Infertility is defined as inability of a couple to conceive after 12
months of unprotected sexual intercourse. It effects over 5 millions
couple alone in the U. S. and many times more in the world. Because of
unawareness of treatments, only 10% seeks help from professional
specialist. In this article, we will discuss the immunity causes of
infertility.
I. Definition
Malfunction of immune system
interferes with the reproductive processes including the inflammation to
cells. These natural processes are vital for preparation of ovulation,
implantation of a embryo ( malfunction of immune system may cause
abnormal endometrial lining) and production of sperm quality and
quantity (Malfunction of immune system may cause antibody attack his own
sperm), etc.
II. How immune system causes infertility
1. Sperm agglutination
Sperm
agglutination is a condition in which sperms clumping together due to
infection or antibody reaction because of immune system attacking the
sperm thereby, reducing the sperm ability to fertilize the egg and
increasing the risk of infection.
2. Testicular injure
Testicle
injure caused by what ever reason may increase the risk of immune
system attacking the man's sperm due to inflammation and infection.
3. Testicular cancer
Testicular
cancer is defined as abnormal cells growth caused by inability of
immune system failure to regulate cells duplication, become cancerous in
the testicle leading to poor sperm count and decreasing the risk of
fertility. Researchers believe men with poor quality of sperm production
is considered as high risk to develop testicle cancer than others who
do not.
4. Antisperm antibody
Antibody is an chemical made by
our body to help the immune system to identify foreign invasion such as
bacteria and virus. In case of anti sperm antibody, the immune system
attacks fetus and the sperm which interferes the sperm quality, movement
and sperm cervical invasion resulting in increasing the risk of
infertility for women and men alike.
5. Pyospermia
Pyospermia
is condition in which high levels of white blood cell count exists in
the sperm. It is caused by infection of sexual transmitted disease
somewhere in the body. Sometimes such infection may cause the immune
system recognizes the sperm as an invader and kill it.
6 Aniphospholipid antibody
It is defined as a condition in which a class of protein attacks an early development of pregnancy.
8. Antinuclear antibody
Antinuclear
antibody is antibody directed against contents of the cell nucleus
leading to miscarriage caused by immunity disorder.
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