Monday 26 December 2016

The holistic Prevention, Management and Treatment of Dementia - Common antioxidants (scavengers) Bilirubin

Kyle J. Norton (Scholar) 
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


                                 Dementia

Dementia is defined as neuro degeneration syndrome among elder, affecting memory, thinking, orientation, comprehension, calculation, learning capacity, language, and judgement over 47 millions
of worldwide population, mostly in the West. The evaluation of the syndrome by holistic medicine has been lacking, especially through conventional medicine research and studies.
                           

           Common antioxidants (scavengers) Bilirubin

The expression of added to a mixture in order to remove or de-activate impurities and unwanted oxygen in the cellular level for reduced risk of oxidative stress defence in plants and animals.


1. Bilirubin
Bilirubin is a prosthetic group with a unique function in breaking down molecules into smaller units for releasing energy, excreted in bile and urine(263). As a cellular antioxidant, it protected against diseases associated with oxidative stress, through mildly elevated serum bilirubin levels and activation of heme oxygenase(264) and reverted to biliverdin, a green tetrapyrrolic bile pigment, through antioxidant redox cycle in inhibition of the effects of mutagens when oxidized(265). A significant reduction of levels ofbilirubin, has shown to associate to patients with Alzheimer's disease(AD)(266).


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References
(263) New insights in bilirubin metabolism and their clinical implications b Sticova E1, Jirsa M.(PubMed)
(264) Bilirubin chemistry and metabolism; harmful and protective aspects by VĂ­tek L1, Ostrow JD.(PubMed)
(265) Direct Antioxidant Properties of Bilirubin and Biliverdin. Is there a Role for Biliverdin Reductase? by Jansen T1, Daiber A.(PubMed)
(266) Decreased plasma antioxidants in patients with Alzheimer's disease. by Kim TS1, Pae CU, Yoon SJ, Jang WY, Lee NJ, Kim JJ, Lee SJ, Lee C, Paik IH, Lee CU.(PubMed)

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