Infertility is defined as inability of a couple to conceive after 12
months of unprotected sexual intercourse or can not carry the pregnancy
to term. It effects over 5 millions couple alone in the U. S. and many
times more in the world. Because of unawareness of treatments, only 10%
seeks help from professional specialist. the unexplained causes of
infertility is defined as if the woman and men reproductive system are
function normally but the present-day medical technology and medical doctors can not give a reason why the couple can not conceive .In this article, we will discuss what is male infertility hemizona assay?
I. Definition
Hemizona
assay is an analysis to compare the binding capacity of sample sperm of
the unfertilized male to the sperm of the fertilized male through
manual hand cutting versus micro manipulation in IVF and IUI
fertilization.
II. Diagnosis
After splitting the mature
and normal egg in half. 1/2 is tested by sample sperm of the infertile
male and the other half is tested by the fertilized male sperm through
manual hand cutting or micro manipulation. Then the number of sperm
bounds to each half and is calculated, and the infertile male's sperm is
divided by that from the fertile male's sperm. A figure of less than
0.60 indicates abnormal infertile male's sperm.
Although the
success rate of this test is not 100%, the HZA has been found to be
predictive of IVF and IUI outcome with positive and negative values of
83% and 95% respectively, according to one study. Therefore, if an
infertile couple decides to go through IUI or IVF for conception then
the hemizoma test is necessary.
III. Risk
There is no
guarantee that a couple who scores high in the hemizoma test will be
successful to conceive via IVF or IUI, because there are other factors
that may interfere with the process after the fertilized egg or embryo
was implanted into the uterus.
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