chen DF.(1)
2. Apoptosis
In the observation of the inhibitive effects of Plastrum testudinis Extracts (PTE) on 6-Hydroxydopamine (6-OHDA) induced PC12 cells apoptosis and explore its mechanism,
found that PTE can inhibit the apoptosis of PC12 induced by 6-OHDA in a dose dependent manner, and its mechanism maybe associated partially with up-regulating BCL-X/L signaling pathway, according to `[Effects and mechanism of Plastrum testudinis extracts on PC12 apoptosis].[Article in Chinese]`by Liu Y, Wu YL, Cao JH, Chen DF, Zhou JH, Deng RD.(2)
3. Etc.
Side Effects
1. Do not use the herb in case of yang or spleen deficiency
2. Do not use if you have cold or flu
3. Do not use the herb in newborn, children or if you are pregnant or breast feeding without consulting first with the related field specialist.
4. Etc.
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Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/22339978
(2) http://www.ncbi.nlm.nih.gov/pubmed/21823458
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