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Tuesday, 7 April 2015

The Holistic prevention, management and treatment of Polycystic Ovarian Syndrome: The Top 5 Anti inflammatory Foods

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By Kyle J. Norton Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
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Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


                                         Polycystic Ovarian Syndrome


Polycystic Ovarian Syndrome is defined as endocrinologic diseases among reproductive-age women caused by undeveloped follicles clumping on the ovaries that interferes with the function of the normal ovaries associated with a high risk for metabolic disorder(1) as resulting of enlarged ovaries(2), leading to hormone imbalance(excessive androgen and anti-müllerian hormone (AMH) )(1)(3)(4)(5), induced Hirsutism(6)(7), reproductive disorder(10(12)), risks of type 2 diabetes(9)(10)(11), metabolic syndrome(10)(12) and early cardiovasular disease(8)(13), acne(10)(14), endometrial cance(18)(19),weight gain and obesity(15)(16)(17). The syndrome effects over 5% of women population or 1 in 20 women.
Unfortunately, according to studies, women with PCOs after the reproductive age, are associated to  continuously increase risk of type II diabetes, with no increasing altered glucose tolerance(20), CVD and hypertension(21).



                               The prevention and management 

Polycystic ovary syndrome (PCOS) is unpreventable in Western medicine. Early diagnosis and treatment  may reduce risk of its complications, including infertility, metabolic syndrome, obesity, diabetes, cardiovascular diseases, stroke, etc.

Although PCOS cannot be completely avoided, strengthening immunity has shown a significant reduction of chronic inflammatory diseases(266)(267)(268).


                             The Top 5 Anti inflammatory Foods 

According to Medical University Innsbruck, the interactions between diet, immunity, and the microbiota, may be necessary for the develop food-based approaches to prevent or treat many diseases(285).
1. Garlic
Garlic (Allium sativum) is a species in the onion genus, belongings to family Amaryllidaceae, native to central Asia, used popularly in traditional and Chinese medicine to treat common cold and flu(306), digestive disorders(313), diabetes(322)(323)(324), therosclerosis,(325), cardiovascular diseases(326)(327), strengthen immunity(319) against irregular cell growth suach as tumors(314)(315)(316)(317)(318), bacterias(310)(311)(312), fungii(310)(311) and virus(320)(321), lower blood pressure(328)(329)(330) and cholesterol levels(310)(331), etc. Recent studies also showed that garlic exhibits its anti-inflammatory effects against chronic inflammatory disease(307)(308)(309) through phytochemical allicin(307) and other machenisms(308)(309).

2. Ginger
Ginger (Zingiber officinale) or ginger root is the genus Zingiber, belongings to the family Zingiberaceae, native to Tamil,  used in traditional and Chinese medicine to treat dyspepsia(332)(333), gastrointestinal disorder(334) such as nausea and vomiting(335), constipation(337), gastric ulcer(338),.... edema(339)(340), difficult urination(340), colic and diarrea(341), etc.... Strong evidences in Western studies also showed that ginger also induce some mechanisms for treatment of pschological symptoms, such as anxiety(342). depression(343),..., diabetes(344)(345), hypertension(346), irregular cell growth  such as tumors(347)(348)(349), and rheumatoid arthritis(352) and  osteoarthritis(336) through its anti inflammatory, antioxidant and immune-modulatory effects(346)(350)(351), speed up wounding healing(352)(353), etc.

3. Turmeric
Turmeric is a perennial plant in the genus Curcuma, belongings to the family Zingiberaceae, native to tropical South Asia. The herb has been used in traditional medicine as anti-oxidant(354)(355), hypoglycemic(356)(357), colorant(358), antiseptic(359)(360), wound healing(361) agents, and to treat flatulence(362), bloating(363), and appetite loss(364), ulcers(365), eczema(366), inflammations(367), etc. Epidemiological studies also found that the efficacy of turmeric for treatment for diabetes(369)(370), microbial infection(359)(371)(372), gastrointestinal diseases(359)(373) and irregular cell growth such as cancer(374)(375)(376) through its anti inflammatory(367)(368), antioxidant(377)(378) and immunmodulatory(379)(380) activities. 

