Antioxidant Lycopene Reduces Risk and Treatment of Gastric Ulcer in Vivo

By Kyle J. Norton

The stomach located between the esophagus and the small intestine is a muscular, hollow and important organ of the digestive tract.

The stomach plays a critical role to assist the digestive system in digesting foods by secreting acid and enzymes.

Gastric or stomach ulcer is a condition of localized tissue erosion in the lining the stomach.

Most common symptoms of gastric ulcers are abdominal pain, bloating, septic shock, dyspepsia, and blood in the stool due to bleeding, unintended weight loss and loss of appetite and gastrointestinal discomforts.

Some patients may also experience symptoms of mood disorder, leading to reduced quality of life in many patients.

The imbalance between stomach acid and upper GI tract mucosa is the main cause of the condition onset associated with the use of certain medication, including aspirin, and non-steroidal anti-inflammatory drugs, Helicobacter pylori infection and chronic gastritis.

Epidemiologically, periodontal disease, aging, smoking, long-term use of mechanical ventilation and critical illness are at an increased risk of gastric ulcer.

Dr. Haruka Fujinami lead scientist in the examination of long term intake of conventional medicine in the risk of gastric ulcer wrote, "The rates of Helicobacter pylori (H. pylori) infection were significantly low (P = 0.039), while the proportion of nonsteroidal anti-inflammatory drugs (NSAIDs) users and vascular disease significantly increased over the period studied (P = 0.034 and P = 0.04, respectively)".

And, "It’s found that the primary cause of peptic ulcer bleeding changed from H. pylori infection to use of NSAIDs over the 7-year period of study. It seems that the number of low-dose aspirin users has increased with the increase in the proportion of vascular disease".

The results strongly suggested if you are a long-term user of nonsteroidal anti-inflammatory drugs, your risk of gastric ulcer is significantly higher.

Lycopene is a phytochemical found in tomato in the class of carotenoid, a natural pigment with no vitamin A activity found abundantly in tomatoes and other red fruits and vegetables, such as red carrots, watermelons, and papayas,

Tomatoes provide about 80% of the lycopene in the world diet. In plants, lycopene protects the host against excessive photodamage and performs various functions in photosynthesis.

On finding a potential compound for the treatment of ulcers, researchers examined the protective effects of lycopene on an indomethacin-induced gastric ulcer model.

The study included a total of 42 adult male Wistar rats induced by gastric ulcer by divided into six groups of seven animals as follows: control, indomethacin, lansoprazole, lycopene 10 mg/kg, lycopene 50 mg/kg and lycopene 100 mg/kg.

According to the tested analysis, the % Tail DNA and Mean Tail Moment in the gastric ulcer group were significantly decreased by the treatment of lycopene at the dose of 100 mg/kg, compared to other treatment groups.

Furthermore, the treatment of lycopene at the dose of 100 mg/kg not only decreased the increased levels of malondialdehyde and myeloperoxidase in the gastric ulcer group but also increased the antioxidant enzymes in the gastric tissue without affecting the levels of catalase.

Based on the findings, researchers said, "lycopene might have a protective effect against indomethacin-induced gastric ulcer and oxidative stress in rats".

Taken altogether, lycopene found in tomato may be considered supplements for the prevention and treatment of gastric ulcer, pending on the confirmation of the larger sample size and multicenter human study.

Intake of lycopene in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) The effects of lycopene on DNA damage and oxidative stress on indomethacin-induced gastric ulcer in rats by Boyacioglu M1, Kum C2, Sekkin S2, Yalinkilinc HS2, Avci H3, Epikmen ET3, Karademir U. (PubMed)
(2) A study of the changes in the cause of peptic ulcer bleeding by Haruka Fujinami, Takahiko Kudo, Ayumu Hosokawsa, Kohei Ogawa, Takako Miyazaki, Jun Nishikawa, Shinya Kajiura, Takayuki Ando, Akira Ueda, and Toshiro Sugiyama. (PMC)

Herbal Turmeric Reduces Risk of Chronic Inflammatory Diseases

By Kyle J. Norton

Inflammation is a process of the immune system that responds to harmful pathogens.

Inflammation can be acute or chronic. In the acute phase of infection, the immune system after receiving information from the neurons, macrophages, the largest white blood cells in the first line of defense stimulate the production of blood palette to cover the wound and the production of inflammatory cytokines to kill off micro-organisms, leading to symptoms of fever, redness, and swelling.

