Reversible cerebral vasoconstriction syndrome (RCVS)
Reversible cerebral vasoconstriction syndrome, sometimes called
Call-Fleming syndrome is defined as a condition of disease of the
arteries of which the brain develops a blood vessels spasm that leads to
multifocal arterial constriction and dilation, causing the sudden onset
of a severe headache (2)
Causes and risk factors
Some researchers suggested reversible cerebral vasoconstriction syndrome (RCVS) may be a results
from a transient disturbance of the circle of arteries that supply
blood to the brain of which leads to its constriction.
1. Antidepressants
Antidepressants used to treat depression, anxiety disorders, and some personality disorders may increase risk of diffuse cerebral vasoconstriction(5)
2. Nasal decongestants
In the investigation conducted by Lariboisière Hospital of clinical, neuroimaging and outcome data of 67 consecutive patients
prospectively diagnosed over 3 years in our institution with an
angiographically confirmed RCVS, 43 females and 24 males with a mean age of 42 years (19-70). RCVS was
spontaneous in 37% of patients and secondary in the 63% others, to
postpartum in 5 and to exposure to various vasoactive substances in 37,
mainly cannabis, selective serotonin-recapture inhibitors and nasal decongestants(6)
3. Eletriptan
A pediatric case of reversible cerebral vasoconstriction syndrome with
cortical subarachnoid hemorrhage, suggested that Eletriptan might cause
vasoconstriction of cerebral arteries. Although
most patients with RCVS are adults and pediatric cases are rare, RCVS
should be considered in a child complaining of severe headache(7)
4. Vasoconstrictive drug
exposure and migraine
In the study of clinical, laboratory, and imaging features of patients with reversible cerebral vasoconstriction syndromes evaluated at 2 academic centers, compare subgroups, conducted by
6. Evoked by pregnancy(4)
7. Exposure to vasoactive substances such as angiotensin II, epinephrine, norepinephrine, vasopressin can lead to constrictor dilate of blood vessels)(4)
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Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/20816453
(2) http://www.ncbi.nlm.nih.gov/pubmed/19220301
(3) http://www.ncbi.nlm.nih.gov/pubmed/20936928
(4) http://www.ncbi.nlm.nih.gov/pubmed/21179608
(5) http://www.ncbi.nlm.nih.gov/pubmed/16832100
(6) http://www.ncbi.nlm.nih.gov/pubmed/18025032
(7) http://www.sciencedirect.com/science/article/pii/S038776041200006X
(8) http://www.medscape.org/viewarticle/748234_3
(9) http://www.ncbi.nlm.nih.gov/pubmed/22000400
Health Researcher and Article Writer. Expert in Health Benefits of Foods, Herbs, and Phytochemicals. Master in Mathematics & Nutrition and BA in World Literature and Literary criticism. All articles written by Kyle J. Norton are for information & education only.
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