4. Green tea
Green tea contains more amount of antioxidants than any drinks or food with the same volume, and is the leaves of Camellia sinensis, undergone minimal oxidation during processing, originated from China. Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years. Because of their health benefits, green tea has been cultivated for commercial purposes all over the world. Epidemiological studies suggested that green tea consists many pharmateutical properties, including anti cancers(381)(382), anti diabetes(383)(384), induced weight loss(385)(386)anti aging and longevity(387)(388), anti allergy(389)(390), anti micro-organisms(391)(392), anti lipidemic(393)(394). anti stroke(385)(396) and cardiovascular diseases, through its antioxidant(397)(398), anti inflammatory(399)(400) and immune modulatory(401)(402) activities.

5. Shiitake mushrooms
Shiitake mushroom is an edible mushroom, genus Lentinula, belonging to family Marasmiaceae, native to East Asia and widely cultivated for consumption for its health benefits and commercial purpose in many Asian countries. The herb has been used in traditional medicine as blood tonic agent and to strengthen immune system)403)(405), treat colds(407), measles(407), bronchial inflammations(407), etc. Recent studies showed that Shiitake mushrooms are also consisted properties of anti cancers(403)(404), anti microorganisms(407)(408) such as  HIV)410)(411)and hepatitis virus(407)(412), enhanced immune system(403)(405)(406) against inflammation(413)(414) causes of chronic inflammatory diseases(415) and the development of free radicals(414)(416), lowering cholesterol levels(407)(417)(418), treating heart disease(407)(419), diabetes(407)(420), etc....



Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months   

 
References
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(20) Polycystic ovary syndrome: metabolic consequences and long-term management by Carmina E1.(PubMed)
(21) Arterial stiffness is increased in asymptomatic nondiabetic postmenopausal women with a polycystic ovary syndrome phenotype by Armeni E1, Stamatelopoulos K, Rizos D, Georgiopoulos G, Kazani M, Kazani A, Kolyviras A, Stellos K, Panoulis K, Alexandrou A, Creatsa M, Papamichael C, Lambrinoudaki I.(PubMed)
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(268) New dog and new tricks: evolving roles for IL-33 in type 2 immunity by Lott JM1, Sumpter TL1, Turnquist HR2.(PubMed)
(285) FoodImmunity, and the Microbiome by Tilg H1, Moschen AR2.(PubMed)
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(335) Ginger in the prevention of nausea and vomiting: a review by Palatty PL1, Haniadka R, Valder B, Arora R, Baliga MS.(PubMed)
(336) Influence of a specific ginger combination on gastropathy conditions in patients with osteoarthritis of the knee or hip by Drozdov VN1, Kim VA, Tkachenko EV, Varvanina GG.(PubMed)
(337) Antiproliferative properties of Padma Lax and its components ginger and elecampane by Hofbauer S1, Kainz V, Golser L, Klappacher M, Kiesslich T, Heidegger W, Krammer B, Hermann A, Weiger TM.(PubMed)
(338) The postulated mechanism of the protective effect of ginger on the aspirin induced gastric ulcer: Histological and immunohistochemical studies by Salah Khalil M1.(PubMed)
(339) Zingiber officinale ameliorates allergic asthma via suppression of Th2-mediated immune response by Khan AM1, Shahzad M, Raza Asim MB, Imran M, Shabbir A.(PubMed)
(340) Effects of various fragrant ingredients on desmopressin-induced fluid retention in mice by Morimoto Y1, Shibata Y.(PubMed)
(341) Pharmacological basis for the medicinal use of ginger in gastrointestinal disorders by Ghayur MN1, Gilani AH.(PubMed)
(342) Identification of serotonin 5-HT1A receptor partial agonists in ginger by Nievergelt A1, Huonker P, Schoop R, Altmann KH, Gertsch J.(PubMed)
(343) Antidepressant-like synergism of extracts from magnolia bark and ginger rhizome alone and in combination in mice by Yi LT1, Xu Q, Li YC, Yang L, Kong LD.(PubMed)
(344) Comparative effects of dietary ginger (Zingiber officinale) and garlic (Allium sativum) investigated in a type 2 diabetes model of rats by Islam MS1, Choi H.(PubMed)
(345) The effect of ginger (Zingiber officinale) on glycemic markers in patients with type 2 diabetes by Shidfar F, Rajab A, Rahideh T, Khandouzi N, Hosseini S, Shidfar S.(PubMed)
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(347) Anti-cancer activity of Ginger (Zingiber officinale) leaf through the expression of activating transcription factor 3 in human colorectal cancer cells by Park GH, Park JH, Song HM, Eo HJ, Kim MK, Lee JW, Lee MH, Cho KH, Lee JR, Cho HJ, Jeong JB1.(PubMed)
(348) Effects of ginger (Zingiber officinale Roscoe) on DNA damage and development of urothelial tumors in a mouse bladder carcinogenesis model by Bidinotto LT1, Spinardi-Barbisan AL, Rocha NS, Salvadori DM, Barbisan LF.(PubMed)
(349) Gelam honey and ginger potentiate the anti cancer effect of 5-FU against HCT 116 colorectal cancer cells by Hakim L1, Alias E, Makpol S, Ngah WZ, Morad NA, Yusof YA.(PubMed)
(350) Immunity: plants as effective mediators by Sultan MT1, Butt MS, Qayyum MM, Suleria HA.(PubMed)
(351) 6-Shogaol inhibits chondrocytes' innate immune responses and cathepsin-K activity by Villalvilla A1, da Silva JA, Largo R, Gualillo O, Vieira PC, Herrero-Beaumont G, Gómez R.(PubMed)
(352) Zingiber officinale: A Potential Plant against Rheumatoid Arthritis by Al-Nahain A1, Jahan R2, Rahmatullah M1.(PubMed)
(353) Theoretical and experimental study on lipophilicity and wound healing activity of ginger compounds by Bakht MA1, Alajmi MF2, Alam P2, Alam A3, Alam P3, Aljarba TM3.(PubMed)