However, in some cases, the overproduction of proinflammatory cytokines may damage nearby healthy cells and tissues, causing the formation of scars.

In severe cases, a protein with duo functions in the production of pro and anti-inflammatory cytokines which produce anti-inflammatory cytokines under normal condition also switch to produce pro-inflammatory cytokines.

Most cases of acute inflammatory are resolved within a few days without causing damage to the wound tissues.

 However, if the immune first line of defense can not completely destroy the invaders within a period of 3 to 8 weeks, it will compromise, leading to low-grade chronic inflammation.

Diseases associated with low-grade chronic inflammation include diabetes, cardiovascular disease, and cancer.

Dr. in the examination of the etiology of  chronic inflammation (CI) suggested that CI can result from the following:
* Failure of eliminating the agent causing an acute inflammation such as infectious disease induced organisms 
* Long-term exposure to a low level of a particular irritant or foreign materials that cannot be eliminated by an enzymatic breakdown in the body including substances or industrial chemicals.

* An autoimmune disorder caused by the immune system that attacks healthy tissue,  such as rheumatoid arthritis, systemic lupus erythematosus (SLE)

* Recurrent episodes of acute inflammation. 

* Inflammation that causes oxidative stress and mitochondrial dysfunction such as advanced glycation end products (AGEs).

Conventionally, treatment of acute phase inflammation is to manage inflammation and prevent the risk of long-term damage, including anti-inflammatory nonsteroidal anti-inflammatory drugs (NSAIDs) which can be bought without a prescription.

Turmeric is a perennial plant in the genus Curcuma, belongings to the family Zingiberaceae, native to tropical South Asia.

The herb has been used in traditional medicine as an anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and to treat flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.

On findings a potential compound for the treatment of chronic diseases, researchers examined the efficacy of turmeric on continued oxidative stress and oxidative damage that lead to chronic inflammation in the mediation of most chronic diseases.

At the molecular level, turmeric showed a significant anti-inflammatory activity by suppressing the proteins associated with the production of pro-inflammatory cytokines, including the NF-κB and COX-2.

Furthermore, the proteins associated with the response to cytokines and growth factors such as signal transducer and activator of transcription 3 was also inhibited by the injection of turmeric.

Moreover, the administration of turmeric also inhibited the production of ROS by promoting the production of antioxidants enzymes such as nrf2, a protein that regulates the expression of antioxidant proteins that protect against oxidative damage.

Furthermore, numerous studies also indicated that curcumin not only is highly potent against the antimicrobial disease but also inhibited the onset of various chronic diseases including cancers, diabetes, obesity, cardiovascular, pulmonary, neurological and autoimmune diseases.

As of today, over 100 different clinical trials also showed that curcumin is safe, tolerable and effective against various chronic diseases in humans.

Taken altogether, turmeric processed abundantly bioactive compound curcumin may be considered supplements for the prevention and treatment of chronic inflammatory diseases pending to the confirmation of the larger sample size and multicenter human study.

Intake of turmeric in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

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Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Curcumin, the golden nutraceutical: multitargeting for multiple chronic diseases by Kunnumakkara AB1, Bordoloi D1, Padmavathi G1, Monisha J1, Roy NK1, Prasad S2, Aggarwal BB. (PubMed)
(2) Curcumin, inflammation, and chronic diseases: how are they linked? by He Y1, Yue Y2, Zheng X3,4, Zhang K5, Chen S6, Du Z. (PubMed)
(3) Chronic Inflammation by Roma Pahwa; Ishwarlal Jialal. (NCBI)

Cranberry Inhibits Lung Cancer Cells Initiation and Progression

By Kyle J. Norton

The lung formed part of the respiratory system is a vital organ located near the backbone on either side of the heart with functions of inhaling oxygen from the air then transporting them to the bloodstream and exhaling carbon dioxide from the bloodstream.

Lung diseases are a class of conditions associated with reduced function of the lung, including lung cancer.

Lung cancer is a medical condition associated with abnormal growth of the cells in the lung's tissue that begins in the cells on the surface of the inner lining tissues of the lung due to the alternation of cell DNA.

Most common form of primary lung cancer is derived from epithelial cells. 

In the US, lung cancer is the leading cause of cancer deaths. According to the statistics from the American Cancer Society, in 2019, about 228,150 new cases of lung cancer, including 116,440 in men and 111,710 in women will be diagnosed in the US.

