Rheumatoid Arthritis
Rheumatoid Arthritis is defined a chronic disorder as a result of
inflammation, affecting mostly the flexible (synovial) joints and
tissues and organs in the body. The disease affects more women than in
men and generally occurs after the ages of 40 and diminishes the quality
of life of many elders.
omplications
1. Osteoporosis.
People who develop Rheumatoid arthritis can induce the a condition that
weakens your bones and makes them more prone to fracture as a result of
certain medication intake. Dr Lee SG, and the research team at the Pusan
National University School of Medicine, showed that the prevalence of
osteoporosis in the RA patients was 1.9 times higher than in healthy
subjects. Glucocorticoid use was a risk factor for generalized bone loss
in female RA patients(23).
2. Carpal tunnel syndrome
Carpal tunnel syndrome is defined as a condition of pressure on the
nerve in the wrist that supplies feeling and movement to parts of the
hand. If affects your wrists, it can compress the nerves of your hand
and fingers. There is a report of a case of carpal
tunnel syndrome caused by volar dislocation of the lunate in a patient
with rheumatoid arthritis. A 74-year-old woman complained of numbness in
her fingers. Carpal tunnel syndrome was diagnosed, and carpal tunnel
release was performed. However, the symptoms recurred(24).
3. Heart involvement
Scientists at the University of Palermo indicated that RA resulted
significantly associated to pericardial effusion (OR 10.7; 95% CI
5.0-23.0), valvular nodules (OR 12.5; 95% CI 2.8-55.4), tricuspidal
valve insufficiency (OR 5.3; 95% CI 2.4-11.6), aortic valve stenosis (OR
5.2; 95% CI 1.1-24.1), mitral valve insufficiency (OR 3.4; 95% CI
1.7-6.7), aortic valve insufficiency (OR 1.7; 95% CI 1.0-2.7), combined
valvular alterations (OR 4.3; 95% CI 2.3-8.0), mitral valve thickening
and/or calcification (OR 5.0; 95% CI 2.0-12.7), aortic valve thickening
and/or calcification (OR 4.4; 95% CI 1.1-17.4), valvular thickening
and/or calcification (OR 4.8; 95% CI 2.2-10.5), and mitral valve
prolapse (OR 2.2; 95% CI 1.2-4.0)(25).
4. Interstitial lung disease (ILD)
People with rheumatoid arthritis have an increased risk of interstitial lung disease (ILD). In
the study to describe the evolution of lung function in a cohort of
rheumatoid arthritis (RA) patients with interstitial lung disease
(ILD)found that Patients with RA and ILD may have an improvement in the
FVC after a treatment with high doses of corticosteroids and disease
modifying antirheumatic drugs (DMARDs)(26).
5. Dry eye syndrome and Sjogren’s syndrome
In the evaluate the prevalence of dry eye and secondary Sjogren’s
syndrome using salivary scintigraphy found that awareness and detection
of dry eye syndrome and secondary Sjogren’s syndrome in rheumatoid
arthritis was crucial for evaluation of their severity and proper
management(27).
6. Cerebral vasculitis
There is a report of a 64-year-old woman was suffering from rheumatoid
arthritis since the age of 57. At the age of 62, she manifested
episcleritis of the eyes and rheumatoid nodules in the skin, and
rheumatoid factor in the blood became high. These findings indicated the
presence of systemic vasculitis, and she was treated with
prednisolone(28).
7. Etc.
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Sources
(23) http://www.ncbi.nlm.nih.gov/pubmed/22709491
(24) http://www.ncbi.nlm.nih.gov/pubmed/17165005
(25) http://www.ncbi.nlm.nih.gov/pubmed/22703938
(26) http://www.ncbi.nlm.nih.gov/pubmed/22341526
(27) http://www.ncbi.nlm.nih.gov/pubmed/22696854
(28) http://www.ncbi.nlm.nih.gov/pubmed/9805988
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