(354) A Newly Designed Curcumin Analog Y20 Mitigates Cardiac Injury via Anti-Inflammatory and Anti-Oxidant Actions in Obese Rats by Qian Y1, Zhong P2, Liang D1, Xu Z1, Skibba M1, Zeng C3, Li X1, Wei T3, Wu L4, Liang G1.(PubMed)
(355) Protective effects of various dosage of Curcumin against morphine induced apoptosis and oxidative stress in rat isolated hippocampus by Motaghinejad M1, Karimian M2, Motaghinejad O3, Shabab B4, Yazdani I5, Fatima S2.(PubMed)
(356) Hypoglycemic activity of curcumin synthetic analogues in alloxan-induced diabetic rats by Das KK1, Razzaghi-Asl N, Tikare SN, Di Santo R, Costi R, Messore A, Pescatori L, Crucitti GC, Jargar JG, Dhundasi SA, Saso L.(PubMed)
(357) Curcumin enhances recovery of pancreatic islets from cellular stress induced inflammation and apoptosis in diabetic rats by Rashid K1, Sil PC2.(PubMed)
(358) Food preservatives sodium benzoate and propionic acid and colorant curcumin suppress Th1-type immune response in vitro by Maier E1, Kurz K, Jenny M, Schennach H, Ueberall F, Fuchs D.(PubMed)
(359) Gastroprotective effect of ethanolic extract of Curcuma xanthorrhiza leaf against ethanol-induced gastric mucosal lesions in Sprague-Dawley rats by Rahim NA1, Hassandarvish P2, Golbabapour S3, Ismail S4, Tayyab S4, Abdulla MA2.(PubMed)
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(361) Novel curcumin-loaded gel-core hyaluosomes with promising burn-wound healing potential: Development, in-vitro appraisal and in-vivo studies by El-Refaie WM1, Elnaggar YS2, El-Massik MA1, Abdallah OY3(PubMed)
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(364) Effects of the extracts and an active compound curcumenone isolated from Curcuma zedoaria rhizomes on alcohol-induced drunkenness in mice by Kimura Y1, Sumiyoshi M, Tamaki T.(PubMed)
(365) The evaluation of anti-ulcerogenic effect of rhizome starch of two source plants of Tugaksheeree (Curcuma angustifolia Roxb. and Maranta arundinacea Linn.) on pyloric ligated rats by Rajashekhara N1, Ashok BK2, Sharma PP3, Ravishankar B4.(PubMed)
(366) Clinical evaluation of an Indian polyherbal topical formulation in the management of eczema by Rawal RC1, Shah BJ, Jayaraaman AM, Jaiswal V.(PubMed)
(367) Antioxidant and anti-inflammatory effects of curcuminoid-piperine combination in subjects with metabolic syndrome: A randomized controlled trial and an updated meta-analysis by Panahi Y1, Hosseini MS2, Khalili N2, Naimi E2, Majeed M3, Sahebkar A4.(PubMed)
(368) Anti-Inflammatory Effects of Novel Standardized Solid Lipid Curcumin Formulations by Nahar PP1, Slitt AL, Seeram NP.(PubMed)
(369) Involvement of liver in diabetes mellitus: herbal remedies by Thent ZC1, Das S1.(PubMed)
(370) Beneficial effects of Chinese prescription Kangen-karyu on diabetes associated with hyperlipidemia, advanced glycation endproducts, and oxidative stress in streptozotocin-induced diabetic rats by Kim HY1, Okamoto T, Yokozawa T.(PubMed)
(371) Bactericidal activity of curcumin I is associated with damaging of bacterial membrane by Tyagi P1, Singh M1, Kumari H1, Kumari A1, Mukhopadhyay K1.(PubMed)
(372) Antimicrobial activity of turmeric extract and its potential use in food industry by Gul P1, Bakht J2.(PubMed)
(373) Efficacy of turmeric in the treatment of digestive disorders: a systematic review and meta-analysis protocol by Thavorn K1, Mamdani MM, Straus SE.(PubMed)
(374) Curcumol Induces Apoptosis in SPC-A-1 Human Lung Adenocarcinoma Cells and Displays Anti-neoplastic Effects in Tumor Bearing Mice by Tang QL1, Guo JQ, Wang QY, Lin HS, Yang ZP, Peng T, Pan XD, Liu B, Wang SJ, Zang LQ.(PubMed)
(375) Curcumol induces apoptosis via caspases-independent mitochondrial pathway in human lung adenocarcinoma ASTC-a-1 cells by Zhang W1, Wang Z, Chen T.(PubMed)