Sadly, lung cancer also causes the death of 142,670 American death, including 76,650 in men and 66,020 in women in the same year.

The lifetime risk of lung cancer in a man is 6.7% compared to 5.9% in a woman.

The exact causes of lung cancer are not known. However, epidemiologically, smoking tobacco, second-hand smoke, radon, asbestos, occupational exposure to certain chemicals, personal or family history of lung cancer and lung disease and exposure to radiation are some major factors found in patients with lung cancer.

Dr. Ozlü T, the lead scientist wrote, " Tobacco use has been reported to be the main cause of 90% of male and 79% of female lung cancers. 90% of deaths from lung cancer are estimated to be due to smoking".

And, "The risk of lung cancer development is 20-40 times higher in lifelong smokers compared to non-smokers. Environmental cigarette smoke exposure and different types of smoking have been shown to cause pulmonary carcinoma. DNA adducts, the metabolites of smoke carcinogens bound covalently with DNA, are regarded as an indicator of cancer risk in smokers".

Cranberry is an evergreen dwarf shrub, genus Vaccinium, belongings to the family Ericaceae, native to Northern America and Southern Asia. Because of its health benefits, cranberry has been cultivated in some parts of the world for commercial profit and used in traditional and herbal medicine to treat wounds, urinary disorders, diarrhea, diabetes, stomach ailments, and liver problems.

On finding a potential compound for the protection of lung cell integrity, researchers examined the effect of the efficacy of proanthocyanidin-rich cranberry fraction (PAC) on lung cancer.

According to the tested analysis, NCI-H460 human lung cancer cells treated with 50 µg/mL PAC or vehicle for 6 hours, PAC exerted a significant activity in the regulation of apoptosis, regulation of programmed cell death, positive regulation of cell death, positive regulation of apoptosis, and apoptotic mitochondrial changes.

Moreover, also NCI-H460 human lung cancer cells treated with 50 µg/mL PAC showed a strong effect on cancer cell metabolism, protein modifications, and cell cycle by inhibiting the M phase of the mitotic cell cycle, mitosis, M phase, cell cycle checkpoint, and regulation of cell cycle process.

More precisely,  PAC induced lung cancer cell apoptosis and anti-proliferative activity through cell cycle arrest.

Furthermore, PAC treatment also enhanced the levels of glutathione S-transferases associated

with blocking cancer cell metastasis.

PAC treatment also down-regulated DNA metabolism, cell cycle, meiosis, mitosis and interestingly oncogenesis signaling.

PAC treatment also inhibited the alternation of ErbB receptors and signaling pathways and mTOR signaling pathways mutated in lung tumors, involved in cancer development and progression

Taken altogether, cranberry used conjunction with other remedies may be considered a remedy for the prevention and treatment of lung cancer, pending to the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Cranberry proanthocyanidins mediate growth arrest of lung cancer cells through modulation of gene expression and rapid induction of apoptosis by Kresty LA1, Howell AB, Baird M. (PubMed)
(2) Smoking and lung cancer by Ozlü T1, Bülbül Y. (PubMed)

Turmeric Inhibits Hair Loss and Promotes Hair Growth in Men

By Kyle J. Norton

Every day the scalp loses about 100 hairs and they will grow back in 5-6 weeks. However, in older men, hair loss was associated with the increase of levels of by-product prolactin of testosterone-induced the conversion of testosterone to gihydro-testosterones DHT, a leading cause in the promotion of hair growing back thinner or not grown back at all.

The presence of gihydro-testosterones DHT shrinks the follicles causing hair thins and hair receding at the forehead, crown, and temple for men and thins over the entire scalp for women. 

There are many factors involved in the loss of hair.  Aging, nutrient deficiency, genetic proposition, smoking, and unhealthy diet are some of the most common risk factors that cause hair loss in the Western world.

Conventionally, Minoxidil, a topical medicine approved by The U.S. Food and Drug Administration (FDA) was found to stop hairs from getting thinner and stimulate hair growth on the top of the scalp with a number of side effects.

Dr. Rossi A, the lead scientist at the University Sapienza of Rome in the evaluation of the effects of
oral Minoxidil wrote, " Minoxidil is a potassium channel opener, causing hyperpolarization of cell membranes and it is also a vasodilator, it is speculated that, by widening blood vessels and opening potassium channels, it allows more oxygen, blood, and nutrients to the follicle".

