Thursday, 15 December 2016

The holistic Prevention, Management and Treatment of Dementia - The Antioxidant enzymes Catalase

Kyle J. Norton (Scholar) 
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


Dementia is defined as neuro degeneration syndrome among elder, affecting memory, thinking, orientation, comprehension, calculation, learning capacity, language, and judgement over 47 millions
of worldwide population, mostly in the West. The evaluation of the syndrome by holistic medicine has been lacking, especially through conventional medicine research and studies.

                           The Antioxidant enzymes Catalase

Antioxidant enzymes, chemical substances found in plants, protect the body from damage of free radicals by terminating the chain reactions through removing free radical intermediates and inhibiting oxidation reactions.

1. Catalase
Catalase is an enzyme, found in most living organisms exposed to oxygen for action of converse hydrogen peroxide (free radicals)(226) to water and oxygen. The antioxidants showed to protect cells against the toxic effects of hydrogen peroxide in pathogenesis of oxidative stress-related diseases(222) inducted early stages of aggregation of the amyloid peptides(225), including neurodegeneration(224) such as Alzheimer's diseas(223).

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(222) Human catalase, its polymorphisms, regulation and changes of its activity in different diseases. by Kodydková J1, Vávrová L1, Kocík M1, Žák A1.(PubMed)
(223) Systemic oxidative stress and conversion to dementia of elderly patients with mild cognitive impairment. by Cervellati C1, Romani A1, Seripa D2, Cremonini E1, Bosi C3, Magon S3, Bergamini CM1, Valacchi G4, Pilotto A5, Zuliani G3.(PubMed)
(224) Neurodegeneration through oxidative stress: monitoring hydrogen peroxide induced apoptosis in primary cells from the subventricular zone of BALB/c mice using field-effect transistors. by Koppenhöfer D1, Kettenbaum F1, Susloparova A1, Law JK1, Vu XT1, Schwab T1, Schäfer KH1, Ingebrandt S2.(PubMed)
(225) Hydrogen peroxide is generated during the very early stages of aggregation of the amyloid peptides implicated in Alzheimer disease and familial British dementia. byTabner BJ1, El-Agnaf OM, Turnbull S, German MJ, Paleologou KE, Hayashi Y, Cooper LJ, Fullwood NJ, Allsop D.(PubMed)
(226) Development of a new catalase activity assay for biological samples using optical CUPRAC sensor. by Bekdeşer B1, Özyürek M1, Güçlü K2, Alkan FÜ3, Apak R1.(PubMed)

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