(376) Anti-cancer properties of terpenoids isolated from Rhizoma Curcumae--a review by Lu JJ1, Dang YY, Huang M, Xu WS, Chen XP, Wang YT.(PubMed)
(377) In vitro Antioxidant Potential in Sequential Extracts of Curcuma caesia Roxb. Rhizomes by Reenu J1, Azeez S1, Bhageerathy C1.(PubMed)
(378) Polyphenolic composition and antioxidant activities of 6 new turmeric (Curcuma longa L) accessions by Chinedum E1, Kate E, Sonia C, Ironkwe A, Andrew I.(PubMed)
(379) Curcuma as a functional food in the control of cancer and inflammation by Schaffer M1, Schaffer PM, Zidan J, Bar Sela G.(PubMed)
(380) Curcumin induces apoptosis in breast cancer cell lines and delays the growth of mammary tumors in neu transgenic mice by Masuelli L1, Benvenuto M, Fantini M, Marzocchella L, Sacchetti P, Di Stefano E, Tresoldi I, Izzi V, Bernardini R, Palumbo C, Mattei M, Lista F, Galvano F, Modesti A, Bei R.(PubMed)
(381) Induction of apoptosis and cell cycle arrest in cancer cells by in vivo metabolites of teas by Zhang G1, Miura Y, Yagasaki K.(PubMed)
(382) Antimutagenic and anticarcinogenic activity of tea polyphenols by Kuroda Y1, Hara Y.(PubMed)
(383) High oolong tea consumption predicts future risk of diabetes among Japanese male workers: a prospective cohort study by Hayashino Y1, Fukuhara S, Okamura T, Tanaka T, Ueshima H; HIPOP-OHP Research Group.(PubMed)
(384) Antihyperglycemic effect of oolong tea in type 2 diabetes by Hosoda K1, Wang MF, Liao ML, Chuang CK, Iha M, Clevidence B, Yamamoto S.(PubMed)
(385) Beneficial effects of oolong tea consumption on diet-induced overweight and obese subjects by He RR1, Chen L, Lin BH, Matsui Y, Yao XS, Kurihara H.(PubMed)
(386) Thermogenic ingredients and body weight regulation by Hursel R1, Westerterp-Plantenga MS.(PubMed)
(387) Hormesis, cellular stress response and vitagenes as critical determinants in aging and longevity by Calabrese V1, Cornelius C, Cuzzocrea S, Iavicoli I, Rizzarelli E, Calabrese EJ.(PubMed)
(388) The potential influence of plant polyphenols on the aging process by Cherniack EP1.(PubMed)
(389) Antiallergic constituents from oolong tea stem by Ohmori Y1, Ito M, Kishi M, Mizutani H, Katada T, Konishi H.(PubMed)
(390) [Effect of tea extracts, catechin and caffeine against type-I allergic reaction].[Article in Japanese] by Shiozaki T1, Sugiyama K, Nakazato K, Takeo T.(PubMed)
(391) Antibacterial activity of Iranian green and black tea on streptococcus mutans: an in vitro study by Naderi NJ1, Niakan M, Kharazi Fard MJ, Zardi S.(PubMed)
(392) Overview of antibacterial, antitoxin, antiviral, and antifungal activities of tea flavonoids and teas by Friedman M1.(PubMed)
(393) Mechanisms of hypolipidemic and anti-obesity effects of tea and tea polyphenols by Lin JK1, Lin-Shiau SY.(PubMed)
(394) Polyphenol-enriched oolong tea increases fecal lipid excretion by Hsu TF1, Kusumoto A, Abe K, Hosoda K, Kiso Y, Wang MF, Yamamoto S.(PubMed)
(395) Green and black tea consumption and risk of stroke: a meta-analysis by Arab L1, Liu W, Elashoff D.(PubMed)
(396) Does tea affect cardiovascular disease? A meta-analysis by Peters U1, Poole C, Arab L.(PubMed)
(397) Determination of tea components with antioxidant activity by Cabrera C1, Giménez R, López MC.(PubMed)
(398) Structural determination and DPPH radical-scavenging activity of two acylated flavonoid tetraglycosides in oolong tea (Camellia sinensis) by Lee VS1, Chen CR, Liao YW, Tzen JT, Chang CI.(PubMed)
(399) Evaluation of anti-inflammatory effects of green tea and black tea: A comparative in vitro study by Chatterjee P1, Chandra S, Dey P, Bhattacharya S.(PubMed)
(400) Anti-inflammatory and anti-oxidative effects of the green tea polyphenol epigallocatechin gallate in human corneal epithelial cells by Cavet ME1, Harrington KL, Vollmer TR, Ward KW, Zhang JZ.(PubMed)