And, "The most common adverse reactions of the topical formulation are limited to irritant and allergic contact dermatitis on the scalp. There have been cases of allergic reactions to the nonactive ingredient propylene glycol, which is found in some topical solution especially if they are galenic".

Therefore, if you are using the aforementioned product for the treatment of hair loss, please make sure you know all the side effects for preventive measure.

Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia.

The herb has been used in traditional medicine as anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and to treat flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.

With an aim to find a potential ingredient for the treatment of hair loss, researchers evaluated the efficacy of 5% hexane extract of Curcuma aeruginosa (turmeric), a botanically derived inhibitor of 5α-reductase and 5% minoxidil in the treatment of androgenetic alopecia.

The study included 87 men with androgenetic alopecia (AGA) randomized to receive 5% Curcuma aeruginosa, 5% minoxidil, combination formulation (5% hexane extract of Curcuma aeruginosa + 5% minoxidil) or placebo, twice daily for 6 months.

According to the tested assay, the combined treatment group showed statistically significant improvements of hair regrowth, and hair shedding in a global photographic review of all subjects, compared to the single treatment of groups and placebo.

In other words, treatment with 5% minoxidil and 5% C. aeruginosa extract shoed some degrees of hair regrowth without affecting hair shedding.

No adverse \effects were found during the course of the experiment.

Based on the results, researchers wrote in the final report, "In men with hair loss in the vertex area of the scalp, the combination of 5% hexane extract of C. aeruginosa and 5% minoxidil slowed hair loss and increased hair growth".

Taken altogether, turmeric used alone or combined with minoxidil may be considered supplements for the prevention and treatment of alopecia areata, pending to the confirmation of the larger sample size and multicenter human study.

Intake of turmeric in the form of supplement should be taken with extreme care to prevent overdose acute liver toxicity.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Curcuma aeruginosa, a novel botanically derived 5α-reductase inhibitor in the treatment of male-pattern baldness: a multicenter, randomized, double-blind, placebo-controlled study by Pumthong G1, Asawanonda P, Varothai S, Jariyasethavong V, Triwongwaranat D, Suthipinittharm P, Ingkaninan K, Leelapornpisit P, Waranuch N. (PubMed)
(2) Germacrene Analogs are Anti-androgenic on Androgen-dependent Cells by Srivflai J, Khorana N, Waranuch N, Wisuitiprot W, Suphrom N, Suksamrarn A, Ingkaninan K. (PubMed)
(3) Minoxidil use in dermatology, side effects and recent patents by Rossi A1, Cantisani C, Melis L, Iorio A, Scali E, Calvieri S. (PubMed)

Healthy Food Onion Protects the brain Neuron Against Anxiety and Depression Induced by Stress

By Kyle J. Norton

Neurological disorders are a class of diseases of the nervous system caused by structural, biochemical or electrical abnormalities in the brain, spinal cord or nerves.

Neurodegenerative disease is a type of neurological disorder associated with the progressive loss of neuron in the brain caused by several mechanisms, including toxicity and oxygen deficiency.

Anxiety is a natural response to the stress involved in the feeling of fear of the event and event outcome.

Depression is a common and serious psychological condition associated with the negative feeling, that affects the way of thinking and acting.

Besides neurodegenerative disease, the most common types of neurological disorder are 

epilepsy, multiple sclerosis, and migraines.

According to statistics provided by the Psychological Guide, neurological disorders affect millions of people around the world, including 326 million who suffer migraines.

There is no single cause of the neurological disorder. Some researchers suggested that unhealthy lifestyle, genetic preposition, nutrient, infection, and physical injury are some of the most prevalent factors found in most patients.

If you have experienced symptoms of seizures, difficulty reading, and writing, poor cognitive abilities, unexplained pain, muscle weakness, and decreased alertness, mood swing,  depression and delusions, you may have some form of neurological disorder. Please check with your doctor to rule out the possibility

The onion is a plant in the genus Allium, belonging to the family Alliaceae, a close relation of garlic. It is often called the "king of vegetables" because of its pungent taste and found in a large number of recipes and preparations spanning almost the totality of the world's cultures. 

Depending on the variety, an onion can be sharp, spicy, tangy, pungent, mild or sweet.

On finding a potential compound for the prevention of stress-induced psychological syndromes researchers examined the effects of onion (AC) on single immobilization stress-induced biochemical and behavioral changes.

