Infertility is defined as inability of a couple to conceive after 12
months of unprotected sexual intercourse or can not carry the pregnancy
to term. It effects over 5 millions couple alone in the U. S. and many
times more in the world. Because of unawareness of treatments, only 10%
seeks help from professional specialist. the unexplained causes of
infertility is defined as if the woman and men reproductive system are
function normally but the present-day medical technology and medical doctors can not give a reason why the couple can not conceive. What is male infertility hypoosmotic swelling test (HOST)?
I. Definition
Hypoosmotic
swelling test (HOST) is the test used to identify sperm membrane for
structure integrity by examining how the sperm tail reacts to special
sugar and salt. Only healthy sperm can react in this circumstance.
II. Procedure
The
HOS test was performed by mixing special sugar and salt in distilled
water. The mixture was incubated and immediately examined under a
microscope. The percentage of reacted sperm (curled tails) and
non-reacted sperm (non-curled tails) were assessed.
III. Diagnosis
1.
A sample sperm is considered normal if more than 60% response to the
swollen spermatozoa. otherwise the tested sample is considered to have
poor sperm membrane structure integrity. It is said the hypoosmotic
swelling test result is predictive of the sperm penetration test. If the
tested sample fail, it may need some other technical support to by-pass
the sperm penetration process.
IV. Risk
Although the
hypoosmotic swelling test is less time consuming and can help to
determine the the sperm fertilization capacity, the result is not 100%
guaranteed. For the couple to conceive, it take more than the
hypoosmotic swelling test for a successful pregnancy, please make sure
that other health problems have been taking care of.
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