(401)  Immunomodulatory effects of EGCG fraction of green tea extract in innate and adaptive immunity via T regulatory cells in murine model by Kuo CL1, Chen TS, Liou SY, Hsieh CC.(PubMed)
(402) Immunomodulating effects of epigallocatechin-3-gallate from green tea: mechanisms and applications by Pae M1, Wu D.(PubMed)
(403) Structure and inducing tumor cell apoptosis activity of polysaccharides isolated from Lentinus edodes by Wang KP1, Zhang QL, Liu Y, Wang J, Cheng Y, Zhang Y.(PubMed)
(404) Polysaccharides from Tricholoma matsutake and Lentinus edodes enhance 5-fluorouracil-mediated H22 cell growth inhibition by Ren M, Ye L, Hao X, Ren Z, Ren S, Xu K, Li J.(PubMed)
(405) Structure and immuno-stimulating activities of a new heteropolysaccharide from Lentinula edodes by Xu X1, Yan H, Zhang X.(PubMed)
(406) Dietary supplementation with rice bran fermented with Lentinus edodes increases interferon-γ activity without causing adverse effects: a randomized, double-blind, placebo-controlled, parallel-group study by Choi JY, Paik DJ, Kwon DY, Park Y1.(PubMed)
(407) Lentinus edodes: a macrofungus with pharmacological activities by Bisen PS1, Baghel RK, Sanodiya BS, Thakur GS, Prasad GB.(PubMed)
(408) An examination of antibacterial and antifungal properties of constituents of Shiitake (Lentinula edodes) and oyster (Pleurotus ostreatus) mushrooms by Hearst R1, Nelson D, McCollum G, Millar BC, Maeda Y, Goldsmith CE, Rooney PJ, Loughrey A, Rao JR, Moore JE.(PubMed)
(409) Antimicrobial properties of shiitake mushrooms (Lentinula edodes) by Rao JR, Smyth TJ, Millar BC, Moore JE.(PubMed)
(410) A placebo-controlled trial of the immune modulator, lentinan, in HIV-positive patients: a phase I/II trial by Gordon M1, Bihari B, Goosby E, Gorter R, Greco M, Guralnik M, Mimura T, Rudinicki V, Wong R, Kaneko Y.(PubMed)
(411) A phase II controlled study of a combination of the immune modulator, lentinan, with didanosine (ddI) in HIV patients with CD4 cells of 200-500/mm3 by Gordon M1, Guralnik M, Kaneko Y, Mimura T, Goodgame J, DeMarzo C, Pierce D, Baker M, Lang W.(PubMed)
(412) [Liver protective effect of Lentinula edodes mycelia(LEM)].[Article in Japanese] by Yagi K1.(PubMed)
 (413) Anti-inflammatory effects of five commercially available mushroom species determined in lipopolysaccharide and interferon-γ activated murine macrophages by Gunawardena D1, Bennett L, Shanmugam K, King K, Williams R, Zabaras D, Head R, Ooi L, Gyengesi E, Münch G.(PubMed)
(414) Effect of shiitake (Lentinus edodes) extract on antioxidant and inflammatory response to prolonged eccentric exercise by Zembron-Lacny A1, Gajewski M, Naczk M, Siatkowski I.(PubMed)
(415) Both common and specialty mushrooms inhibit adhesion molecule expression and in vitro binding of monocytes to human aortic endothelial cells in a pro-inflammatory environment by Martin KR1.(PubMed)
(416) Fumigation with essential oils improves sensory quality and enhanced antioxidant ability of shiitake mushroom (Lentinus edodes) by Jiang T1, Luo Z2, Ying T3.(PubMed)
(417) Antihyperlipidemic Effect of Dietary Lentinus edodes on Plasma, Feces and Hepatic Tissues in Hypercholesterolemic Rats by Yoon KN1, Alam N, Lee JS, Cho HJ, Kim HY, Shim MJ, Lee MW, Lee TS.(PubMed)
(418) Cholesterol-lowering effects of maitake (Grifola frondosa) fiber, shiitake (Lentinus edodes) fiber, and enokitake (Flammulina velutipes) fiber in rats by Fukushima M1, Ohashi T, Fujiwara Y, Sonoyama K, Nakano M.(PubMed)
(419) Effects of Lentinus edodes mycelia on dietary-induced atherosclerotic involvement in rabbit aorta by Yamada T1, Oinuma T, Niihashi M, Mitsumata M, Fujioka T, Hasegawa K, Nagaoka H, Itakura H.(PubMed)
(420) Protective effects of fractional extracts from Panellus serotinus on non-alcoholic fatty liver disease in obese, diabetic db/db mice by Inafuku M1, Nagao K, Nomura S, Shirouchi B, Inoue N, Nagamori N, Nakayama H, Toda T, Yanagita T.(PubMed)