The experiment included mice in the test group were treated with AC powder (200 mg/kg/day), dissolved in water, while the control group received drinking water for 14 days.

According to the results after 14 days of treament that control and AC treated mice were further divided into unstressed and stressed groups,

* Administration of AC showed significant activity in attenuating the immobilization stress-induced behavioral deficit.

* AC also improved the memory performance was observed in stressed mice in maze test (EPM).

* AC pretreatment group also demonstrated a strong reduction of brain lipid peroxidation, increased antioxidant enzymes (SOD, CAT, GPx) and reduced acetylcholinesterase (AChE) levels.

In other words, the injection of AC inhibited the brain oxidative stress in the tested mice by promoting the production of antioxidants enzymes in the host.

Based on the finding, researchers suggested, "a role of antioxidant enzymes in the attenuation of 2-h stress-induced anxiety and depression, and enhanced cognitive function as well by AC".

More precisely, AC protected the brain neurons integrity and viability against the parameters induced by stress.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Administration of Allium cepa L. bulb attenuates stress-produced anxiety and depression and improves memory in male mice by Samad N1, Saleem A. (PubMed)

Herbal Ashwagandha Exerts Cytotoxicity Against Leukemia in Vitro

By Kyle J. Norton

Leukemia is a condition characterized by an abnormal increase of white blood cells produced by the bone marrow and/or the lymphatic system. Depending on the malignant granulocytes or lymphocytes, leukemia is classified into myelogenous or lymphoblastic leukemia.

Bone marrow, containing two main types of stem cell is soft tissue inside the hollow center of the major bone, including the spine, pelvis, underarm, leg. etc. with the main function of generating blood cells.

Believe it or not, the bone marrow produces 200 billion new red blood cells every day, to replace the blood cells that die off, along with white blood cells and platelets.

According to the statistics provided by the leukemia research, leukemia is diagnosed 10 times more often in adults than children. Approximately, each year the disease causes death 68,000 American.

Acute leukemia is a condition caused by a rapid increase in the numbers of extreme immature white blood cells which appear in the bloodstream into other parts of the body, including tissue and organs, including acute lymphoblastic leukemia (ALL), acute lymphocytic leukemia (ALL) and acute myeloid leukemia (AML).

In ALL, lymphocytes appear immature in the bloodstream. Acute lymphoblastic leukemia (ALL) is the most common children forms of leukemia with about 80% of all cases.

Chronic leukemia is a condition of the slow but still excessive build-up of relatively mature abnormal white blood cells. the condition has a tendency to spread slowly to other parts of the body through the bloodstream and/or lymphatic system, including chronic lymphocytic leukemia (CLL) and chronic myelogenous leukemia (CML).

Ashwagandha also is known as Withania somnifera is a nightshade plant in the genus of Withania, belonging to the family Solanaceae, native to the dry parts of India, North Africa, Middle East, and the Mediterranean.

The herbal medicine has been considered as Indian ginseng and used in Ayurvedic medicine over 3000 years to treat tumors and tubercular glands, carbuncles, memory loss, and ulcers and considered as anti-stress, cognition-facilitating, anti-inflammatory, and anti-aging herbal medicine.

On finding a potent compound for the treatment of leukemias, researchers explored the antileukemic activity of the dimethyl sulfoxide extract obtained from the roots of W. somnifera (WE).

On a human T-lymphoblastoid cell line, WE exerted a significant cytostatic and cytotoxic activity against the tested cell line observed by the differentiation of the different flow cytometric assays.

Furthermore, WE cytotoxic and cytostatic potential was atrribited to the effect involving in immunogenic cell death (ICD) observed in dying cancer cells that release damage-associated molecular patterns.

Furthermore, WE also promoted the intracellular Ca(2+) accumulation that alters cancer initiation and the generation of reactive oxygen species to induce cancer cell apoptosis.

In other words, the tested extract processed genotoxic potential. against leukemia cells in vitro.

Based on the findings, researchers said, "Since the use of Withania is suggested in different contexts including anti-infertility and osteoarthritis care, its genotoxicity should be carefully considered for an accurate assessment of its risk-benefit profiles".

