Monday, 18 November 2013

Phytochemicals and Anxiety

Anxiety is a psychological and physiological state triggered by feelings of fear, worry, uneasiness and dread, etc. It is a normal reaction to a stress that allows a person to cope with the situation during emotionally difficult time. But when when anxiety symptoms escalate or become excessive, it can lead to anxiety disorder.
Types of anxiety disorder
1. Panic disorder
Panic disorder is a type of anxiety disorder defined as a condition of sudden feelings of terror for no reason. It can happens any without cause. The condition affects more often in women mau ve as a result of stress or fear wiothout reason

2. Obsessive-compulsive disorder
Obsessive-compulsive disorder is a type of anxiety disorder defined as condition of repeated absessions. A woman with obsessive-compulsive disorder tries to repeat the same complusive action over and over again to prevent something to happen with no reason. Example, some women with the disorder may try to clean away germs by clearing the same over and over again compulsively.

3. Post-traumatic stress disorder
Post-traumatic disorder is type of anxiety disorder defined as a condition of living through a horrible experience that can make you fear after the event was over. Some women may fear the sound of win after going the bad hurricane.

4. Phobias
Phobias is a type of anxiety disorder defined as a condition in which a person has strong fear of something which post no danger to him/her. Example, some people affaid of height,..

5. Generalized anxiety disorder
Generalized anxiety disorder is another type of anxiety disorder defined as a condition in which a person feels anxious from time to time when he/she is stressful. If the disease has affected the quality of life and daily activities, you may has general anxiety disorder.

6. Etc.

Types of Food to prevent and treat anxiety 
1. Green tea
In the study of to examine the acute effects of L-theanine in comparison with a standard benzodiazepine anxiolytic, alprazolam and placebo on behavioural measures of anxiety in healthy human subjects using the model of anticipatory anxiety (AA), indicated that some evidence for relaxing effects of L-theanine during the baseline condition on the tranquil-troubled subscale of the VAMS. Alprazolam did not exert any anxiolytic effects in comparison with the placebo on any of the measures during the relaxed state. Neither L-theanine nor alprazalam had any significant anxiolytic effects during the experimentally induced anxiety state(1). Others study suggested that L-theanine does not produce anxiolysis by modulation of the GABAA receptor; however, in combination with midazolam, a synergistic or additive effect was demonstrated by decreased anxiety and both fine and basic motor movements. These data may provide direction for further studies examining L-theanine and its effects on anxiety and motor activity(2).

2. Skins and seeds of grapes
In the study  to determine the effect of resveratrol on hippocampal damage and behavioral deficits in 7-day-old rat pups subjected to contusion injury, showed that  treatment with resveratrol decreased anxiety and increased cortex/hippocampus dependent memory of animals subjected to blunt head trauma. These results show that acute treatment of resveratrol has a neuroprotective role against trauma induced hippocampal neuron loss and associated cognitive impairment in rats(2).

3. Turcumin
In the study to evaluate the effect of curcumin (10 and 20mg/kg), an active constituent of Curcuma longa was evaluated for its antianxiety-like activity in mice subjected to immobilization-induced restraint stress for 6h, indicated that the combination of aminoguanidine and curcumin significantly decreased the plasma nitrite levels as compared to curcumin and aminoguanidine per se in stressed mice. Curcumin and aminoguanidine did not produce any significant change in brain GABA contents of the animals. Diazepam (2mg/kg) produced significant anxiolytic-like effect only in unstressed mice, but could not exert significant anxiolysis in stressed mice. However, diazepam significantly increased GABA contents in both unstressed and stressed mice as compared to respective control groups. These findings suggest the possible involvement of only inducible NOS and not neuronal NOS in antianxiety-like effect of curcumin(3).

4.  Deep sea fish and Algae
Omega 3 fatty acids found abundantly in deep sea fish and kelp has exerted the protective effect against depression symptoms of anxiety. In the study to  determine whether omega-3 PUFAs reduce the rate of progression to first-episode psychotic disorder in adolescents and young adults aged 13 to 25 years with subthreshold psychosis. showed that long-chain omega-3 PUFAs reduce the risk of progression to psychotic disorder and may offer a safe and efficacious strategy for indicated prevention in young people with subthreshold psychotic states(4).

5. Etc.

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