Thursday 18 June 2020

Broccoli, the Potential Anti-Prostate Cancer Healthy Food

By Kyle J. Norton

Prostate warped around the around a tube (the urethra) is a gland of the male reproductive system found in front of the rectum and just below the bladder and responsible for making some of the semen that carries sperm.

Prostate cancer is a condition in which the cells of the prostate have become cancerous, causing abnormal cell growth which spread to the distant parts of the body. Most prostate cancers are slow-growing and enlarged prostate and prostate cancer may be detected during the Physical (rectum) exams.

Primary prostate cancer normally starts from the cell on the surface of the inner lining of the prostate tissue and gradually spreads to the deeper part of the prostate.

At the early stage, patients may not experience any symptoms, However, at the advanced stage, prostate cancer can induce symptoms of blood in the urine, frequent urination and urinary difficulty.

The cancer cells at this stage can also travel a distance away from the prostate to invade other healthy tissue and organ, leading secondary metastasis tumors.

According to the Canadian Cancer Society, in 2017, 21,300 men were diagnosed with prostate cancer, represented 21% of all new cancer cases and 4,100 men died from prostate cancer, and 10% of all cancer deaths.

The 5 years survival rate of localized prostate cancer is 100% and 98% of that of survivors are alive after 10 years compared to the advanced stage of only 31%.

More than 80% of prostate cancers are diagnosed in men who are 65 or older.

Therefore, men who are at higher risk of prostate cancer due to family history and increase in age and inherited gene changes should have their prostate gland checked annually.

Broccoli is a mustard/cabbage plant, belong to the family Brassicaceae. The veggie has large flower heads, usually green in color and the mass of flower heads surrounded by leaves and evolved from a wild cabbage plant on the continent of Europe.

On finding a potential plant that processes anticarcinogenic activity, researchers examined the effects of consuming broccoli soup on prostate tissue.

The study included 18 men scheduled for transperineal prostate biopsy recruited into a 4-week parallel single-blinded diet supplementation study (NCT02821728), with 9 men supplemented their diet with three 300 mL portions of a broccoli soup each week for four weeks prior to surgery.

According to the analyses of the prostate, biopsy tissues reveal no detectable levels of glucosinolates and derivatives on the baseline.

Where Glucosinolates (GLS) are secondary plant metabolites in cruciferous vegetables with a function to break-down products, prevention of cancer in animal and cell studies.

Injection of the supplementation of SMCSO demonstrated significantly higher levels of glucosinolates and derivatives in the tissue of men in the supplementation arm.

The urinary assay also suggested that SMCSO was found in blood and urine samples from a previous intervention study with the identical broccoli soup.

Based on the findings, researchers wrote, " The consequences of SMCSO accumulation in prostate tissues and its potential role in the prevention of prostate cancer...

In other words, the intake of SMCSO over a short period of time of 4 weeks reduces the risk of prostate cancer.
Taken altogether, the consequences of these results suggest that the broccoli process the potential anticarcinogenic activity by upregulating the gene associated with xenobiotic metabolism, pending to the confirmation of the larger sample size and multicenter human study.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Accumulation of Dietary S-Methyl Cysteine Sulfoxide in Human Prostate Tissue by Coode-Bate J1, Sivapalan T1, Melchini A1, Saha S1, Needs PW1, Dainty JR2, Maicha JB1, Beasy G1, Traka MH1, Mills RD3, Ball RY4, Mithen RF. (PubMed)

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