Taken altogether, Ashwagandha may be considered a functional herb for the prevention and treatment of leukemia, pending to the result of larger sample size and multicenter study



Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You  How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Withania somnifera Induces Cytotoxic and Cytostatic Effects on Human T Leukemia Cells by Turrini E1, Calcabrini C2, Sestili P3, Catanzaro E4, de Gianni E5, Diaz AR6, Hrelia P7, Tacchini M8, Guerrini A9, Canonico B10, Papa S11, Valdrè G12, Fimognari C. (PubMed)

The 47 Health Benefits of Onion and Counting, Researchers Say

By Kyle J. Norton

The onion is a plant in the genus Allium, belongings to the family Alliaceae, a close relation of garlic. It is often called the "king of vegetables" because of its pungent taste and found in a large number of recipes and preparations spanning almost the totality of the world's cultures.


Depending on the variety, an onion can be sharp, spicy, tangy, pungent, mild or sweet.

1. Phytochemical Quercetin Isolated from Onion Inhibits Parameters Involved in Oral cancer Developing
2. Whole Food Onion Kills Renal Cancer Cells in Vitro
3. Onion Blocks the Initiation of Prostate Cancer
4. Healthy Food Onion Processes Immune-modulatory Activity for the Needs of the Body
5. Healthy Food Onion, A Natural Prevention and Treatment of Insulin Resistance
6. Healthy Food Onion, the Best Natural Anti-Hyperlipidemic Food
7. Healthy Food Onion Inhibits the Initiation and Progression of Gastrointestinal Tract Cancer
8. Healthy Food Onion Protect the Liver cells Against Alcoholic Cytotoxicity
9. Healthy Food Onion, the Natural Prevention and Treatment of Colorectal Cancer
10. Onion, the Best Liver Protective Ingredient
11. Whole Food Onion Protects the Endometrial Cells Integrity Against the Risk of Endometriosis
12. Healthy Food Onion Kills Colon Cancer in Vitro
13. Healthy Food Onion Prevents the Onset of Hyperglycemia
14. Organic Growth Onion Processed Higher Antioxidant Contents than Conventional Growth Onion
15. Healthy Food Onion Processes Anti-Parasitic Property
16. Onion, the Natural Anti Ovarian Cancer Functional Food
17. Healthy Food Onion Block Cancer Cells Proliferation
18. Healthy Food Onion Protects the Cell DNA Against the Risk of Ovarian Cancer
19. Healthy Food Onion, The Natural Anti High Blood Pressure Whole Food
20. Healthy Food Onion Promotion the Vascular Protection
21. Healthy Food Onion Protects the Healthy Cell Against Cyto and Geno-Toxicity
22. Whole Food Onion Protects the Stomach Against Stomach Cancer
23. Onion, the Natural Vasorelaxant Remedy
24. Healthy Food Onion Inhibits Invasive Osteosarcoma in Vitro
25. Healthy Food Onion Protects the vascular endothelial Functioning Against Cardiovascular Disease
26. Whole Food Onion's Quercetin inhibits the Effect of Hypertension Against the Risk of Cardiovascular Disease in Overweight and Obese Individuals
27. Healthy Food Onion, the Anti-Hypertensive Remedy
28. Whole Food Onion Anti-Parasitic, Bacterial, and Fungal Activity
29. Healthy Food Onion Reduces the Risk of Head and Neck Cancer
30. Onion in the Prevention and Treatment of type 2 diabetes
31. Healthy Food Onion, the Potent Antioxidants
32. Healthy Food Onion Reduces Risk of Endometrial Cancer
33. Healthy Food Onion in the Inhibition of Angiogenesis
34. Whole Food Onion, the Best Anticancer Functional Food
35. Onion Promotes Healthy Gut Microbiota
36. Healthy Food Onion Protects Protect the Heart Against Chemo-Cardiotoxicity
37. Healthy Food, Not All Onions Process Antithrombotic, and Thrombolytic Activity
39. Onion, the Anti- Platelet Aggression Functional Remedy
40. Onion, the Best in the Management of Surgical Wounds
41. Healthy Food Onion Protects the Upper Aerodigestive Tract (UADT) Against the Risk of Cancer
42. Health Food Onion Processes Anti-Atherogenic Property
43. Healthy Food Onion Processed Neuro-Protective Activity
44. Whole Food Onion, A Natural Prevention of Pancreatic Cancer, Scientists Say
45. Healthy Food Onion Risk Reduces The Risk of Esophageal cancer
46. Onion the Natural Alternative Antibiotic
47. Healthy Food Onion the Anti Acute and Chronic Inflammatory Functional Food

and Counting

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.